UM  > Faculty of Science and Technology
Affiliated with RCfalse
Status已發表Published
Magnetic Mobile Microrobots for Upstream and Downstream Navigation in Biofluids with Variable Flow Rate
Wu, Zehao1; Zhang, Yuting1; Ai, Nana2; Chen, Haoran1; Ge, Wei2; Xu, Qingsong1
2022-07
Source PublicationAdvanced Intelligent Systems
Volume4Issue:7Pages:2100266
Abstract

Magnetic mobile microrobots navigating biofluids with both upstream and downstream locomotion provide a promising solution to targeted drug delivery for precision medicine. However, the biofluid environment in blood vessels is complicated due to variations in flow rate and direction. It is still unknown how to make magnetic microrobots resist the variable flow rate in biofluids with both upstream and downstream locomotion. Herein, magnetic microrobots with various shapes and sizes have been controlled to navigate diverse biofluids under different flow rates and directions. Simulation and experimental studies have been conducted to analyze the influences of microrobot size and shape on translational velocity in confined microchannels filled with biofluids. A strategy is proposed to choose the optimized parameters of rotating magnetic field actuation for precise delivery of microrobots in a microfluidic chip, which contains a complex biofluid environment with variable flow rate and direction. The results are validated using various microrobots navigating the microfluidic chip and the yolks of zebrafish larvae in vivo. This work provides a guideline for selecting desirable microrobot dimensions and magnetic field actuation parameters for controllable navigation of magnetic mobile microrobots in complex biofluid flows.

KeywordMicrorobotics
DOI10.1002/aisy.202100266
URLView the original
Indexed BySCIE
Language英語English
Fulltext Access
Citation statistics
Cited Times [WOS]:4   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Science and Technology
Faculty of Health Sciences
DEPARTMENT OF ELECTROMECHANICAL ENGINEERING
Corresponding AuthorGe, Wei; Xu, Qingsong
Affiliation1.Department of Electromechanical Engineering, Faculty of Science and Technology, University of Macau, Avenida da Universidade, Taipa, Macau, China
2.Centre of Reproduction, Development and Aging, Faculty of Health Sciences, University of Macau, Taipa, Macau, China
First Author AffilicationFaculty of Science and Technology
Corresponding Author AffilicationCentre of Reproduction, Development and Aging;  Faculty of Science and Technology
Recommended Citation
GB/T 7714
Wu, Zehao,Zhang, Yuting,Ai, Nana,et al. Magnetic Mobile Microrobots for Upstream and Downstream Navigation in Biofluids with Variable Flow Rate[J]. Advanced Intelligent Systems,2022,4(7):2100266.
APA Wu, Zehao,Zhang, Yuting,Ai, Nana,Chen, Haoran,Ge, Wei,&Xu, Qingsong.(2022).Magnetic Mobile Microrobots for Upstream and Downstream Navigation in Biofluids with Variable Flow Rate.Advanced Intelligent Systems,4(7),2100266.
MLA Wu, Zehao,et al."Magnetic Mobile Microrobots for Upstream and Downstream Navigation in Biofluids with Variable Flow Rate".Advanced Intelligent Systems 4.7(2022):2100266.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wu, Zehao]'s Articles
[Zhang, Yuting]'s Articles
[Ai, Nana]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wu, Zehao]'s Articles
[Zhang, Yuting]'s Articles
[Ai, Nana]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wu, Zehao]'s Articles
[Zhang, Yuting]'s Articles
[Ai, Nana]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.