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SRC-3, a steroid receptor coactivator: Implication in cancer
Li, Licen1,2; Deng, Chu Xia1,2; Chen, Qiang1,2
2021-05-01
Source PublicationInternational Journal of Molecular Sciences
ISSN1661-6596
Volume22Issue:9
Abstract

Steroid receptor coactivator-3 (SRC-3), also known as amplified in breast cancer 1 (AIB1), is a member of the SRC family. SRC-3 regulates not only the transcriptional activity of nuclear receptors but also many other transcription factors. Besides the essential role of SRC-3 in physiological functions, it also acts as an oncogene to promote multiple aspects of cancer. This review updates the important progress of SRC-3 in carcinogenesis and summarizes its mode of action, which provides clues for cancer therapy.

KeywordAib1 Cancer Coactivator Src-3
DOI10.3390/ijms22094760
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS IDWOS:000650344800001
Scopus ID2-s2.0-85105540083
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Cited Times [WOS]:2   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorChen, Qiang
Affiliation1.Cancer Centre, Faculty of Health Sciences, University of Macau, Macao
2.Centre for Precision Medicine Research and Training, Faculty of Health Sciences, University of Macau, Macao
First Author AffilicationCancer Centre;  Faculty of Health Sciences
Corresponding Author AffilicationCancer Centre;  Faculty of Health Sciences
Recommended Citation
GB/T 7714
Li, Licen,Deng, Chu Xia,Chen, Qiang. SRC-3, a steroid receptor coactivator: Implication in cancer[J]. International Journal of Molecular Sciences,2021,22(9).
APA Li, Licen,Deng, Chu Xia,&Chen, Qiang.(2021).SRC-3, a steroid receptor coactivator: Implication in cancer.International Journal of Molecular Sciences,22(9).
MLA Li, Licen,et al."SRC-3, a steroid receptor coactivator: Implication in cancer".International Journal of Molecular Sciences 22.9(2021).
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