UM  > Institute of Chinese Medical Sciences
Affiliated with RCfalse
Adiponectin, an Unlocking Adipocytokine
Sun, YY; Xun, KL; Wang, CG; Zhao, HY; Bi, HC; Chen, XP; Wang, YT

A large number of studies revealed that adiponectin, a protein secreted specifically by adipose tissue, exhibits antiinflammatory, antiatherogenic, and antidiabetic properties. This 247-amino acid protein contains four differentiable domains and exists in five different configurations, which binds three kinds of receptors. The plasma adiponectin concentration is at amazing microgram level and the gender difference is very clear. Obese subjects showed decreased plasma level of adiponectin while exercise seems to restore it. Many researchers demonstrated that it could be a reliable biomarker for multiple diseases. However, there is controversy about its role in inflammation since its plasma concentration decreases in some inflammatory diseases and increases under some other inflammatory conditions. The signal transduction pathway is still not very clear yet. Could adiponectin be a promising drug target ?.

KeywordAdiponecitn Biomarker Drug Target Exercise Gender Difference Inflammation
URLView the original
Indexed BySCIE
WOS Research AreaCardiovascular System & Cardiology ; Pharmacology & Pharmacy
WOS SubjectCardiac & Cardiovascular Systems ; Pharmacology & Pharmacy
WOS IDWOS:000263243400009
Fulltext Access
Citation statistics
Cited Times [WOS]:65   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionInstitute of Chinese Medical Sciences
Affiliation1.Chengdu Med Coll, Sch Pharm, Chengdu, Peoples R China
2.Peoples Hosp Binzhou, Dept Dermatol, Binzhou, Peoples R China
3.Univ Macau, Inst Chinese Med Sci, Macao, Peoples R China
Recommended Citation
GB/T 7714
Sun, YY,Xun, KL,Wang, CG,et al. Adiponectin, an Unlocking Adipocytokine[J]. CARDIOVASCULAR THERAPEUTICS,2009,27(1):59-75.
APA Sun, YY,Xun, KL,Wang, CG,Zhao, HY,Bi, HC,Chen, XP,&Wang, YT.(2009).Adiponectin, an Unlocking Adipocytokine.CARDIOVASCULAR THERAPEUTICS,27(1),59-75.
MLA Sun, YY,et al."Adiponectin, an Unlocking Adipocytokine".CARDIOVASCULAR THERAPEUTICS 27.1(2009):59-75.
Files in This Item: Download All
File Name/Size Publications Version Access License
Sun_et_al-2009-Cardi(741KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Sun, YY]'s Articles
[Xun, KL]'s Articles
[Wang, CG]'s Articles
Baidu academic
Similar articles in Baidu academic
[Sun, YY]'s Articles
[Xun, KL]'s Articles
[Wang, CG]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Sun, YY]'s Articles
[Xun, KL]'s Articles
[Wang, CG]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Sun_et_al-2009-Cardiovascular_Therapeutics.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.