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L-Tetrahydropalamatine Inhibits Tumor Necrosis Factor-α-Induced Monocyte-Endothelial Cell Adhesion through Downregulation of Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1 Involving Suppression of Nuclear Factor-κB Signaling Pathway Journal article
CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2015,Volume: 21,Issue: 5,Page: 361-368
Authors:  YANG Bin-rui;  YU Nan;  DENG Yan-hui;  HOI Pui Man;  YANG Bin;  LIU Guang-yu;  CONG Wei-hong;  Simon Ming-Yuen Lee
Favorite | View/Download:3/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/05/07
L-tetrahydropalmatine  Atherosclerosis  Cell Adhesion Molecules  Tumor Necrosis Factor-α  Nuclear Factor-κb  
L-tetrahydropalamatine inhibits tumor necrosis factor-alpha-induced monocyte-endothelial cell adhesion through downregulation of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 involving suppression of nuclear factor-kappa B signaling pathway Journal article
CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2015,Volume: 21,Issue: 5,Page: 361-368
Authors:  Bin-rui Yang;  Nan Yu;  Yan-hui Deng;  Pui Man Hoi;  Bin Yang;  Guang-yu Liu;  Wei-hong Cong;  Simon Ming-Yuen Lee
Favorite | View/Download:9/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2020/04/15
Nuclear Factor-kappa b  L-tetrahydropalmatine  Atherosclerosis  Cell Adhesion Molecules  Tumor Necrosis Factor-alpha  
Schisantherin A protects against 6-OHDA-induced dopaminergic neuron damage in zebrafish and cytotoxicity in SH-SY5Y cells through the ROS/NO and AKT/GSK3 β pathways Journal article
JOURNAL OF ETHNOPHARMACOLOGY, 2015,Volume: 170,Page: 8-15
Authors:  Lun Qing Zhang;  Fei Sa;  Cheong Meng Chong;  Ying Wang;  Zhong Yan Zhou;  Raymond Chuen Chung Chang;  Shun Wan Chan;  Pui Man Hoi;  Simon Ming Yuen Lee
Favorite | View/Download:4/0 | TC[WOS]:23 TC[Scopus]:0 | Submit date:2020/04/15
6-hydroxydopamine (6-ohda)  Oxidative Stress  Parkinson׳s Disease  Schisantherin a  
The Presystemic Interplay between Gut Microbiota and Orally Administered Calycosin-7-O-b-D-Glucoside Journal article
DRUG METABOLISM AND DISPOSITION, 2015,Volume: 43,Issue: 10,Page: 1601-1611
Authors:  Jian-Qing Ruan;  Shang Li;  Ya-Ping Li;  Wen-Jin Wu;  Simon Ming-Yuen Lee;  Ru Yan
Favorite | View/Download:7/0 | TC[WOS]:12 TC[Scopus]:0 | Submit date:2020/03/26
Zebrafish models of cardiovascular diseases and their applications in herbal medicine research Journal article
European journal of pharmacology, 2015,Volume: 768,Page: 77-86
Authors:  Sai-Wang Seto;  Hosen Kiat;  Simon M.Y. Lee;  Alan Bensoussan;  Yu-Ting Sun;  Maggie P.M. Hoi;  Dennis Chang
Favorite | View/Download:8/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2019/01/22
Zebrafish  Chinese Herbal Medicine  Cardiovascular  Animal Model  Review  
SAR studies of 3,14,19-derivatives of andrographolide on anti-proliferative activity to cancer cells and toxicity to zebrafish: An in vitro and in vivo study Journal article
RSC Advances, 2015,Volume: 5,Issue: 29,Page: 22510-22526
Authors:  Yuran Peng;  Jingjing Li;  Yicheng Sun;  Judy Yuet-Wa Chan;  Dekuan Sheng;  Kun Wang;  Ping Wei;  Pingkai Ouyang;  Decai Wang;  Simon Ming Yuen Lee;  Guo-Chun Zhou
Favorite | View/Download:15/0 | TC[WOS]:18 TC[Scopus]:0 | Submit date:2018/11/06
Study on the HPLC Chromatograms and Pro-Angiogenesis Activities of the Flowers of Panax notoginseng Journal article
Journal of Liquid Chromatography and Related Technologies, 2015,Volume: 38,Issue: 13,Page: 1286-1295
Authors:  Xie R.-F.;  Yang B.-R.;  Cheng P.-P.;  Wu S.;  Li Z.-C.;  Tang J.-Y.;  Li S.;  Tang N.;  Lee S.M.Y.;  Wang Y.-H.;  Zhou X.
