Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity

doi:10.1002/chem.201705450

UM > Institute of Chinese Medical Sciences

Affiliated with RC	false
Status	已發表Published
	Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity
	Ng, Sze-Wing; Chung, Lai-Hon; Yeung, Chi-Fung; Lo, Hoi-Shing; Shek, Hau-Lam; Kang, Tian-Shu; Leung, Chung-Hang; Ma, Dik-Lung; Wong, Chun-Yuen
	2018-02-06
Source Publication	CHEMISTRY-A EUROPEAN JOURNAL
ISSN	0947-6539
Volume	24 Issue:8 Pages:1779-+
Abstract	The two families of Ru-II- chromene and -chromone complexes isolated in this work represent the first examples of metalated chromene and chromone complexes synthesized through transition-metal-mediated cyclization of phenol-tethered ynone. These unprecedented metalated heterocyclic compounds exhibit remarkable features, such as pH-switchable metal-carbon bonding interactions, photo-triggerable release of organic chromone upon visible-light irradiation, and superior antioxidative property to their organic analogue (1,4-benzopyrone). These findings not only offer mechanistic insights into metal-induced activation of functionalized alkynes, but also add a new dimension to rational design of antioxidants and photo-responsive drug delivery systems.
Keyword	alkynes antioxidants chromones photochemistry ruthenium
DOI	10.1002/chem.201705450
URL	View the original
Indexed By	SCIE
Language	英語English
WOS Research Area	Chemistry
WOS Subject	Chemistry, Multidisciplinary
WOS ID	WOS:000424226000004
Publisher	WILEY-V C H VERLAG GMBH
The Source to Article	WOS
Fulltext Access	View Full-Text via DOI View Full-Text via Web of Science
Citation statistics	Cited Times [WOS]:15 [WOS Record] [Related Records in WOS]
Document Type	Journal article
Collection	Institute of Chinese Medical Sciences
Recommended Citation GB/T 7714	Ng, Sze-Wing,Chung, Lai-Hon,Yeung, Chi-Fung,et al. Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity[J]. CHEMISTRY-A EUROPEAN JOURNAL,2018,24(8):1779-+.
APA	Ng, Sze-Wing,Chung, Lai-Hon,Yeung, Chi-Fung,Lo, Hoi-Shing,Shek, Hau-Lam,Kang, Tian-Shu,Leung, Chung-Hang,Ma, Dik-Lung,&Wong, Chun-Yuen.(2018).Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity.CHEMISTRY-A EUROPEAN JOURNAL,24(8),1779-+.
MLA	Ng, Sze-Wing,et al."Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-triggerable Chromone Delivery Application, and Antioxidative Activity".CHEMISTRY-A EUROPEAN JOURNAL 24.8(2018):1779-+.

Files in This Item:
There are no files associated with this item.

If you have any objections to this item, please fill out the form below and the administrator will contact you as soon as possible.
Content:
Email：	*
Institution:
Verification Code:	Refresh

Any comments and suggestions are welcomed.
Title:	*
Content:
Email：	*
Verification Code:	Refresh