UM  > Institute of Chinese Medical Sciences
Cellular nanointerface of vertical nanostructure arrays and its applications
Zhang, A.; Feng, J.; Li, X.; Wang, J.; Chen, M.; Chen, H.; He, G.; Xie, X.
Source PublicationNanoscale Advances
AbstractVertically standing nanostructures with various morphologies have been developed with the emergence of the micro-/nanofabrication technology. When cells are cultured on them, various bio–nano interfaces between cells and vertical nanostructures would impact the cellular activities, depending on the shape, density, and height of nanostructures. Many cellular pathway activation processes involving a series of intracellular molecules (proteins, RNA, DNA, enzymes, etc.) would be triggered by the cell morphological changes induced by nanostructures, affecting the cell proliferation, apoptosis, differentiation, immune activation, cell adhesion, cell migration, and other behaviors. In addition, the highly localized cellular nanointerface enhances coupled stimulation on cells. Therefore, understanding the mechanism of the cellular nanointerface can not only provide innovative tools for regulating specific cell functions but also offers new aspects to understand the fundamental cellular activities that could facilitate the precise monitoring and treatment of diseases in the future. This review mainly describes the fabrication technology of vertical nanostructures, analyzing the formation of cellular nanointerfaces and the effects of cellular nanointerfaces on cells' fates and functions. At last, the applications of cellular nanointerfaces based on various nanostructures are summarized.
URLView the original
The Source to ArticlePB_Publication
PUB ID63205
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorXie, X.
Recommended Citation
GB/T 7714
Zhang, A.,Feng, J.,Li, X.,et al. Cellular nanointerface of vertical nanostructure arrays and its applications[J]. Nanoscale Advances,2022:N-N.
APA Zhang, A.,Feng, J.,Li, X.,Wang, J.,Chen, M.,Chen, H.,He, G.,&Xie, X..(2022).Cellular nanointerface of vertical nanostructure arrays and its applications.Nanoscale Advances,N-N.
MLA Zhang, A.,et al."Cellular nanointerface of vertical nanostructure arrays and its applications".Nanoscale Advances (2022):N-N.
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