Favorite | View/Download:5/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/11/06
Angiogenesis  Chromatograms  Flowerof Panax Notoginseng  Zebrafish  
Rhodamine B-conjugated encrypted vipericidin nonapeptide is a potent toxin to zebrafish and associated with in vitro cytotoxicity Journal article
Biochimica et Biophysica Acta - General Subjects, 2015,Volume: 1850,Issue: 6,Page: 1253-1260
Authors:  Liang Wang;  Judy Y.W. Chan;  Juciane V. Rêgo;  Cheong-Meng Chong;  Nana Ai;  Cláudio B. Falcão;  Gandhi Rádis-Baptista;  Simon M.Y. Lee
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Cell-penetrating Peptide  Cytotoxin  Encrypted Peptides  Rhodamine B-conjugated Peptide  Vipericidins  Zebra-fish Model  
Icaritin protects against oxidative stress-induced injury in cardiac H9c2 cells via Akt/Nrf2/HO-1 and calcium signalling pathways Journal article
Journal of Functional Foods, 2015,Volume: 18,Page: 213-223
Authors:  Si Wan Lei;  Guozhen Cui;  George Pak Heng Leung;  Sharon Chui Wah Luk;  Maggie Pui Man Hoi;  Liang Wang;  Gail B. Mahady;  Simon Ming Yuen Lee
Favorite | View/Download:10/0 | TC[WOS]:7 TC[Scopus]:0 | Submit date:2018/11/06
Calcium Ion  Cardiac H9c2 Cells  Icaritin  Nf-e2-related Factor 2  Oxidative Stress  
Basal Flt1 tyrosine kinase activity is a positive regulator of endothelial survival and vascularization during zebrafish embryogenesis Journal article
Biochimica et Biophysica Acta - General Subjects, 2015,Volume: 1850,Issue: 2,Page: 373-384
Authors:  Li S.;  Zhou X.L.;  Dang Y.Y.;  Kwan Y.W.;  Chan S.W.;  Leung G.P.H.;  Lee S.M.-Y.;  Hoi M.P.M.
Favorite | View/Download:7/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/11/06
Calycosin  Endothelial Cell  Flt1  Molecular Docking  Vegf Receptor Inhibitor  Zebrafish  
Cytoprotection of baicalein against oxidative stress-induced cardiomyocytes injury through the Nrf2/Keap1 pathway Journal article
Journal of Cardiovascular Pharmacology, 2015,Volume: 65,Issue: 1,Page: 39-46
Authors:  Cui, Guozhen;  Chui Wah Luk, Sharon;  Li, Ronald Adolphus;  Chan, Ken Kwok Keung;  Lei, Si Wan;  Wang, Liang;  Shen, Huifang;  Leung, George Pak Heng;  Lee, Simon Ming Yuen
Favorite | View/Download:10/0 | TC[WOS]:27 TC[Scopus]:0 | Submit date:2018/11/06
Baicalein  Cardioprotection  Nrf2  Oxidative Stress  
Protective Effect of Edaravone in Primary Cerebellar Granule Neurons against Iodoacetic Acid-Induced Cell Injury Journal article
Oxidative Medicine and Cellular Longevity, 2015,Volume: 2015
Authors:  Xinhua Zhou;  Longjun Zhu;  Liang Wang;  Baojian Guo;  Gaoxiao Zhang;  Yewei Sun;  Zaijun Zhang;  Simon Ming-Yuen Lee;  Pei Yu;  Yuqiang Wang
Favorite | View/Download:11/0 | TC[WOS]:5 TC[Scopus]:0 | Submit date:2018/11/06
Cortex Fraxini (Qingpi) Protects Rat Pheochromocytoma Cells against 6-Hydroxydopamine-Induced Apoptosis Journal article
Parkinson's Disease, 2015,Volume: 2015
Authors:  Jing-Jie Li;  Shi-Ya Zhou;  Huan Zhang;  Kim-Hung Lam;  Simon Ming-Yuen Lee;  Peter Hoi-Fu Yu;  Shun-Wan Chan
