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| Discovery of a novel ROCK2 inhibitor with anti-migration effects via docking and high-content drug screening Journal article
MOLECULAR BIOSYSTEMS, 2016,Volume: 12,Issue: 9,Page: 2713-2721
Authors: Cheong-Meng Chong; Man-Teng Kou; Peichen Pan; Hefeng Zhou; Nana Ai; Chuwen Li; Hai-Jing Zhong; Chung-Hang Leung ; Tingjun Hou; Simon Ming-Yuen Lee
  Favorite | View/Download：12/0 | TC[WOS]:4 TC[Scopus]:5 | Submit date：2020/07/30 |
| MITOCHONDRIA AS A THERAPEUTIC TARGET FOR ALZHEIMER'S DISEASE Book chapter
出自: FUNCTIONS, DISEASE-RELATED DYSFUNCTIONS, AND THERAPEUTIC TARGETING OF NEURONAL MITOCHONDRIA:JOHN WILEY & SONS INC, 111 RIVER ST, HOBOKEN, NJ 07030 USA, 2016, 页码:
322-338
Authors: Hung, Clara Hiu-Ling; Cheng, Sally Shuk-Yee; Lee, Simon Ming-Yuen; Chang, Raymond Chuen-Chung
Favorite | View/Download：248/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date：2020/01/16 |
| No synergism between bis(propyl)-cognitin and rasagiline on protecting dopaminergic neurons in Parkinson's disease mice Journal article
NEURAL REGENERATION RESEARCH, 2016,Volume: 11,Issue: 8,Page: 1339-1346
Authors: Cheng-you Zheng; Bao-jian Guo; Wei Cai; Wei Cui; Shing-hung Mak; Yu-qiang Wang; Simon Ming-yuen Lee; Yi-fan Han; Zai-jun Zhang
Favorite | View/Download：248/0 | TC[WOS]:1 TC[Scopus]:0 | Submit date：2020/01/16
Nerve Regeneration Parkinson's Disease Bis(Propyl)-cognitin Rasagiline Monoamine Oxidase b Dopamine Multitarget Synergism Neuroprotection Neural Regeneration |
| Potent Protection Against MPP+ -Induced Neurotoxicity via Activating Transcription Factor MEF2D by a Novel Derivative of Naturally Occurring Danshensu/Tetramethylpyrazine Journal article
NEUROMOLECULAR MEDICINE, 2016,Volume: 18,Issue: 4,Page: 561-572
Authors: Shengquan Hu; Liang Wang; Shinghung Mak; Zaijun Zhang; Daping Xu; Haitao Li; Yide Li; Yuanjia Hu; Simon Ming Yuen Lee; Yuqiang Wang; Yifan Han
Favorite | View/Download：249/0 | TC[WOS]:5 TC[Scopus]:6 | Submit date：2020/01/16
Parkinson’s Disease Mef2d Neuroprotection |
| 中藥評質量價關鍵科學問題的基礎研究及其應用 Scientific research award
省级科研奖励等: 二等
Authors: 王一濤; 李紹平; 李銘源; 梁重恒; 王春明
Favorite | View/Download：19/0 | TC[WOS]:0 TC[Scopus]:0 | Submit date：2019/01/16 |
| A Novel Danshensu Derivative Prevents Cardiac Dysfunction and Improves the Chemotherapeutic Efficacy of Doxorubicin in Breast Cancer Cells Journal article
Journal of Cellular Biochemistry, 2016,Volume: 117,Issue: 1,Page: 94-105
Authors: Liang Wang; Xiaojing Zhang; Judy Yuet‐Wa Chan; Luchen Shan; Guozhen Cui; Qingbin Cui; Yingfei Wang; Jingjing Li; Huanxian Chen; Qingwen Zhang; Pei Yu; Yifan Han; Yuqiang Wang; Simon Ming‐Yuen Lee
Favorite | View/Download：17/0 | TC[WOS]:17 TC[Scopus]:20 | Submit date：2018/11/06
Breast Cancer Cardiotoxicity Doxorubicin Mitochondrial Biogenesis |
| The transcriptome of the zoanthid protopalythoa variabilis (cnidaria, anthozoa) predicts a basal repertoire of toxin-like and venom-Auxiliary polypeptides Journal article
