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Discovery, synthesis, and functional characterization of a novel neuroprotective natural product from the fruit of alpinia oxyphylla for use in Parkinson's disease through LC/MS-based multivariate data analysis-guided fractionation Journal article
Journal of Proteome Research, 2016,Volume: 15,Issue: 8,Page: 2595-2606
Authors:  Guohui Li;  Zaijun Zhang;  Quan Quan;  Renwang Jiang;  Samuel S.W. Szeto;  Shuai Yuan;  Wing-tak Wong;  Herman H. C. Lam;  Simon Ming-Yuen Lee;  Ivan K. Chu
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Natural Products  Neuroprotective  Nrf2  Parkinson's Disease  Proteomics  
Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca2+-Activated K+ Channels (BKCa) Journal article
Evidence-based Complementary and Alternative Medicine, 2016,Volume: 2016
Authors:  Tseng H.H.L.;  Vong C.T.;  Leung G.P.-H.;  Seto S.W.;  Kwan Y.W.;  Lee S.M.-Y.;  Hoi M.P.M.
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Relaxation effect of a novel Danshensu/tetramethylpyrazine derivative on rat mesenteric arteries Journal article
European Journal of Pharmacology, 2015,Volume: 761,Page: 153-160
Authors:  Li R.W.-S.;  Yang C.;  Shan L.;  Zhang Z.;  Wang Y.;  Kwan Y.W.;  Lee S.M.Y.;  Hoi M.P.M.;  Chan S.W.;  Cheung A.C.;  Cheung K.H.;  Leung G.P.H.
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Calcium Channel  Danshensu Tetramethylpyrazine  Mesenteric Artery  Relaxation  
Basal Flt1 tyrosine kinase activity is a positive regulator of endothelial survival and vascularization during zebrafish embryogenesis Journal article
Biochimica et Biophysica Acta - General Subjects, 2015,Volume: 1850,Issue: 2,Page: 373-384
Authors:  Li S.;  Zhou X.L.;  Dang Y.Y.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.H.;  Lee S.M.-Y.;  Hoi M.P.M.
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Calycosin  Endothelial Cell  Flt1  Molecular Docking  Vegf Receptor Inhibitor  Zebrafish  
Examining the neuroprotective effects of protocatechuic acid and chrysin on in vitro and in vivo models of Parkinson disease Journal article
Free Radical Biology and Medicine, 2015,Volume: 84,Page: 331
Authors:  Zaijun Zhang;  Guohui Li;  Samuel S.W. Szeto;  Cheong Meng Chong;  Quan Quan;  Chen Huang;  Wei Cui;  Baojian Guo;  Yuqiang Wang;  Yifan Han;  K.W. Michael Siu;  Simon Ming Yuen Lee;  Ivan K. Chu
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Anti-inflammation  Freeradicals  Neuroprotection  Nrf2 Nf-κb  Parkinsondisease  Proteomics  
VEGFR tyrosine kinase inhibitor II (VRI) induced vascular insufficiency in zebrafish as a model for studying vascular toxicity and vascular preservation Journal article
Toxicology and Applied Pharmacology, 2014,Volume: 280,Issue: 3,Page: 408-420
Authors:  Li S.;  Dang Y.Y.;  Oi Lam Che G.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.H.;  Lee S.M.Y.;  Hoi M.P.M.
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Cardiovascular Protective Agents  Cardiovascular Toxicity  Vascular Insufficiency  Zebrafish Model  
Quick, sensitive and specific detection and evaluation of quantification of minor variants by high-throughput sequencing Journal article
Molecular BioSystems, 2014,Volume: 10,Issue: 2,Page: 206-214
Authors:  Leung R.K.-K.;  Dong Z.Q.;  Sa F.;  Chong C.M.;  Lei S.W.;  Tsui S.K.-W.;  Lee S.M.-Y.
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Transcriptome analysis in venom gland of the predatory giant ant dinoponera quadriceps: Insights into the polypeptide toxin arsenal of hymenopterans Journal article
PLoS ONE, 2014,Volume: 9,Issue: 1
Authors:  Torres A.F.C.;  Huang C.;  Chong C.-M.;  Leung S.W.;  Prieto-da-Silva A.R.B.;  Havt A.;  Quinet Y.P.;  Martins A.M.C.;  Lee S.M.Y.;  Radis-Baptista G.
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Uptake and protective effects of ergothioneine in human endothelial cells Journal article
Journal of Pharmacology and Experimental Therapeutics, 2014,Volume: 350,Issue: 3,Page: 691-700
Authors:  Li R.W.S.;  Yang C.;  Sit A.S.M.;  Kwan Y.W.;  Lee S.M.Y.;  Hoi M.P.M.;  Chan S.W.;  Hausman M.;  Vanhoutte P.M.;  Leung G.P.H.
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Involvement of organic cation transporter-3 and plasma membrane monoamine transporter in serotonin uptake in human brain vascular smooth muscle cells Journal article
Frontiers in Pharmacology, 2013,Volume: 4 FEB
Authors:  Li R.W.S.;  Yang C.;  Kwan Y.W.;  Chan S.W.;  Lee S.M.Y.;  Leung G.P.H.
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Monoamine Transporter  Organic Cation Transporter  Serotonin  Vascular Smooth Muscle Cells