Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity

doi:10.1002/chem.201705450

UM > Institute of Chinese Medical Sciences

Affiliated with RC	false
Status	已發表Published
	Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity
	Ng, Sze-Wing; Chung, Lai-Hon; Yeung, Chi-Fung; Lo, Hoi-Shing; Shek, Hau-Lam; Kang, Tian-Shu; Leung, Chung-Hang; Ma, Dik-Lung; Wong, Chun-Yuen
	2018-02-06
Source Publication	CHEMISTRY-A EUROPEAN JOURNAL
ISSN	0947-6539
Volume	24 Issue:8 Pages:1779-+
Abstract	The two families of Ru-II- chromene and -chromone complexes isolated in this work represent the first examples of metalated chromene and chromone complexes synthesized through transition-metal-mediated cyclization of phenol-tethered ynone. These unprecedented metalated heterocyclic compounds exhibit remarkable features, such as pH-switchable metal-carbon bonding interactions, photo-triggerable release of organic chromone upon visible-light irradiation, and superior antioxidative property to their organic analogue (1,4-benzopyrone). These findings not only offer mechanistic insights into metal-induced activation of functionalized alkynes, but also add a new dimension to rational design of antioxidants and photo-responsive drug delivery systems.
Keyword	alkynes antioxidants chromones photochemistry ruthenium
DOI	10.1002/chem.201705450
URL	View the original
Indexed By	SCIE
Language	英語English
WOS Research Area	Chemistry
WOS Subject	Chemistry, Multidisciplinary
WOS ID	WOS:000424226000004
Publisher	WILEY-V C H VERLAG GMBH
The Source to Article	WOS
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science
Citation statistics	Cited Times [WOS]:16 [WOS Record] [Related Records in WOS]
Document Type	Journal article
Collection	Institute of Chinese Medical Sciences
Recommended Citation GB/T 7714	Ng, Sze-Wing,Chung, Lai-Hon,Yeung, Chi-Fung,et al. Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity[J]. CHEMISTRY-A EUROPEAN JOURNAL,2018,24(8):1779-+.
APA	Ng, Sze-Wing,Chung, Lai-Hon,Yeung, Chi-Fung,Lo, Hoi-Shing,Shek, Hau-Lam,Kang, Tian-Shu,Leung, Chung-Hang,Ma, Dik-Lung,&Wong, Chun-Yuen.(2018).Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity.CHEMISTRY-A EUROPEAN JOURNAL,24(8),1779-+.
MLA	Ng, Sze-Wing,et al."Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity".CHEMISTRY-A EUROPEAN JOURNAL 24.8(2018):1779-+.

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