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An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine.
Li, S.; Jiang, N; Zhao, W; Ding, YF; Zheng, Y; Wang , L.H.; Zheng, J.; Wang, R.
2017-05-30
Source PublicationChemical Communications
ISSN1364-548X
Pages5870-5873
Abstract

We report an unprecedented, eco-friendly, in situ activatable model antibiotic, phenylalanyl-polyethylenimine (PhePEI), to potentially diminish antibiotic pollution of the environment and associated antibiotic resistance. The inactive PhePEI can be reversibly activated upon supramolecular crosslinking by cucurbit[8]uril, conferring potent antibacterial activity.

KeywordActivatable Antibiotic Cucurbit[8]Uril Supramolecular Crosslinking Polyethylenimine.
Language英語English
The Source to ArticlePB_Publication
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorZheng, J.; Wang, R.
Recommended Citation
GB/T 7714
Li, S.,Jiang, N,Zhao, W,et al. An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine.[J]. Chemical Communications,2017:5870-5873.
APA Li, S.,Jiang, N,Zhao, W,Ding, YF,Zheng, Y,Wang , L.H.,Zheng, J.,&Wang, R..(2017).An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine..Chemical Communications,5870-5873.
MLA Li, S.,et al."An eco-friendly in situ activatable antibiotic via cucurbit[8]uril-mediated supramolecular crosslinking of branched polyethylenimine.".Chemical Communications (2017):5870-5873.
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