Genome Biology and Evolution, 2016,Volume: 8,Issue: 9,Page: 3045-3064
Authors: Chen Huang; Jean-Étienne RL Morlighem; Hefeng Zhou; Érica P Lima; Paula B Gomes; Jing Cai; Inchio Lou; Carlos D Pérez; Simon Ming Lee; Gandhi Rádis-Baptista
Favorite | View/Download：8/0 | TC[WOS]:19 TC[Scopus]:22 | Submit date：2018/11/06
Hexacorallia Molecular Toxinology Peptide Toxin Rna-seq Transcriptome Venomics Zoanthidea |
| FGF2 Prevents Sunitinib-Induced Cardiotoxicity in Zebrafish and Cardiomyoblast H9c2 Cells Journal article
Cardiovascular Toxicology, 2016,Volume: 16,Issue: 1,Page: 46-53
Authors: Guozhen Cui; Huanxian Chen; Wei Cui; Xiaogang Guo; Jiansong Fang; Ailin Liu; Yonglong Chen; Simon Ming Yuen Lee
Favorite | View/Download：8/0 | TC[WOS]:11 TC[Scopus]:12 | Submit date：2018/11/06
Cardiotoxicity Fgf2 Plc-γ/c-raf/creb Sunitinib Zebrafish |
| Inhibition of human equilibrative nucleoside transporters by 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine Journal article
European Journal of Pharmacology, 2016,Volume: 791,Page: 544-551
Authors: Tang P.C.T.; Yang C.; Li R.W.-S.; Lee S.M.-Y.; Hoi M.P.-M.; Chan S.-W.; Kwan Y.-W.; Tse C.-M.; Leung G.P.-H.
Favorite | View/Download：18/0 | TC[WOS]:4 TC[Scopus]:7 | Submit date：2018/11/06
Cancer Cardiovascular Disease Equilibrative Nucleoside Transporters Inhibitor |
| Anti-angiogenic activity of a new andrographolide derivative in zebrafish and HUVECs Journal article
European Journal of Pharmacology, 2016,Volume: 789,Page: 344-353
Authors: JingjingLia; YuranPeng; Shang Li; Yicheng Sun; Judy Yuet-Wa Chan; Guozhen Cui; Decai Wang; Guo-Chun Zhou; Simon Ming-Yuen Lee
Favorite | View/Download：10/0 | TC[WOS]:12 TC[Scopus]:13 | Submit date：2018/11/06
Andrographolide Angiogenesis Zebrafish |
| Differential: In vitro and in vivo anti-angiogenic activities of acetal and ketal andrographolide derivatives in HUVEC and zebrafish models Journal article
RSC Advances, 2016,Volume: 6,Issue: 105,Page: 102831-102842
Authors: Dekuan Sheng; Jingjing Li; Kun Wang; Yuran Peng; Shang Li; Yicheng Sun; Zhuyun Liu; Decai Wang; Simon Ming Yuen Lee; Guo-Chun Zhou
Favorite | View/Download：13/0 | TC[WOS]:5 TC[Scopus]:8 | Submit date：2018/11/06 |
| Calycosin and Formononetin Induce Endothelium-Dependent Vasodilation by the Activation of Large-Conductance Ca2+-Activated K+ Channels (BKCa) Journal article
Evidence-based Complementary and Alternative Medicine, 2016,Volume: 2016
Authors: Tseng H.H.L.; Vong C.T.; Leung G.P.-H.; Seto S.W.; Kwan Y.W.; Lee S.M.-Y.; Hoi M.P.M.
Favorite | View/Download：9/0 | TC[WOS]:2 TC[Scopus]:5 | Submit date：2018/11/06 |
| Genome-guided Investigation of Antibiotic Substances produced by Allosalinactinospora lopnorensis CA15-2T from Lop Nor region, China Journal article
Scientific Reports, 2016,Volume: 6
Authors: Huang C.; Leung R.K.-K.; Guo M.; Tuo L.; Guo L.; Yew W.W.; Lou I.; Lee S.M.Y.; Sun C.
