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Metal Graphitic Nanocapsules for Theranostics in Harsh Conditions
Yang, Yanxia1; Li, Shengkai1; Bu, Hongxiu1; Xia, Xin1; Chen, Long2; Xu, Yiting3; Chen, Zhuo1
2022-05-13
Source PublicationFrontiers in Chemistry
Volume10
Abstract

Metal nanoparticles (NPs) with superior physicochemical properties and biocompatibility have shown great potential in theranostics. However, metal NPs show poor stability in some harsh conditions such as strong acid, oxidation, corrosion and high-temperature conditions, which limits their extensive bioapplications. To address such issue, a variety of superstable metal graphitic nanocapsules with the metal cores confined in the nanospace of few-layer graphitic shell have been developed for biodetection and therapy in harsh conditions. In this mini-review, we summarize the recent advances in metal graphitic nanocapsules for bioapplications in harsh conditions. Firstly, their theranostic performance in non-intrinsic physiological harsh environment, including oxidation, corrosion and high-temperature conditions, is systematically discussed. Then, we highlight their theranostic performance in the harsh stomach condition that is strong acidic and pepsin-rich. It is expected that this review will offer inspiration to facilitate the exploitation of novel theranostic agents that are stable in harsh conditions.

KeywordGastric Environment Harsh Condition Metal Graphitic Nanocapsules Stability Theranostics
DOI10.3389/fchem.2022.909110
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000806064100001
Scopus ID2-s2.0-85131326043
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Cited Times [WOS]:0   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionDEPARTMENT OF COMPUTER AND INFORMATION SCIENCE
Corresponding AuthorChen, Zhuo
Affiliation1.Aptamer Engineering Center of Hunan Province, Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Bio–Sensing and Chemometrics, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology,Hunan University, Changsha,
2.Faculty of Science and Technology, University of Macau, Macao
3.Key Laboratory of Theoretical Organic Chemistry and Function Molecule, Ministry of Education, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan, China
Recommended Citation
GB/T 7714
Yang, Yanxia,Li, Shengkai,Bu, Hongxiu,et al. Metal Graphitic Nanocapsules for Theranostics in Harsh Conditions[J]. Frontiers in Chemistry,2022,10.
APA Yang, Yanxia,Li, Shengkai,Bu, Hongxiu,Xia, Xin,Chen, Long,Xu, Yiting,&Chen, Zhuo.(2022).Metal Graphitic Nanocapsules for Theranostics in Harsh Conditions.Frontiers in Chemistry,10.
MLA Yang, Yanxia,et al."Metal Graphitic Nanocapsules for Theranostics in Harsh Conditions".Frontiers in Chemistry 10(2022).
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