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Network analysis of depressive and anxiety symptoms in adolescents during the later stage of the COVID-19 pandemic
Cai, Hong1,2,3; Bai, Wei1,2,3; Liu, Huanzhong4; Chen, Xu5; Qi, Han5; Liu, Rui5; Cheung, Teris6; Su, Zhaohui7; Lin, Jingxia8; Tang, Yi lang9,10; Jackson, Todd11; Zhang, Qinge5; Xiang, Yu Tao1,2,3
2022-03-10
Source PublicationTranslational Psychiatry
ISSN2158-3188
Volume12Issue:1
Other Abstract

Network analysis is an effective approach for examining complex relationships between psychiatric symptoms. This study was designed to examine item-level relationships between depressive and anxiety symptoms using network analysis in an adolescent sample and identified the most central symptoms within the depressive-anxiety symptoms network model. Depressive and anxiety symptoms were assessed using the Patient Health Questionire-9 (PHQ-9) and Generalized Anxiety Disorder Screener (GAD-7), respectively. The structure of depressive and anxiety symptoms was characterized using “Strength” and “Bridge Strength” as centrality indices in the symptom network. Network stability was tested using a case-dropping bootstrap procedure. Finally, a Network Comparison Test (NCT) was conducted to examine whether network characteristics differed on the basis of gender, school grade and residence. Network analysis revealed that nodes PHQ2 (“Sad mood”), GAD6 (“Irritability”), GAD3 (“Worry too much”), and PHQ6 (“Guilty”) were central symptoms in the network model of adolescents. Additionally, bridge symptoms linking anxiety and depressive symptoms in this sample were nodes PHQ6 (“Guilty”), PHQ2 (“Sad mood”), and PHQ9 (“Suicide ideation”). Gender, school grade and residence did not significantly affect the network structure. Central symptoms (e.g., Sad mood, Irritability, Worry too much, and Guilty) and key bridge symptoms (e.g., Guilty, Sad mood, and Suicide ideation) in the depressive and anxiety symptoms network may be useful as potential targets for intervention among adolescents who are at risk for or suffer from depressive and anxiety symptoms.

DOI10.1038/s41398-022-01838-9
URLView the original
Indexed BySCIE ; SSCI
Language英語English
WOS Research AreaPsychiatry
WOS SubjectPsychiatry
WOS IDWOS:000767217900002
Scopus ID2-s2.0-85126254695
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Cited Times [WOS]:2   [WOS Record]     [Related Records in WOS]
Document TypeJournal article
CollectionDEPARTMENT OF PSYCHOLOGY
Faculty of Health Sciences
Corresponding AuthorZhang, Qinge
Affiliation1.Unit of Psychiatry, Department of Public Health and Medicinal Administration, & Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao
2.Centre for Cognitive and Brain Sciences, University of Macau, Macao
3.Institute of Advanced Studies in Humanities and Social Sciences, University of Macau, Macao
4.Department of Psychiatry, Chaohu Hospital of Anhui Medical University, Hefei, Anhui Province, China
5.The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital & the Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China
6.School of Nursing, Hong Kong Polytechnic University, Hong Kong
7.Center on Smart and Connected Health Technologies, Mays Cancer Center, School of Nursing, UT Health San Antonio, San Antonio, United States
8.Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hong Kong
9.Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, United States
10.Atlanta Veterans Affairs Medical Center, Decatur, United States
11.Department of Psychology, Faculty of Social Sciences, University of Macau, Macao
First Author AffilicationFaculty of Health Sciences;  University of Macau
Recommended Citation
GB/T 7714
Cai, Hong,Bai, Wei,Liu, Huanzhong,et al. Network analysis of depressive and anxiety symptoms in adolescents during the later stage of the COVID-19 pandemic[J]. Translational Psychiatry,2022,12(1).
APA Cai, Hong,Bai, Wei,Liu, Huanzhong,Chen, Xu,Qi, Han,Liu, Rui,Cheung, Teris,Su, Zhaohui,Lin, Jingxia,Tang, Yi lang,Jackson, Todd,Zhang, Qinge,&Xiang, Yu Tao.(2022).Network analysis of depressive and anxiety symptoms in adolescents during the later stage of the COVID-19 pandemic.Translational Psychiatry,12(1).
MLA Cai, Hong,et al."Network analysis of depressive and anxiety symptoms in adolescents during the later stage of the COVID-19 pandemic".Translational Psychiatry 12.1(2022).
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