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Suicidality in clinically stable bipolar disorder and schizophrenia patients during the COVID-19 pandemic
Li, Yu Chen1; Bai, Wei2,3,4; Cai, Hong2,3,4; Wu, Yuxuan5,6; Zhang, Ling7; Ding, Yan Hong8; Yang, Juan Juan9,10; Du, Xiangdong6; Zeng, Zhen Tao7; Lu, Chang Mou7; Feng, Ke Xin11; Mi, Wen Fang8; Zhang, Lan8; Liu, Huan Zhong9,10; Balbuena, Lloyd12; Cheung, Teris13; Su, Zhaohui14; An, Feng Rong15; Xiang, Yu Tao1,2,3
Source PublicationTranslational Psychiatry

The coronavirus disease 2019 (COVID-19) pandemic has a disproportionate impact on vulnerable subpopulations, including those with severe mental illness (SMI). This study examined the one-year prevalence of suicidal ideation (SI), suicide plans (SP), and suicide attempts (SA) in bipolar disorder (BD) and schizophrenia (SCZ) patients during the pandemic. Prevalence rates were compared between the two disorders and associated factors were examined. A survey was conducted in six tertiary psychiatric hospitals and psychiatric units. People with a diagnosis of BD or SCZ were invited to participate. SI, SP, and SA (suicidality for short) were assessed and associated factors were examined using binary logistical regression. The 1-year prevalence of SI, SP and SA in BD patients were 58.3%, (95% CI: 54.1–62.6%), 38.4% (95% CI: 34.3–42.6%) and 38.6% (95% CI: 34.5–42.8%), respectively, which were higher than the corresponding figures in SCZ patients (SI: 33.2%, 95% CI: 28.6–37.8%; SP: 16.8%, 95% CI: 13.2–20.5%; SA: 19.4%, 95% CI: 15.5–23.3%). Patients with younger age, experience of cyberbullying, a history of SA among family or friends, a higher fatigue and physical pain score, inpatient status, and severe depressive symptoms were more likely to have suicidality. The COVID-19 pandemic was associated with increased risk of suicidality, particularly in BD patients. It is of importance to regularly screen suicidality in BD and SCZ patients during the pandemic even if they are clinically stable.

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Indexed BySCIE
WOS Research AreaPsychiatry
WOS SubjectPsychiatry
WOS IDWOS:000833028400002
Scopus ID2-s2.0-85135148433
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Document TypeJournal article
CollectionUniversity of Macau
Corresponding AuthorAn, Feng Rong; Xiang, Yu Tao
Affiliation1.Department of Psychiatry, Xiamen Xianyue Hospital, Xiamen, China
2.Unit of Psychiatry, Department of Public Health and Medicinal Administration, & Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao
3.Centre for Cognitive and Brain Sciences, University of Macau, Macao
4.Institute of Advanced Studies in Humanities and Social Sciences, University of Macau, Macao
5.Medical College of Soochow University, Suzhou, China
6.Guangji Hospital Affiliated to Soochow University, Suzhou, Jiangsu province, China
7.Nanning Fifth People’s Hospital, Nanning, Guangxi province, China
8.Department of Psychiatry, Lanzhou University Second Hospital, Lanzhou, Gansu province, China
9.Department of Psychiatry, Chaohu Hospital, Anhui Medical University, Hefei, China
10.School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, China
11.School of Public Health, Lanzhou University, Lanzhou, Gansu province, China
12.Department of Psychiatry, University of Saskatchewan, Saskatoon, Canada
13.School of Nursing, Hong Kong Polytechnic University, Hong Kong
14.School of Public Health, Southeast University, Nanjing, China
15.The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital & the Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China
Corresponding Author AffilicationFaculty of Health Sciences;  University of Macau
Recommended Citation
GB/T 7714
Li, Yu Chen,Bai, Wei,Cai, Hong,et al. Suicidality in clinically stable bipolar disorder and schizophrenia patients during the COVID-19 pandemic[J]. Translational Psychiatry,2022,12(1).
APA Li, Yu Chen,Bai, Wei,Cai, Hong,Wu, Yuxuan,Zhang, Ling,Ding, Yan Hong,Yang, Juan Juan,Du, Xiangdong,Zeng, Zhen Tao,Lu, Chang Mou,Feng, Ke Xin,Mi, Wen Fang,Zhang, Lan,Liu, Huan Zhong,Balbuena, Lloyd,Cheung, Teris,Su, Zhaohui,An, Feng Rong,&Xiang, Yu Tao.(2022).Suicidality in clinically stable bipolar disorder and schizophrenia patients during the COVID-19 pandemic.Translational Psychiatry,12(1).
MLA Li, Yu Chen,et al."Suicidality in clinically stable bipolar disorder and schizophrenia patients during the COVID-19 pandemic".Translational Psychiatry 12.1(2022).
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