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Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
Authors:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li;  Xia Sun;  Qiu-Ling Chen;  Yi-Tao Wang;  Ying Wang;  Guo-Chun Zhou
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1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
Discovery of fused bicyclic derivatives of 1H-pyrrolo[1,2-c]imidazol-1-one as VDR signaling regulators Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2019,Volume: 27,Issue: 17,Page: 3879-3888
Authors:  Bin Xu;  Mo-Yu Ding;  Zhibing Weng;  Zheng-Qing Li;  Feng Li;  Xia Sun;  Qiu-Ling Chen;  Yi-Tao Wang;  Ying Wang;  Guo-Chun Zhou
Favorite  |  View/Download:8/0  |  Submit date:2020/05/05
1h-pyrrolo[1,2-c]Imidazol-1-one  Vitamin d Receptor (Vdr)  Autophagy  Apoptosis  
Andrographolide derivative ameliorates dextran sulfate sodium-induced experimental colitis in mice Journal article
BIOCHEMICAL PHARMACOLOGY, 2019,Volume: 163,Page: 416-424
Authors:  Bao-Jian Guo;  Zhuyun Liu;  Mo-Yu Ding;  Feng Li;  Mei Jing;  Li-Peng Xu;  Yu-Qiang Wang;  Zai-Jun Zhang;  Yitao Wang;  Decai Wang;  Guo-Chun Zhou;  Ying Wang
Favorite  |  View/Download:11/0  |  Submit date:2020/03/27
Andrographolide Analog  Colitis  Ibd  Nf-κb  Β-catenin  
Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice Journal article
BIOORGANIC & MEDICINAL CHEMISTRY, 2018,Volume: 26,Issue: 18,Page: 5053-5061
Authors:  Chen, Shao-Ru;  Li, Feng;  Ding, Mo-Yu;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Zhou, Guo-Chun;  Wang, Ying
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Andrographolide  Stat3 Inhibitor  Acute Liver Damage  Inflammation  
Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity Journal article
RSC ADVANCES, 2018,Volume: 8,Issue: 17,Page: 9440-9456
Authors:  Li, Feng;  Li, Xiao-Min;  Sheng, Dekuan;  Chen, Shao-Ru;  Nie, Xin;  Liu, Zhuyun;  Wang, Decai;  Zhao, Qi;  Wang, Yitao;  Wang, Ying;  Zhou, Guo-Chun
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Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-kappa B Signaling Pathway Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Nie, Xin;  Chen, Shao-Ru;  Wang, Kun;  Peng, Yuran;  Wang, Yi-Tao;  Wang, Decai;  Wang, Ying;  Zhou, Guo-Chun
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An andrographolide derivative AGP-26b exibitiing anti-angiogenic activity in HUVECs and zebrafish via blocking the VEGFA/VEGFR2 signaling pathway Journal article
MOLECULAR BIOSYSTEMS, 2017,Volume: 13,Issue: 3,Page: 525-536
Authors:  Huang, Bin;  Peng, Yuran;  Li, Jingjing;  Li, Shang;  Sun, Yicheng;  Wang, Decai;  Yang, Binrui;  Chan, Judy Yuet-Wa;  Yu, Huidong;  Leung, George Pak-Heng;  Hoi, Maggie Pui-Man;  Zhou, Guo-Chun;  Lee, Simon Ming-Yuen
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Anti-angiogenic activity of a new andrographolide derivative in zebrafish and HUVECs Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 344-353
Authors:  JingjingLia;  YuranPeng;  Shang Li;  Yicheng Sun;  Judy Yuet-Wa Chan;  Guozhen Cui;  Decai Wang;  Guo-Chun Zhou;  Simon Ming-Yuen Lee
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Andrographolide  Angiogenesis  Zebrafish  
Differential: In vitro and in vivo anti-angiogenic activities of acetal and ketal andrographolide derivatives in HUVEC and zebrafish models Journal article
RSC Advances, 2016,Volume: 6,Issue: 105,Page: 102831-102842
Authors:  Dekuan Sheng;  Jingjing Li;  Kun Wang;  Yuran Peng;  Shang Li;  Yicheng Sun;  Zhuyun Liu;  Decai Wang;  Simon Ming Yuen Lee;  Guo-Chun Zhou
Favorite  |  View/Download:11/0  |  Submit date:2018/11/06
SAR studies of 3,14,19-derivatives of andrographolide on anti-proliferative activity to cancer cells and toxicity to zebrafish: An in vitro and in vivo study Journal article
RSC Advances, 2015,Volume: 5,Issue: 29,Page: 22510-22526
Authors:  Yuran Peng;  Jingjing Li;  Yicheng Sun;  Judy Yuet-Wa Chan;  Dekuan Sheng;  Kun Wang;  Ping Wei;  Pingkai Ouyang;  Decai Wang;  Simon Ming Yuen Lee;  Guo-Chun Zhou
Favorite  |  View/Download:15/0  |  Submit date:2018/11/06