Favorite | View/Download：18/0 | TC[WOS]:4 TC[Scopus]:5 | Submit date：2018/11/06 |
| Antrodia camphorata increases insulin secretion and protects from apoptosis in MIN6 cells Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: MAR
Authors: Chi Teng Vong; Hisa Hui Ling Tseng; Yiu Wa Kwan; Simon Ming-Yuen Lee; Maggie Pui Man Hoi
Favorite | View/Download：9/0 | TC[WOS]:4 TC[Scopus]:4 | Submit date：2018/11/06
Antrodia Camphorata Insulin Secretion Pancreatic Β-cell Death Ppar-γ Type 2 Diabetes Mellitus |
| Transport Mechanism of Coumarin 6 Nanocrystals with Two Particle Sizes in MDCKII Monolayer and Larval Zebrafish Journal article
ACS Applied Materials and Interfaces, 2016,Volume: 8,Issue: 20,Page: 12620-12630
Authors: Xiaoqing Miao; Ye Li; Xueqing Wang; Simon Ming-Yuen Lee; Ying Zheng
Favorite | View/Download：10/0 | TC[WOS]:24 TC[Scopus]:28 | Submit date：2018/11/06
Epithelial Cells Nanocrystals Particle Size Transport Mechanism Zebrafish |
| A novel agent exerts antitumor activity in breast cancer cells by targeting mitochondrial complex II Journal article
Oncotarget, 2016,Volume: 7,Issue: 22,Page: 32054-32064
Authors: Wang L.; Zhang X.; Cui G.; Chan J.Y.-W.; Wang L.; Li L.; Shan L.; Xu C.; Zhang Q.; Wang Y.; Di L.; Lee S.M.-Y.
Favorite | View/Download：15/0 | TC[WOS]:20 TC[Scopus]:27 | Submit date：2018/11/06
Breast Cancer Danshensu Mitochondrial Complex Ii Reactive Oxygen Species Tetramethylpyrazine |
| Multifunction of chrysin in Parkinson's model: Anti-neuronal apoptosis, neuroprotection via activation of MEF2D, and inhibition of monoamine oxidase-B Journal article
Journal of Agricultural and Food Chemistry, 2016,Volume: 64,Issue: 26,Page: 5324-5333
Authors: Baojian Guo; Chengyou Zheng; Wei Cai; Jiehong Cheng; Hongyu Wang; Haitao Li; Yewei Sun; Wei Cui; Yuqiang Wang; Yifan Han; Simon Ming-Yuen Lee; Zaijun Zhang
Favorite | View/Download：24/0 | TC[WOS]:11 TC[Scopus]:20 | Submit date：2018/11/06
Chrysin Mao-b Mef2d Neuroprotection Parkinson's Disease |
| Discovery, synthesis, and functional characterization of a novel neuroprotective natural product from the fruit of alpinia oxyphylla for use in Parkinson's disease through LC/MS-based multivariate data analysis-guided fractionation Journal article
Journal of Proteome Research, 2016,Volume: 15,Issue: 8,Page: 2595-2606
Authors: Guohui Li; Zaijun Zhang; Quan Quan; Renwang Jiang; Samuel S.W. Szeto; Shuai Yuan; Wing-tak Wong; Herman H. C. Lam; Simon Ming-Yuen Lee; Ivan K. Chu
Favorite | View/Download：14/0 | TC[WOS]:16 TC[Scopus]:17 | Submit date：2018/11/06
Natural Products Neuroprotective Nrf2 Parkinson's Disease Proteomics |
| A novel agent enhances the chemotherapeutic efficacy of doxorubicin in MCF-7 breast cancer cells Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: AUG
Authors: Wang L.; Chan J.Y.; Zhou X.; Cui G.; Yan Z.; Wang L.; Yan R.; Di L.; Wang Y.; Hoi M.P.; Shan L.; Lee S.M.
Favorite | View/Download：16/0 | TC[WOS]:8 TC[Scopus]:10 | Submit date：2018/11/06
Breast Cancer Danshensu Doxorubicin Glycolysis Grp78 Protein Tetramethylpyrazine |
| Discovery of a novel ROCK2 inhibitor with anti-migration effects: Via docking and high-content drug screening Journal article
Molecular BioSystems, 2016,Volume: 12,Issue: 9,Page: 2713-2721
Authors: Cheong-Meng Chong; Man-Teng Kou; Peichen Pan; Hefeng Zhou; Nana Ai; Chuwen Li; Hai-Jing Zhong; Chung-Hang Leung; Tingjun Hou; Simon Ming-Yuen Lee
Favorite | View/Download：15/0 | TC[WOS]:4 TC[Scopus]:5 | Submit date：2018/11/06 |
