UM  > Institute of Chinese Medical Sciences
Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae - A review
Lu, JJ (Lu, Jin-Jian); Dang, YY (Dang, Yuan-Ye); Huang, M (Huang, Min); Xu, WS (Xu, Wen-Shan); Chen, XP (Chen, Xiu-Ping); Wang, YT (Wang, Yi-Tao)
2012-09-28
Source PublicationJOURNAL OF ETHNOPHARMACOLOGY
Volume143Issue:2Pages:406-411
Abstract

Ethnopharmacological relevance: Rhizoma Curcumae is a popular type of traditional Chinese medicine whose essential oils are widely used in the treatment of cancer in China. This review aims to systematically summarize and analyze the anti-cancer properties of terpenoids, the main components of essential oils in Rhizoma Curcumae, and thus enable the development of new anti-cancer drugs. 

Materials and methods: Information on the recent progress of anti-cancer studies on terpenoids isolated from Rhizoma Curcumae, including beta-elemene, delta-elemene, furanodiene, furanodienone, curcumol, and germacrone, was gathered and analyzed. 

Results: Among these terpenoids, beta-elemene is the most widely studied, whereas delta-elemene, furanodiene, furanodienone, curcumol, and germacrone have just recently attracted the attention of researchers. The anti-cancer effects of these terpenoids are related to the retardation of cell cycle arrest, the induction of apoptosis, and the inhibition of metastasis or tissue invasion, among others. 

Conclusions: Most studies have focused on the in vitro data, and in vivo data is urgently needed. Further insight into the anti-cancer activity and the molecular basis of these compounds, combined with efforts in pharmaceutical chemistry and/or pharmaceutics, will potentially enable the development of new anti-cancer agents. (c) 2012 Elsevier Ireland Ltd. All rights reserved.

KeywordCell-cycle Arrest Chromatography-mass-spectrometry Human Lung-carcinoma Breast-cancer Cells Beta-elemene Delta-elemene In-vitro D-galactosamine/lipopolysaccharide Inhibitory-activity Glioblastoma Cells
Indexed BySCI
WOS Research AreaPlant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine
WOS SubjectPlant Sciences ; Chemistry, Medicinal ; Integrative & Complementary Medicine ; Pharmacology & Pharmacy
WOS IDWOS:000309485000003
Fulltext Access
Citation statistics
Cited Times [WOS]:117   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
AffiliationUniversity of Macau
Recommended Citation
GB/T 7714
Lu, JJ ,Dang, YY ,Huang, M ,et al. Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae - A review[J]. JOURNAL OF ETHNOPHARMACOLOGY,2012,143(2):406-411.
APA Lu, JJ ,Dang, YY ,Huang, M ,Xu, WS ,Chen, XP ,&Wang, YT .(2012).Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae - A review.JOURNAL OF ETHNOPHARMACOLOGY,143(2),406-411.
MLA Lu, JJ ,et al."Anti-cancer properties of terpenoids isolated from Rhizoma Curcumae - A review".JOURNAL OF ETHNOPHARMACOLOGY 143.2(2012):406-411.
Files in This Item: Download All
File Name/Size DocType Version Access License
Lu-2012-Anti-cancer-(345KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Lu, JJ (Lu, Jin-Jian)]'s Articles
[Dang, YY (Dang, Yuan-Ye)]'s Articles
[Huang, M (Huang, Min)]'s Articles
Baidu academic
Similar articles in Baidu academic
[Lu, JJ (Lu, Jin-Jian)]'s Articles
[Dang, YY (Dang, Yuan-Ye)]'s Articles
[Huang, M (Huang, Min)]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Lu, JJ (Lu, Jin-Jian)]'s Articles
[Dang, YY (Dang, Yuan-Ye)]'s Articles
[Huang, M (Huang, Min)]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Lu-2012-Anti-cancer-properties-of-terpenoid.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.