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Discovering Macrophage Functions Using In Vivo Optical Imaging Techniques
Li, Yue; Liu, Tzu-Ming
2018-03-15
Source PublicationFRONTIERS IN IMMUNOLOGY
ISSN1664-3224
Volume9
Abstract

Macrophages are an important component of host defense and inflammation and play a pivotal role in immune regulation, tissue remodeling, and metabolic regulation. Since macrophages are ubiquitous in human bodies and have versatile physiological functions, they are involved in virtually every disease, including cancer, diabetes, multiple sclerosis, and atherosclerosis. Molecular biological and histological methods have provided critical information on macrophage biology. However, many in vivo dynamic behaviors of macrophages are poorly understood and yet to be discovered. A better understanding of macrophage functions and dynamics in pathogenesis will open new opportunities for better diagnosis, prognostic assessment, and therapeutic intervention. In this article, we will review the advances in macrophage tracking and analysis with in vivo optical imaging in the context of different diseases. Moreover, this review will cover the challenges and solutions for optical imaging techniques during macrophage intravital imaging.

KeywordBioluminescence Imaging Function Intravital Microscopy Macrophage Optical Imaging Cell Tracking
DOI10.3389/fimmu.2018.00502
URLView the original
Indexed BySCIE
Language英語English
WOS Research AreaImmunology
WOS SubjectImmunology
WOS IDWOS:000427521700001
PublisherFRONTIERS MEDIA SA
The Source to ArticleWOS
Scopus ID2-s2.0-85044003478
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Cited Times [WOS]:17   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionFaculty of Health Sciences
Corresponding AuthorLiu, Tzu-Ming
AffiliationFaculty of Health Sciences, University of Macau, Macao, China
First Author AffilicationFaculty of Health Sciences
Corresponding Author AffilicationFaculty of Health Sciences
Recommended Citation
GB/T 7714
Li, Yue,Liu, Tzu-Ming. Discovering Macrophage Functions Using In Vivo Optical Imaging Techniques[J]. FRONTIERS IN IMMUNOLOGY,2018,9.
APA Li, Yue,&Liu, Tzu-Ming.(2018).Discovering Macrophage Functions Using In Vivo Optical Imaging Techniques.FRONTIERS IN IMMUNOLOGY,9.
MLA Li, Yue,et al."Discovering Macrophage Functions Using In Vivo Optical Imaging Techniques".FRONTIERS IN IMMUNOLOGY 9(2018).
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