Favorite | View/Download:7/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/11/06
Recent advances in structure-based drug design and virtual screening of VEGFR tyrosine kinase inhibitors Journal article
Methods, 2015,Volume: 71,Issue: C,Page: 85-91
Authors:  Pui Man Hoi;  Shang Li;  Chi Teng Vong;  Hisa Hui Ling Tseng;  Yiu Wa Kwan;  Simon Ming-Yuen Lee
Favorite | View/Download:16/0 | TC[WOS]:15 TC[Scopus]:0 | Submit date:2018/11/06
Molecular Docking  Pharmacophore Modeling  Vegfr2  Vegfr2 Inhibitors  Virtual Screening  
Pharmacokinetic study and optimal formulation of new anti-parkinson natural compound schisantherin A Journal article
Parkinson's Disease, 2015,Volume: 2015
Authors:  Fei Sa;  Bao Jian Guo;  Sai Li;  Zai Jun Zhang;  Hok Man Chan;  Ying Zheng;  Simon Ming Yuen Lee
Favorite | View/Download:13/0 | TC[WOS]:8 TC[Scopus]:0 | Submit date:2018/11/06
A versatile reversed phase-strong cation exchange-reversed phase (RP-SCX-RP) multidimensional liquid chromatography platform for qualitative and quantitative shotgun proteomics Journal article
Analyst, 2015,Volume: 140,Issue: 4,Page: 1237-1252
Authors:  Henry C. H. Law;  Ricky P. W. Kong;  Samuel S. W. Szeto;  Yun Zhao;  Zaijun Zhang;  Yuqiang Wang;  Guohui Li;  Quan Quan;  Simon M. Y. Lee;  Herman C. Lama;  Ivan K. Chu
Favorite | View/Download:15/0 | TC[WOS]:13 TC[Scopus]:0 | Submit date:2018/11/06
Synthesis and relationship of stability and biological activity of new DSS and TMP conjugates Journal article
MedChemComm, 2015,Volume: 6,Issue: 4,Page: 586-591
Authors:  Yewei Sun;  Zicheng Tan;  Zhibin Liang;  Liang Wang;  Luchen Shan;  Pei Yu;  Simon MingYuen Lee;  Yuqiang Wang
Favorite | View/Download:13/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/11/06
Transcriptome analysis of leaves, roots and flowers of Panax notoginseng identifies genes involved in ginsenoside and alkaloid biosynthesis Journal article
BMC Genomics, 2015,Volume: 16,Issue: 1
Authors:  Ming-Hua Liu;  Bin-Rui Yang;  Wai-Fung Cheung;  Kevin Yi Yang;  He-Feng Zhou;  Jamie Sui-Lam Kwok;  Guo-Cheng Liu;  Xiao-Feng Li;  Silin Zhong;  Simon Ming-Yuen Lee;  Stephen Kwok-Wing Tsui
Favorite | View/Download:8/0 | TC[WOS]:44 TC[Scopus]:0 | Submit date:2018/11/06
Ginsenosides  Panax Notoginseng  Transcriptome  
Discovery of novel anti-parkinsonian effect of schisantherin A in in vitro and in vivo Journal article
Neuroscience Letters, 2015,Volume: 593,Page: 7-12
Authors:  Fei Sa;  Lun Qing Zhang;  Cheong Meng Chong;  Bao Jian Guo;  Sai Li;  Zai Jun Zhang;  Ying Zheng;  Pui Man Hoi;  Simon Ming Yuen Lee
Favorite | View/Download:22/0 | TC[WOS]:18 TC[Scopus]:0 | Submit date:2018/11/06
Bcl-2  Dibenzocyclooctadiene Lignans  Neuroprotection  Schisantherin a  
Relaxation effect of abacavir on rat basilar arteries Journal article
PLoS ONE, 2015,Volume: 10,Issue: 4
Authors:  Rachel Wai Sum Li;  Cui Yang;  Shun Wan Chan;  Maggie Pui Man Hoi;  Simon Ming Yuen Lee;  Yiu Wa Kwan;  George Pak Heng Leung
Favorite | View/Download:7/0 | TC[WOS]:3 TC[Scopus]:0 | Submit date:2018/11/06