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Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9 Journal article
NATURE METHODS, 2019,Volume: 16,Issue: 8,Page: 722–730
Authors:  Gigi C. G. Choi;  Peng Zhou;  Chaya T. L. Yuen;  Becky K. C. Chan;  Feng Xu;  Siyu Bao;  Hoi Yee Chu;  Dawn Thean;  Kaeling Tan;  Koon Ho Wong;  Zongli Zheng;  Alan S. L. Wong
Favorite  |  View/Download:13/0  |  Submit date:2020/05/21
Universal plasmids to facilitate gene deletion and gene tagging in filamentous fungi Journal article
FUNGAL GENETICS AND BIOLOGY, 2019,Volume: 125,Page: 28-35
Authors:  Longguang Qin;  Ang Li;  Kaeling Tan;  Shuhui Guo;  Yingying Chen;  Fang Wang;  Koon Ho Wong
Favorite  |  View/Download:7/0  |  Submit date:2020/05/21
Gene Deletion  Epitope Tagging  Selectable Markers  Plasmid Collection  Filamentous Fungi  Aspergillus  
BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition Journal article
Oncogene, 2018,Issue: 37,Page: 6341–6356
Authors:  Baoyuan Zhang;  Junfang Lyu;  Yifan Liu;  Changjie Wu;  Eun Ju Yang;  Lakhansing Pardeshi;  Kaeling Tan;  Koon Ho Wong;  Qiang Chen;  Xiaoling Xu;  Chu-Xia Deng;  Joong Sup Shim
Favorite  |  View/Download:23/0  |  Submit date:2018/12/17
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space Journal article
PLOS GENETICS, 2018,Volume: 14,Issue: 3
Authors:  Veri, Amanda O.;  Miao, Zhengqiang;  Shapiro, Rebecca S.;  Tebbji, Faiza;  O'Meara, Teresa R.;  Kim, Sang Hu;  Colazo, Juan;  Tan, Kaeling;  Vyas, Valmik K.;  Whiteway, Malcolm;  Robbins, Nicole;  Wong, Koon Ho;  Cowen, Leah E.
Favorite  |  View/Download:45/0  |  Submit date:2018/10/30
The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation Journal article
NATURE COMMUNICATIONS, 2017,Volume: 8
Authors:  Xie, Jinglin L.;  Qin, Longguang;  Miao, Zhengqiang;  Grys, Ben T.;  Diaz, Jacinto De La Cruz;  Ting, Kenneth;  Krieger, Jonathan R.;  Tong, Jiefei;  Tan, Kaeling;  Leach, Michelle D.;  Ketela, Troy;  Moran, Michael F.;  Krysan, Damian J.;  Boone, Charles;  Andrews, Brenda J.;  Selmecki, Anna;  Wong, Koon Ho;  Robbins, Nicole;  Cowen, Leah E.
Favorite  |  View/Download:19/0  |  Submit date:2018/10/30