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Functional properties, structural studies and chemo-enzymatic synthesis of oligosaccharides
Zhao, Chao1,2; Wu, Yijing1; Liu, Xiaoyan1; Liu, Bin1; Cao, Hui3; Yu, Hua3; Sarker, Satyajit D.4; Nahar, Lutfun4; Xiao, Jianbo3

Oligosaccharides offer beneficial effects on immune system and gut health, such as anticancer activity, immunomodulatory activity, and complement activation. Functional oligosaccharides are widely found in plants, algae, bacteria and higher fungi. Milk oligosaccharides, especially human milk oligosaccharides, have considerable health benefits, such as the growth-promotion of the beneficial bacterial flora in the intestines, and developing resistance to bactertial and viral infections. Recent developments in high performance liquid chromatography, mass spectrometry, nuclear magnetic resonance and capillary electrophoresis techniques contribute to the analysis of the oligosaccharide identification and mixture quantification. Synthesis of oligosaccharides is becoming increasingly important to pharmaceutical industries, in which chemo-enzymatic synthesis is considered as an effective method. This article gives a brief summary of structures, accessible sources, physiological and chemical characteristics, and potential health benefits of functional oligosaccharides. (C) 2017 Elsevier Ltd. All rights reserved.

KeywordOligosaccharides Functional Properties Structural Analysis Milk Oligosaccharides Chemo-enzymatic Synthesis
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Indexed BySCIE
WOS Research AreaFood Science & Technology
WOS SubjectFood Science & Technology
WOS IDWOS:000405763100013
The Source to ArticleWOS
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Cited Times [WOS]:49   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China
2.Department of Chemistry, University of California, Davis 95616, USA
3.Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macau
4.Medicinal Chemistry and Natural Products Research Group, School of Pharmacy and Biomolecular Sciences, Faculty of Science, Liverpool John Moores University, James Parsons Building, Byrom Street, Liverpool L3 3AF, UK
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GB/T 7714
Zhao, Chao,Wu, Yijing,Liu, Xiaoyan,et al. Functional properties, structural studies and chemo-enzymatic synthesis of oligosaccharides[J]. TRENDS IN FOOD SCIENCE & TECHNOLOGY,2017,66:135-145.
APA Zhao, Chao,Wu, Yijing,Liu, Xiaoyan,Liu, Bin,Cao, Hui,Yu, Hua,Sarker, Satyajit D.,Nahar, Lutfun,&Xiao, Jianbo.(2017).Functional properties, structural studies and chemo-enzymatic synthesis of oligosaccharides.TRENDS IN FOOD SCIENCE & TECHNOLOGY,66,135-145.
MLA Zhao, Chao,et al."Functional properties, structural studies and chemo-enzymatic synthesis of oligosaccharides".TRENDS IN FOOD SCIENCE & TECHNOLOGY 66(2017):135-145.
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