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Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9 Journal article
NATURE METHODS, 2019,Volume: 16,Issue: 8,Page: 722–730
Authors:  Gigi C. G. Choi;  Peng Zhou;  Chaya T. L. Yuen;  Becky K. C. Chan;  Feng Xu;  Siyu Bao;  Hoi Yee Chu;  Dawn Thean;  Kaeling Tan;  Koon Ho Wong;  Zongli Zheng;  Alan S. L. Wong
Favorite | View/Download:14/0 | TC[WOS]:4 TC[Scopus]:0 | Submit date:2020/05/21
Universal plasmids to facilitate gene deletion and gene tagging in filamentous fungi Journal article
FUNGAL GENETICS AND BIOLOGY, 2019,Volume: 125,Page: 28-35
Authors:  Longguang Qin;  Ang Li;  Kaeling Tan;  Shuhui Guo;  Yingying Chen;  Fang Wang;  Koon Ho Wong
Favorite | View/Download:7/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/21
Gene Deletion  Epitope Tagging  Selectable Markers  Plasmid Collection  Filamentous Fungi  Aspergillus  
Novel variants identified in multiple sclerosis patients from southern China Journal article
Frontiers in Neurology, 2018,Volume: 9
Authors:  Wang H.;  Pardeshi L.A.;  Rong X.;  Li E.;  Wong K.H.;  Peng Y.;  Xu R.-H.
Favorite | View/Download:18/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2018/12/20
Human Leucocyte Antigen  Multiple Sclerosis  Single Nucleotide Polymorphism  Triobp  Whole-exome Sequencing  
BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition Journal article
Oncogene, 2018,Issue: 37,Page: 6341–6356
Authors:  Baoyuan Zhang;  Junfang Lyu;  Yifan Liu;  Changjie Wu;  Eun Ju Yang;  Lakhansing Pardeshi;  Kaeling Tan;  Koon Ho Wong;  Qiang Chen;  Xiaoling Xu;  Chu-Xia Deng;  Joong Sup Shim
Favorite | View/Download:24/0 | TC[WOS]:2 TC[Scopus]:0 | Submit date:2018/12/17
Single-cell RNA-Seq reveals cell heterogeneity and hierarchy within mouse mammary epithelia Journal article
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018,Volume: 293,Issue: 22,Page: 8315-8329
Authors:  Sun, Heng;  Miao, Zhengqiang;  Zhang, Xin;  Chan, Un In;  Su, Sek Man;  Guo, Sen;  Wong, Chris Koon Ho;  Xu, Xiaoling;  Deng, Chu-Xia
Favorite | View/Download:49/0 | TC[WOS]:6 TC[Scopus]:0 | Submit date:2018/10/30
Mammary Gland  Development  Breast Cancer  Biomarker  Cell Differentiation  Stem Cells  cdh5+cell  Mammary Stem Cells (Mascs)  Single Cell Rna-seq  
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space Journal article
PLOS GENETICS, 2018,Volume: 14,Issue: 3
Authors:  Veri, Amanda O.;  Miao, Zhengqiang;  Shapiro, Rebecca S.;  Tebbji, Faiza;  O'Meara, Teresa R.;  Kim, Sang Hu;  Colazo, Juan;  Tan, Kaeling;  Vyas, Valmik K.;  Whiteway, Malcolm;  Robbins, Nicole;  Wong, Koon Ho;  Cowen, Leah E.
Favorite | View/Download:46/0 | TC[WOS]:11 TC[Scopus]:0 | Submit date:2018/10/30
The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation Journal article
NATURE COMMUNICATIONS, 2017,Volume: 8
Authors:  Xie, Jinglin L.;  Qin, Longguang;  Miao, Zhengqiang;  Grys, Ben T.;  Diaz, Jacinto De La Cruz;  Ting, Kenneth;  Krieger, Jonathan R.;  Tong, Jiefei;  Tan, Kaeling;  Leach, Michelle D.;  Ketela, Troy;  Moran, Michael F.;  Krysan, Damian J.;  Boone, Charles;  Andrews, Brenda J.;  Selmecki, Anna;  Wong, Koon Ho;  Robbins, Nicole;  Cowen, Leah E.
Favorite | View/Download:19/0 | TC[WOS]:16 TC[Scopus]:0 | Submit date:2018/10/30
Evidence that Mediator is essential for Pol II transcription, but is not a required component of the preinitiation complex in vivo Journal article
ELIFE, 2017,Volume: 6
Authors:  Petrenko, Natalia;  Jin, Yi;  Wong, Koon Ho;  Struhl, Kevin
Favorite | View/Download:19/0 | TC[WOS]:14 TC[Scopus]:0 | Submit date:2018/10/30
Spheroidal formation preserves human stem cells for prolonged time under ambient conditions for facile storage and transportation Journal article
BIOMATERIALS, 2017,Volume: 133,Page: 275-286
Authors:  Jiang, Bin;  Yan, Li;  Miao, Zhengqiang;  Li, Enqin;  Wong, Koon Ho;  Xu, Ren-He
Favorite | View/Download:27/0 | TC[WOS]:21 TC[Scopus]:0 | Submit date:2018/10/30
Stem Cells  Spheroids  Ambient  Hypothermia  Survival  
PBrowse: A web-based platform for real-time collaborative exploration of genomic data Journal article
Nucleic Acids Research, 2017,Volume: 45,Issue: 9
Authors:  Szot P.S.;  Yang A.;  Wang X.;  Parsania C.;  Rohm U.;  Wong K.H.;  Ho J.W.K.
Favorite | View/Download:6/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date:2019/01/16