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Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization Journal article
ACS CHEMICAL NEUROSCIENCE, 2019,Volume: 10,Issue: 5,Page: 2434-2449
Authors:  Chuwen Li;  Yaqi Bian;  Yu Feng;  Fan Tang;  Liang Wang;  Maggie Pui Man Hoi;  Dan Ma;  Chao Zhao;  Simon Ming Yuen Lee
Favorite | View/Download:225/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2020/01/16
Bhdpc  Ischemic Stroke  Microglia  Nf-κb  Creb  Pka  
BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappa B and Activating PKA/CREB Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Feng, Yu;  Hoi, Maggie P. M.;  Ma, Dan;  Zhao, Chao;  Zheng, Ying;  Lee, Simon M. Y.
Favorite | View/Download:34/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2018/10/30
Bhdpc  Neuroinflammation  Microglia  Nf-kappa b  Creb  Pka  
Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKK beta-Dependent AMPK Activation Journal article
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018,Volume: 11
Authors:  Li, Chuwen;  Zhang, Chao;  Zhou, Hefeng;  Feng, Yu;  Tang, Fan;  Hoi, Maggie P. M.;  He, Chengwei;  Ma, Dan;  Zhao, Chao;  Lee, Simon M. Y.
Favorite | View/Download:29/0 | TC[WOS]:23 TC[Scopus]:0 | Submit date:2018/10/30
Amp-activated Protein Kinase  Betulinic Acid  Calmodulin-dependent Protein Kinase Beta  Microglia Polarization  Neuroinflammation  
Alisol A 24-Acetate and Alisol B 23-Acetate Induced Autophagy Mediates Apoptosis and Nephrotoxicity in Human Renal Proximal Tubular Cells Journal article
FRONTIERS IN PHARMACOLOGY, 2017,Volume: 8
Authors:  Wang, Chunfei;  Feng, Liang;  Ma, Liang;  Chen, Haifeng;  Tan, Xiaobin;  Hou, Xuefeng;  Song, Jie;  Cui, Li;  Liu, Dan;  Chen, Juan;  Yang, Nan;  Wang, Jing;  Liu, Ying;  Zhao, Bingjie;  Wang, Gang;  Zhou, Yuanli;  Jia, Xiaobin
Favorite | View/Download:24/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/10/30
alisol A 24-acetate  alisol B 23-acetate  autophagy  apoptosis  nephrotoxicity  
Discovery of a novel neuroprotectant, BHDPC, that protects against MPP+/MPTP-induced neuronal death in multiple experimental models Journal article
Free Radical Biology and Medicine, 2015,Volume: 89,Page: 1057-1066
Authors:  Cheong-Meng Chong;  Dan Ma;  Chao Zhao;  Robin J.M. Franklin;  Zhong-Yan Zhou;  Nana Ai;  Chuwen Li;  Huidong Yu;  Tingjun Hou;  Tingjun Hou;  Simon Ming-Yuen Lee
Favorite | View/Download:17/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2018/11/06
Mpp++++  Neurodegeneration  Rat Organotypiccerebellarcultures  Zebrafish