Keywords Cloud

Research Outputs

Co-authors[TOP 5]

Edwin Chong Wing CHEUNG
Title : Professor
Institute: Faculty of Health Sciences
Research Fields: Nuclear Hormone Signaling, Cancer, Sequencing, Estrogen and Androgen
Tel: 8822 4992
Office: (Office) E12-4014 / (Lab) N22-4001
Consultation Hours: Mon, Thu 10:00 – 11:00
Notes: --
Edwin Chong Wing CHEUNG

Research Contents

My lab is interested in understanding the molecular details of nuclear hormone signaling and how these pathways relate to disease conditions, including cancers. Currently, we are investigating how lipophilic hormones such as estrogens and androgens regulate the transcriptional activities of nuclear hormone receptors in the context of a chromatin environment. We employ a combination of powerful biological tools, including modern genetic and cell-based techniques (RNAi, ChIP, and FISH) and next-generation sequencing approaches (ChIP-Seq, RNA-Seq, and ChIA-PET), to define the molecular mechanisms of transcriptional regulation by estrogen and androgen receptors. The findings from our work will have direct impact towards the development of therapeutic targets for the wide range of diseases and disorders in which these and other nuclear receptors play a role.

Research Outputs

Items TC[WOS] TC[Scopus] H-index[WOS] H-index[Scopus]
UM Items TC[WOS] TC[Scopus] H-index[WOS] H-index[Scopus]