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Recent advances in the managements of type 2 diabetes mellitus and natural hypoglycemic substances
Ning, Chong1; Jiao, Yuhan1; Wang, Jiaqi1; Li, Weiwei1; Zhou, Jingqiu1; Lee, Yi Chieh2; Ma, Dik Lung3; Leung, Chung Hang4; Zhu, Rugang1; David Wang, Hui Min5,6,7
2022-09-01
Source PublicationFood Science and Human Wellness
Volume11Issue:5Pages:1121-1133
Abstract

Diabetes has become a global concern at present, among which type 2 diabetes mellitus (T2DM) accounts for approximately 90 %–95 % of patients. T2DM is a type of metabolic disorder syndrome that results from a genetic defect, and it is based on insulin resistance and an insulin secretion disorder. The occurrence of T2DM is usually the outcome of both genetic and environmental factors and their interactions. The etiology and pathogenesis of diabetes have not been fully elucidated, and no radical therapeutic cure has been found. Patients with T2DM suffer from complications such as the development of a chronic hyperglycemic condition and even serious metabolic disorders and organ damage in the body and depression and dementia, in addition to other chronic complications. Many studies have suggested that diet is crucial in the development of diabetes and the control of blood glucose. Natural substances have the characteristics of low toxicity and few side effects and may be key to the development of diabetic health products and preventive treatments. This paper reviews the etiology, pathogenesis, risks, treatments and diets related to T2DM to summarize the types of recently available natural products, from both local and foreign sources, for lowering blood glucose at home and their application in supplementary hypoglycemic foods. The key findings and conclusions suggest that there are various known T2DM-inducing factors, including genetic and environmental factors and three types of hybrid factors.

KeywordDiet Etiological Agent Insulin Resistance Natural Substances Obesity Type 2 Diabetes Mellitus
DOI10.1016/j.fshw.2022.04.004
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaFood Science & Technology ; Nutrition & Dietetics
WOS IDWOS:000819122400004
Scopus ID2-s2.0-85132366516
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Cited Times [WOS]:0   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Corresponding AuthorZhu, Rugang; David Wang, Hui Min
Affiliation1.College of Light Industry, Liaoning University, Shenyang, 110036, China
2.Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan, 402, China
3.Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, 999077, China
4.State Key Laboratoryof Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, 999078, China
5.Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, Taiwan, 402, China
6.Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan, 807, China
7.Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung City, Taiwan, 404, China
Recommended Citation
GB/T 7714
Ning, Chong,Jiao, Yuhan,Wang, Jiaqi,et al. Recent advances in the managements of type 2 diabetes mellitus and natural hypoglycemic substances[J]. Food Science and Human Wellness,2022,11(5):1121-1133.
APA Ning, Chong,Jiao, Yuhan,Wang, Jiaqi,Li, Weiwei,Zhou, Jingqiu,Lee, Yi Chieh,Ma, Dik Lung,Leung, Chung Hang,Zhu, Rugang,&David Wang, Hui Min.(2022).Recent advances in the managements of type 2 diabetes mellitus and natural hypoglycemic substances.Food Science and Human Wellness,11(5),1121-1133.
MLA Ning, Chong,et al."Recent advances in the managements of type 2 diabetes mellitus and natural hypoglycemic substances".Food Science and Human Wellness 11.5(2022):1121-1133.
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