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The anti-cancer properties of terpenoids from Rhizoma Curcumae—A review
Lu, J.; Dang, YY; Huang, M; Xu, WS; Chen, X. P.; Wang, Y. T.
2012-07-20
Source PublicationJournal of Ethnopharmacology
ISSN0378-8741
Pages406-411
Abstract

Ethnopharmacologicalrelevance:RhizomaCurcumae is apopulartypeoftraditionalChinesemedicine whoseessentialoilsarewidelyusedinthetreatmentofcancerinChina.Thisreviewaimsto systematicallysummarizeandanalyzetheanti-cancerpropertiesofterpenoids,themaincomponents of essentialoilsin RhizomaCurcumae, andthusenablethedevelopmentofnewanti-cancerdrugs. Materialsandmethods: Informationontherecentprogressofanti-cancerstudiesonterpenoidsisolated from RhizomaCurcumae, including b-elemene, d-elemene,furanodiene,furanodienone,curcumol,and germacrone,wasgatheredandanalyzed. Results: Among theseterpenoids, b-elemeneisthemostwidelystudied,whereas d-elemene,furano- diene,furanodienone,curcumol,andgermacronehavejustrecentlyattractedtheattentionof researchers.Theanti-cancereffectsoftheseterpenoidsarerelatedtotheretardationofcellcycle arrest,theinductionofapoptosis,andtheinhibitionofmetastasisortissueinvasion,amongothers. Conclusions: Most studieshavefocusedontheinvitrodata,andinvivodataisurgentlyneeded.Further insightintotheanti-canceractivityandthemolecularbasisofthesecompounds,combinedwithefforts in pharmaceuticalchemistryand/orpharmaceutics,willpotentiallyenablethedevelopmentofnew anti-canceragents.

KeywordRhizoma Curcumae Terpenoids Anti-cancer B-elemene
Language英語English
The Source to ArticlePB_Publication
Document TypeJournal article
CollectionUniversity of Macau
Corresponding AuthorChen, X. P.; Wang, Y. T.
Recommended Citation
GB/T 7714
Lu, J.,Dang, YY,Huang, M,et al. The anti-cancer properties of terpenoids from Rhizoma Curcumae—A review[J]. Journal of Ethnopharmacology,2012:406-411.
APA Lu, J.,Dang, YY,Huang, M,Xu, WS,Chen, X. P.,&Wang, Y. T..(2012).The anti-cancer properties of terpenoids from Rhizoma Curcumae—A review.Journal of Ethnopharmacology,406-411.
MLA Lu, J.,et al."The anti-cancer properties of terpenoids from Rhizoma Curcumae—A review".Journal of Ethnopharmacology (2012):406-411.
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