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A two-step strategy for simultaneous dual-mode detection of methyl-paraoxon and Ni (Ⅱ)
Luo, Mai2; Chen, Ling2; Wei, Jinchao1,2; Cui, Xiping2; Cheng, Zehua2; Wang, Ting2; Chao, Incheng2; Zhao, Yunyang4; Gao, Hao1; Li, Peng2,3
2022-07-01
Source PublicationEcotoxicology and Environmental Safety
ISSN0147-6513
Volume239
Abstract

Exogenous pollution of Chinese medicinal materials by pesticide residues and heavy metal ions has attracted great attention. Relying on the rapid development of nanotechnology and multidisciplinary fields, fluorescent techniques have been widely applied in contaminant detection and pollution monitoring due to their advantages of simple preparation, low cost, high throughput and others. Most importantly, synchronous detection of multi-targets has always been pursued as one of the major goals in the design of fluorescent probes. Herein, we firstly develop a simultaneous sensing method for methyl-paraoxon (MP) and Nickel ion (Ni, Ⅱ) by using carbon based fluorescent nanocomposite with ratiometric signal readout and nanozyme. Notably, the designed system showed excellent effectiveness even when the two pollutants co-exist. Under the optimum conditions, this method provides low limits of detection of 1.25 µM for methyl-paraoxon and 0.01 µM for Ni (Ⅱ). To further verify the reliability, recovery studies of these two analytes were performed on ginseng radix et rhizoma, nelumbinis semen, and water samples. In addition, smartphone-based visual analysis has been introduced to expand its applicability in point of care detection. This work not only expands the application of the dual-mode approach to pollutant detection, but also provides insights into the analysis of multiple pollutants in a single assay.

KeywordDual-mode Methyl-paraoxon Nickel Ion Ratiometric Detection Visual Analysis
DOI10.1016/j.ecoenv.2022.113668
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaEnvironmental Sciences & Ecology ; Toxicology
WOS SubjectEnvironmental Sciences ; Toxicology
WOS IDWOS:000817779300006
Scopus ID2-s2.0-85130520269
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Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorWei, Jinchao; Gao, Hao; Li, Peng
Affiliation1.International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China, Jinan University, Guangzhou 510632, China
2.State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, 999078, China
3.Department of Pharmaceutical Sciences, Faculty of Health Sciences, University of Macau, Macau, 999078, China
4.Scientific Research Center, Wenzhou Medical University, Wenzhou, 325035, China
First Author AffilicationInstitute of Chinese Medical Sciences
Corresponding Author AffilicationInstitute of Chinese Medical Sciences;  Faculty of Health Sciences
Recommended Citation
GB/T 7714
Luo, Mai,Chen, Ling,Wei, Jinchao,et al. A two-step strategy for simultaneous dual-mode detection of methyl-paraoxon and Ni (Ⅱ)[J]. Ecotoxicology and Environmental Safety,2022,239.
APA Luo, Mai,Chen, Ling,Wei, Jinchao,Cui, Xiping,Cheng, Zehua,Wang, Ting,Chao, Incheng,Zhao, Yunyang,Gao, Hao,&Li, Peng.(2022).A two-step strategy for simultaneous dual-mode detection of methyl-paraoxon and Ni (Ⅱ).Ecotoxicology and Environmental Safety,239.
MLA Luo, Mai,et al."A two-step strategy for simultaneous dual-mode detection of methyl-paraoxon and Ni (Ⅱ)".Ecotoxicology and Environmental Safety 239(2022).
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