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Anti-diabetic effects of natural antioxidants from fruits
Sun, Chongde1,2; Liu, Yilong1; Zhan, Liuhuan1; Rayat, Gina R.3; Xiao, Jianbo4; Jiang, Huamin5; Li, Xian1,2; Chen, Kunsong1,2
Source PublicationTrends in Food Science and Technology
AbstractBackground: Diabetes mellitus (DM), a chronic disease characterized by hyperglycemia, is an increasing global health problem which is associated with various chronic diseases such as hypertension, hyperlipidemia and cardiovascular diseases. Despite traditional insulin therapy, nutrients and nutritional factors are also known to play a significant role in the control and treatment of DM. Scope and approach: This comprehensive review focuses on recent advances in knowledge and understanding of the anti-diabetic effects of fruit consumption. Particular attention will be paid to natural antioxidants found in different fruits that may have anti-diabetic effects in human. Key findings and conclusions: Oxidative stress is an important cause and therapeutic target of DM. Plant-based food such as fruits are rich sources of natural antioxidants. Various epidemiological studies, clinical studies, in vivo and in vitro studies showed that fruits with different phytochemical profiles have the ability to lower blood glucose to normal levels. Bioactive compounds identified to have anti-diabetic activities include phenolic compounds, polysaccharides, vitamin C, and most of them have antioxidant activity or can induce antioxidant systems in different experimental models. Therefore, fruits are good resources of anti-diabetic nutrients and a balanced diet rich in different fruits is recommended for diabetic patients and the pre-diabetic population.
KeywordAnti-diabetic effects Antioxidants Diabetes mellitus Fruits Oxidative stress
URLView the original
Scopus ID2-s2.0-85090147682
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Cited Times [WOS]:29   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Zhejiang Provincial Key Laboratory of Horticultural Plant Integrative Biology, Zhejiang University, Hangzhou, 310058, China
2.The State Agriculture Ministry Laboratory of Horticultural Plant Growth, Development and Quality Improvement, Zhejiang University, Hangzhou, 310058, China
3.Department of Surgery, Ray Rajotte Surgical-Medical Research Institute, Alberta Diabetes Institute, University of Alberta, Edmonton, Canada
4.Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macao
5.Hangzhou Lichuan Ecological Agriculture Development Co., Ltd., Hangzhou, China
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GB/T 7714
Sun, Chongde,Liu, Yilong,Zhan, Liuhuan,et al. Anti-diabetic effects of natural antioxidants from fruits[J]. Trends in Food Science and Technology,2021,117:3-14.
APA Sun, Chongde,Liu, Yilong,Zhan, Liuhuan,Rayat, Gina R.,Xiao, Jianbo,Jiang, Huamin,Li, Xian,&Chen, Kunsong.(2021).Anti-diabetic effects of natural antioxidants from fruits.Trends in Food Science and Technology,117,3-14.
MLA Sun, Chongde,et al."Anti-diabetic effects of natural antioxidants from fruits".Trends in Food Science and Technology 117(2021):3-14.
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