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Experimental characterization and molecular dynamic simulation of ketoprofen-cyclodextrin complexes Journal article
CHEMICAL PHYSICS LETTERS, 2019,Volume: 736
Authors:  Qianqian Zhao;  Haoshi Gao;  Yan Su;  Tianhe Huang;  Jiahong Lu;  Hua Yu;  Defang Ouyang
Favorite  |  View/Download:318/0  |  Submit date:2019/12/04
Ketoprofen  Cyclodextrin Complexation  Molecular Dynamic Simulation  Molecular Mechanism  Binary System  
A novel dual sensitive polymer-gambogic acid conjugate: synthesis, characterization, and in vitro evaluation Journal article
NANOTECHNOLOGY, 2019,Volume: 30,Issue: 50
Authors:  Ke Song;  Zhaobo Wang;  Xue Liu;  Guolin Zhang;  Xin Wang;  DeFang Ouyang;  Mingrui Guo;  Lijiang Chen
Favorite  |  View/Download:10/0  |  Submit date:2020/03/25
Polymer-drug Conjugate  Gambogic Acid  Sensitive Drug Delivery  Cathepsin b  Glutathione  
Molecular Interactions for the Curcumin-Polymer Complex with Enhanced Anti-Inflammatory Effects Journal article
PHARMACEUTICS, 2019,Volume: 11,Issue: 9
Authors:  Yan He;  Hongfei Liu;  Wangqing Bian;  Yue Liu;  Xinyang Liu;  Shijing Ma;  Xi Zheng;  Zhiyun Du;  Kun Zhang;  Defang Ouyang
Favorite  |  View/Download:9/0  |  Submit date:2020/03/25
Curcumin  Polyvinylpyrrolidone (Pvp)  Solid Dispersions  Molecular Modeling  Drug-polymer Interactions  
Insight into the Dissolution Molecular Mechanism of Ternary Solid Dispersions by Combined Experiments and Molecular Simulations Journal article
AAPS PHARMSCITECH, 2019,Volume: 20,Issue: 7
Authors:  Run Han;  Tianhe Huang;  Xinyang Liu;  Xinyang Liu;  Haifeng Li;  Jiahong Lu;  Yuanhui Ji;  Huimin Sun;  Defang Ouyang
Favorite  |  View/Download:7/0  |  Submit date:2020/03/25
Solid Dispersion  Dissolution Effect  Molecular Modeling  Ternary System  
Investigating molecular interactions of high-loaded glipizide-HPMCAS microparticles by integrated experimental and modeling techniques Journal article
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019,Volume: 131,Page: 127-135
Authors:  Qiang Li;  Qianqian Zhao;  Qiufang Jing;  Xiaosi Ma;  Ning Chen;  Guobin Ren;  Defang Ouyang;  Fuzheng Ren
Favorite  |  View/Download:9/0  |  Submit date:2020/03/25
Glipizide  Hydroxypropyl Methylcellulose Acetate  Succinate (Hpmcas)  Molecular Interaction  Molecular Dynamics Simulation  
Three-Level Hepatotoxicity Prediction System Based on Adverse Hepatic Effects Journal article
MOLECULAR PHARMACEUTICS, 2019,Volume: 16,Issue: 1,Page: 393-408
Authors:  Lu Liu;  Jin-Wei Zhang;  Hui Wei;  Wen-Ling Ye;  Zhen-Ke Deng;  Lin Zhang;  Yan Cheng;  Defang Ouyang;  Qian Cao;  Dong-Sheng Cao
Favorite  |  View/Download:10/0  |  Submit date:2020/03/25
Hepatotoxicity  Adverse Hepatic Effects  Toxicity Risk Assessment  Sar  Random Forest  
A Comprehensive Map of FDA-Approved Pharmaceutical Products Journal article
PHARMACEUTICS, 2018,Volume: 10,Issue: 4
Authors:  Hao Zhong;  Ging Chan;  Yuanjia Hu;  Hao Hu;  Defang Ouyang
Favorite  |  View/Download:12/0  |  Submit date:2020/01/06
Drug Delivery System  Fda-approval Drugs  Generic Drugs  Oral Sustained-release Preparation  Inhalation  Complex Injection  Transdermal Patch  
HAMdb: a database of human autophagy modulators with specific pathway and disease information Journal article
JOURNAL OF CHEMINFORMATICS, 2018,Volume: 10
Authors:  Wang, Ning-Ning;  Dong, Jie;  Zhang, Lin;  Ouyang, Defang;  Cheng, Yan;  Chen, Alex F.;  Lu, Ai-Ping;  Cao, Dong-Sheng
Favorite  |  View/Download:25/0  |  Submit date:2018/10/30
Autophagy  Autophagy Modulator  Database  Disease  Pathophysiological  Pathway  
Analysis of the Literature and Patents on Solid Dispersions from 1980 to 2015 Journal article
MOLECULES, 2018,Volume: 23,Issue: 7
Authors:  Zhang, Jinglu;  Han, Run;  Chen, Weijie;  Zhang, Weixiang;  Li, Ying;  Ji, Yuanhui;  Chen, Lijiang;  Pan, Hao;  Yang, Xinggang;  Pan, Weisan;  Ouyang, Defang
Favorite  |  View/Download:20/0  |  Submit date:2018/10/30
Solid Dispersion  Big Data  Literature  Patent  Scientific Knowledge Mapping  Citespace  
Predicting oral disintegrating tablet formulations by neural network techniques Journal article
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018,Volume: 13,Issue: 4,Page: 336-342
Authors:  Han, Run;  Yang, Yilong;  Li, Xiaoshan;  Ouyang, Defang
Favorite  |  View/Download:23/0  |  Submit date:2018/10/30
Oral Disintegrating Tablets  Formulation Prediction  Artificial Neural Network  Deep Neural Network  Deep-learning