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Isoquinoline alkaloids from the rhizoma of Coptis chinensis
Wang W.; Zhang Q.-W.; Ye W.-C.; Wang Y.-T.
Source PublicationChinese Journal of Natural Medicines

Aim: To study isoquinoline alkaloids of the rhizoma of Coptis chinensis. Methods: Column chromatographic techniques were used for the isolation and purification of chemical constituents of the plant. The structures were elucidated by spectroscopic methods. Results: Seven isoquinoline alkaloids, 8-oxyberberine (1), 8-oxocoptisine (2), 8-oxo-epiberberine (3), 6-([1,3] dioxolo [4,5-g] isoquinoline-5-carbonyl)-2,3-dimethoxy-benzoic acid methyl ester (4), corydaldine (5), noroxyhydrastineine (6) and 6,7-methylenedioxy-1(2H)-isoquinolinone (7) were isolated from this plant. Conclusion: Compounds 1 ∼ 7 were isolated from this plant for the first time.

KeywordCoptis Chinensis Isoquinoline Alkaloids
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Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Corresponding AuthorZhang Q.-W.
Affiliation1.Institute of Chinese Medical Sciences, University of Macao, Macao SAR, China
2.Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China
Recommended Citation
GB/T 7714
Wang W.,Zhang Q.-W.,Ye W.-C.,et al. Isoquinoline alkaloids from the rhizoma of Coptis chinensis[J]. Chinese Journal of Natural Medicines,2007,5(5):348-350.
APA Wang W.,Zhang Q.-W.,Ye W.-C.,&Wang Y.-T..(2007).Isoquinoline alkaloids from the rhizoma of Coptis chinensis.Chinese Journal of Natural Medicines,5(5),348-350.
MLA Wang W.,et al."Isoquinoline alkaloids from the rhizoma of Coptis chinensis".Chinese Journal of Natural Medicines 5.5(2007):348-350.
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