UM

Browse/Search Results:  1-10 of 13 Help

Selected(0)Clear Items/Page:    Sort:
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
Favorite  |  View/Download:21/0  |  Submit date:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
MLKL mediates apoptosis via a mutual regulation with PERK/eIF2 alpha pathway in response to reactive oxygen species generation Journal article
APOPTOSIS, 2018,Volume: 23,Issue: 9-10,Page: 521-531
Authors:  Wen‑Xiang Cao;  Ting Li;  Zheng‑Hai Tang;  Le‑Le Zhang;  Zhao‑Yu Wang;  Xia Guo;  Min‑Xia Su;  Xiuping Chen;  Jin‑Jian Lu
Favorite  |  View/Download:8/0  |  Submit date:2020/01/09
Mlkl  Eif2α  Ros  Apoptosis  Chelerythrine  
Downregulation of Cyclin B1 mediates nagilactone E-induced G2 phase cell cycle arrest in non-small cell lung cancer cells Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 830,Page: 17-25
Authors:  Zhang, Le-Le;  Feng, Zhe-Ling;  Su, Min-Xia;  Jiang, Xiao-Ming;  Chen, Xiuping;  Wang, Yitao;  Li, Ao;  Lin, Li-Gen;  Lu, Jin-Jian
View  |  Adobe PDF(3226Kb)  |  Favorite  |  View/Download:559/32  |  Submit date:2018/10/30
Nagilactone e  Non-small Cell Lung Cancer  Cyclin B1  Cell Cycle  Apoptosis  
Anticancer drug discovery from Chinese medicinal herbs Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Huang, Mu-Yang;  Zhang, Le-Le;  Ding, Jian;  Lu, Jin-Jian
Favorite  |  View/Download:98/0  |  Submit date:2018/10/30
Chinese Medicinal Herbs  Anticancer  Drug Discovery  Natural Products  Formulae  
Investigational Hypoxia-Activated Prodrugs: Making Sense of Future Development Journal article
Current Drug Targets, 2018,Volume: 20
Authors:  Min-Xia Su;  Le-Le Zhang;  Zhang-Jian Huang;  Jia-Jie Shi;  Jin-Jian Lu
Favorite  |  View/Download:7/0  |  Submit date:2019/01/14
Hypoxia-activated Prodrug  Topoisomerase Ii Inhibitors  Dna Alkylating Agents  Targeted Drugs  Reductases Activity  Patient Selection  Clinical Progress  
Osimertinib (AZD9291) decreases programmed death ligand-1 in EGFR-mutated non-small cell lung cancer cells Journal article
ACTA PHARMACOLOGICA SINICA, 2017,Volume: 38,Issue: 11,Page: 1512-1520
Authors:  Jiang, Xiao-Ming;  Xu, Yu-Lian;  Huang, Mu-Yang;  Zhang, Le-Le;  Su, Min-Xia;  Chen, Xiuping;  Lu, Jin-Jian
Favorite  |  View/Download:26/0  |  Submit date:2018/10/30
Non-small Cell Lung Cancer  Egfr  Osimertinib  Pd-l1  Ubiquitin-proteasome System  Mg-132  Bortezomib  Gsk3 Beta  Licl  
The effects and mechanisms of two main constituents from Glycyrrhiza uralensis Fisch-induced autophagy in non-small cell lung cancer Conference paper
BIOCHEMICAL PHARMACOLOGY, Aberdeen, SCOTLAND, SEP 27-29, 2017
Authors:  Tang, Zheng-Hai;  Zhang, Le-Le;  Chen, Xin;  Chen, Xiuping;  Wang, Yitao;  Lu, Jin-Jian
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Therapeutic potential of Rhizoma Alismatis: a review on ethnomedicinal application, phytochemistry, pharmacology, and toxicology Journal article
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 2017,Volume: 1401,Issue: 1,Page: 90-101
Authors:  Zhang, Le-Le;  Xu, Wen;  Xu, Yu-Lian;  Chen, Xiuping;  Huang, Mingqing;  Lu, Jin-Jian
Favorite  |  View/Download:15/0  |  Submit date:2018/10/30
Rhizoma Alismatis  Ethnomedicinal Application  Phytochemistry  Pharmacology  Toxicology  
Norditerpenoids and Dinorditerpenoids from the Seeds of Podocarpus nagi as Cytotoxic Agents and Autophagy Inducers Journal article
JOURNAL OF NATURAL PRODUCTS, 2017,Volume: 80,Issue: 7,Page: 2110-2117
Authors:  Feng, Zhe-Ling;  Zhang, Le-Le;  Zheng, Yuan-Dong;  Liu, Qian-Yu;  Liu, Jing-Xin;  Feng, Lu;  Huang, Li;  Zhang, Qing-Wen;  Lu, Jin-Jian;  Lin, Li-Gen
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
Solasodine Induces Apoptosis, Affects Autophagy, and Attenuates Metastasis in Ovarian Cancer Cells Journal article
PLANTA MEDICA, 2017,Volume: 83,Issue: 3-4,Page: 254-260
Authors:  Xu, Xiao-Huang;  Zhang, Le-Le;  Wu, Guo-Sheng;  Chen, Xin;  Li, Ting;  Chen, Xiuping;  Wang, Yi-Tao;  Lu, Jin-Jian
Favorite  |  View/Download:22/0  |  Submit date:2018/10/30
Ovarian Cancer  Solasodine  Apoptosis  Autophagy  Migration  Invasion