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Nortriterpenoids from the fruiting bodies of the mushroom Ganoderma resinaceum
Chen X.-Q.1; Chen L.-X.1; Zhao J.1; Tang Y.-P.2; Li S.-P.1
Source PublicationMolecules

Ganoderma resinaceum is usually used as ethnomedicine for immune-regulation, hyperglycemia, and liver disease. To date, only a few chemical constituents have been reported from G. resinaceum. In this study, fifteen nortriterpenoids including six new nortriterpenoids (1–6) and nine known analogs (7–15), were separated and purified from the fruiting bodies of G. resinaceum. New compounds were identified as lucidone I (1), lucidone J (2), lucidone K (3), lucidone I (4), ganosineniol B (5), and ganosineniol C (6), based on analysis of extensive spectroscopic data (high resolution mass spectrometry (HRMS), nuclear magnetic resonance (NMR), infrared (IR), and ultraviolet (UV)). The known compounds were assigned as lucidone A (7), lucidone B (8), lucidone H (9), lucidone E (10), lucidone F (11), lucidone D (12), lucidone C (13), ganoderense F (14), and ganosineniol A (15), by comparing their spectroscopic data with those reported in the literature. Compounds 3, 4, and 7–13 were examined for α-glucosidase inhibitory activity and display no significant activity, but the finding may support that the side chain of ganoderma triterpenoids played an important role in α-glucosidase inhibitory activity.

KeywordGanoderma Resinaceum Lucidones I–l Nortriterpenoid Α-glucosidase
URLView the original
Indexed BySCIE
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS IDWOS:000406621300047
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Cited Times [WOS]:9   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionUniversity of Macau
Corresponding AuthorZhao J.; Li S.-P.
Affiliation1.Universidade de Macau
2.Nanjing University of Traditional Chinese Medicine
First Author AffilicationUniversity of Macau
Corresponding Author AffilicationUniversity of Macau
Recommended Citation
GB/T 7714
Chen X.-Q.,Chen L.-X.,Zhao J.,et al. Nortriterpenoids from the fruiting bodies of the mushroom Ganoderma resinaceum[J]. Molecules,2017,22(7).
APA Chen X.-Q.,Chen L.-X.,Zhao J.,Tang Y.-P.,&Li S.-P..(2017).Nortriterpenoids from the fruiting bodies of the mushroom Ganoderma resinaceum.Molecules,22(7).
MLA Chen X.-Q.,et al."Nortriterpenoids from the fruiting bodies of the mushroom Ganoderma resinaceum".Molecules 22.7(2017).
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