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Single and multiphoton responsive nanomaterials for the investigation of cancer microenvironment
Li,Yue1; Lee,Chien Wei2; Wang,Yu Chi2; Huang,Chih Chia2; Liu,Tzu Ming1
2018
Source PublicationHandbook of Nanomaterials for Cancer Theranostics
PublisherELSEVIER SCIENCE BV
Pages63-95
Abstract

Diseases like cancer or diabetes mellitus have complicated pathologies which involve the dynamics of molecular milieu and cellular population. To investigate the pathophysiological microenvironment in this context, many functional probes based on photonic nanomaterials have been developed. The critical parameters include oxygen level, pH value, temperature, calcium ion concentration, ATP level, glucose level, reactive oxygen species, hallmark proteins, and the presence of signaling ligands. These parameters can be time-course sensed and read to reveal the dynamic features of critical molecules in pathology. In this chapter, we will introduce various single and multiphoton fluorescence/phosphorescence nanoprobes for the in vivo quantification of critical molecules. Design to overcome biological barriers and degradation in certain disease contexts will be discussed.

KeywordCancer Nanoprobe Optical Imaging Photonic Nanomaterial Physiological Parameter Tumor Microenvironment
DOI10.1016/B978-0-12-813339-2.00003-7
URLView the original
Language英語English
ISBN9780128133392;9780128133408;
WOS IDWOS:000533498900004
WOS SubjectOncology ; Nanoscience & Nanotechnology ; Materials Science, bioMaterials
WOS Research AreaOncology ; Science & Technology - Other Topics ; Materials Science
Scopus ID2-s2.0-85081939249
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Cited Times [WOS]:5   [WOS Record]     [Related Records in WOS]
Document TypeBook chapter
CollectionFaculty of Health Sciences
Affiliation1.University of Macau,Macao SAR,China
2.National Cheng Kung University,Tainan,Taiwan
First Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Li,Yue,Lee,Chien Wei,Wang,Yu Chi,et al. Single and multiphoton responsive nanomaterials for the investigation of cancer microenvironment:ELSEVIER SCIENCE BV,2018:63-95.
APA Li,Yue,Lee,Chien Wei,Wang,Yu Chi,Huang,Chih Chia,&Liu,Tzu Ming.(2018).Single and multiphoton responsive nanomaterials for the investigation of cancer microenvironment.Handbook of Nanomaterials for Cancer Theranostics,63-95.
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