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Chaperone-Mediated Autophagy in Neurodegenerative Diseases: Molecular Mechanisms and Pharmacological Opportunities Journal article
Cells, 2022,Volume: 11,Issue: 14
Authors:  Wang, Yi Ting;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/24
Alzheimer’s Disease  Autophagy  Chaperone-mediated Autophagy  Hsc70  Huntington’s Disease  Lamp2a  Neurodegenerative Disease  Parkinson’s Disease  Small Molecule  Α-synuclein  
α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation Journal article
Phytomedicine, 2022,Volume: 101
Authors:  Chen, Jia Yue;  Zhu, Qi;  Cai, Cui Zan;  Luo, Hai Bin;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/31
Alpha-synuclein (Α-syn)  Parkinson's Disease  Phosphodiesterase 4 Inhibitor  Protein Kinase a (Pka)  Ubiquitin-proteasome System (Ups)  
PIWI-interacting RNAs in human diseases: databases and computational models Journal article
Briefings in Bioinformatics, 2022,Volume: 23,Issue: 4,Page: 1-22
Authors:  Zhang, Tianjiao;  Chen, Liang;  Li, Rongzhen;  Ning, Liu;  Huang, Xiaobing;  Wong, Garry
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Recent advances in the biosynthesis, structure–activity relationships, formulations, pharmacology, and clinical trials of fisetin Journal article
eFood, 2022,Volume: 3,Issue: e3
Authors:  Ruting ZHONG;  Mohamed A. Farag;  Meiwan Che;  Chengwei He;  Jianbo Xiao
Adobe PDF | Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/29
Bioactivities  Fisetin  Molecular Mechanism  Pharmacokinetics  Structure–activity Relationship  
Dysregulation of Human Somatic piRNA Expression in Parkinson’s Disease Subtypes and Stages Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 5,Page: 2469
Authors:  Zhang, Tianjiao;  Wong, Garry
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Andrographolide derivative as antagonist of vitamin D receptor to induce lipidation of microtubule associate protein 1 light chain 3 (LC3) Journal article
Bioorganic and Medicinal Chemistry, 2021,Volume: 51
Authors:  Ding, Mo Yu;  Peng, Yuran;  Li, Feng;  Li, Zheng Qing;  Wang, Decai;  Zhou, Guo Chun;  Wang, Ying
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Andrographolide Derivative  Lipidation  Microtubule Associated Protein 1 Light Chain 3  Parkinsonism  Vitamin d Receptor  
Black Phosphorus-Based Nanotherapeutics to Overcome the Blood-Brain Barrier for Parkinson's Disease Conference paper
The 7th Nano Today Conference, Guangzhou, November 15-18, 2021
Authors:  Cheng, Guowang;  Luo, Jingshan;  Liu, Yao;  Chen, Xiaojia;  Wu, Zhenfeng;  Chen, Tongkai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/02
Black Phosphorus Nanosheets  Blood-brain Barrier  Noninvasive Targeted Delivery  Α-synuclein  
Human amyloid beta and α-synuclein co-expression in neurons impair behavior and recapitulate features for Lewy body dementia in Caenorhabditis elegans Journal article
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2021,Volume: 1867,Issue: 10
Authors:  Huang, Xiaobing;  Wang, Changliang;  Chen, Liang;  Zhang, Tianjiao;  Leung, Ka Lai;  Wong, Garry
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/12/08
Amyloid β  Lewy Body Dementia  Lipid Metabolism  Lysosome Function  Α-synuclein  
Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models Journal article
Phytomedicine, 2021,Volume: 87
Authors:  Zhu, Qi;  Zhuang, Xu xu;  Chen, Jia yue;  Yuan, Ning ning;  Chen, Yan;  Cai, Cui zan;  Tan, Jie qiong;  Su, Huan xing;  Lu, Jia hong
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/12/08
Camp/pka Pathway  Lycorine  Parkinson's Disease  Ubiquitin-proteasome System  Α-synuclein  
Natural alkaloid compounds as inhibitors for alpha-synuclein seeded fibril formation and toxicity Journal article
Molecules, 2021,Volume: 26,Issue: 12
Authors:  Ghanem, Simona S.;  Fayed, Hend S.;  Zhu, Qi;  Lu, Jia Hong;  Vaikath, Nishant N.;  Ponraj, Janarthanan;  Mansour, Said;  El-Agnaf, Omar M.A.
Favorite |  | TC[WOS]:6 TC[Scopus]:5 | Submit date:2021/12/08
Parkinson’s Disease  Seeded Fibril Formation  Α-synuclein