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Inhibition and structure-activity relationship of dietary flavones against three Loop 1 human gut microbial β-glucuronidases Journal article
International Journal of Biological Macromolecules, 2022
Authors:  Wang, Panpan;  Wu, Rongrong;  Jia, Yifei;  Tang, Puipui;  Zhang, Qingwen;  Wang, Yafan;  Yan, Ru
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Gut Microbial Metabolism  Β-glucuronidases  Gus Inhibitor  Flavones  Structure-activity Relationship  Allosteric Inhibition  
Application of Diels–Alder adducts derived from Morus plants as gut bacterial -glucuronidases inhibitors来源于桑属植物的DA加合物在制备β-G抑制剂中的应用 Patent
专利类型: 发明专利Invention, 专利号: CN114796194 A, 申请日期: 2022-05-27,
Authors:  燕茹;  王盼盼;  陈智强
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Β-glucuronidases Inhibitors  Gut Microbiota  Diels–alder Adducts  Morus Plants  Applications  
Host UDP-glucuronosyltransferases (UGTs) – gut microbial β-glucuronidases (GUSs) axis in metabolic homeostasis and drug exposure Presentation
报告日期: 2022-06-01
Authors:  Yan, Ru
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Gut Microbial Metabolism  Host Udp-glucuronosyltransferases  Gut Microbial Β-glucuronidases  Host Ugts – Gut Microbial Guss Axis  Metabolic Homeostasis  Drug Exposure  
Discovery of a naturally occurring broad-spectrum inhibitor against gut bacterial β-glucuronidases from: Ginkgo biloba Journal article
Food and Function, 2021,Volume: 12,Issue: 22,Page: 11190-11201
Authors:  Bai, Yue;  Chen, Lu;  Wang, Pan Pan;  Tang, Yu Qiang;  Wu, Da Chang;  Zhang, Cui Li;  Zhou, Qi;  Yan, Ru;  Hou, Jie
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Discovery of a naturally occurring broad-spectrum inhibitor against gut bacterial β-glucuronidases from Ginkgo biloba Journal article
Food & Function, 2021,Volume: 12,Issue: 22,Page: 11190-11201
Authors:  Bai, Yue;  Chen, Lu;  Wang, Panpan;  Tang, Yuqiang;  Wu, Dachang;  Zhang, Cuili;  Zhou, Qi;  Yan, Ru;  Hou, Jie
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/31
Gut Microbiota  Β-glucuronidases  Broad-spectrum Inhibitor  Ginkgo Biloba  Amentoflavone  Chinese Medicines  
靶向抑制肠道菌β-葡萄糖醛酸苷酶在肿瘤预防和治疗中的应用 Applications of BGUSs inhibition in tumor prevention and chemotherapy Journal article
Chinese Journal of Clinical Pharmacology and Therapeutics, 2021,Volume: 26,Issue: 8,Page: 964-974
Authors:  吴蓉蓉;  陈智强;  贾翼菲;  陈宏绮;  王盼盼;  燕茹
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Gut Microbiota  Β-glucuronidases  Cancer Risk  Chemotherapy  Gus Inhibitor  
Human gut bacterial β-glucuronidase inhibition: An emerging approach to manage medication therapy Journal article
Biochemical Pharmacology, 2021,Volume: 190
Authors:  Wang, Panpan;  Jia, Yifei;  Wu, Rongrong;  Chen, Zhiqiang;  Yan, Ru
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Β-glucuronidases  Gut Microbial Metabolism  Drug Toxicity  Gus Inhibitor  Gut Microbiota  
Structure-activity relationship of phenolic compounds against human gut bacterial β-glucuronidases Conference proceedings
Beijing, China
Authors:  Wang, Panpan;  Tang, Puipui;  Wei, Bin;  Zhang, Qingwen;  Yan, Ru
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Β-glucuronidases  Structure-activity Relationship  Flavonoids  Gus Inhibitor  Gut Microbiota  
Gut microbial beta-glucuronidases: From enterohepatic cirucation to medication modulation (肠道菌β-葡萄糖醛酸苷酶:从肠肝循环到药物治疗调控) Presentation
报告日期: 2021-04-01
Authors:  Yan, Ru
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Gut Microbial Metabolism  Β-glucuronidases  Enterohepatic Cirucation  Medication Modulation  
肠道菌群代谢药物研究进展 Advances in Gut Microbial Drug Metabolism Journal article
药学进展 Progress in Pharmaceutical Sciences, 2020,Volume: 44,Issue: 2,Page: 83-99
Authors:  Yifei Jia;  Panpan Wang;  Yijia Chen;  Ru Yan
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Gut Microbiota  Drug Metabolism  Host Drug Disposition  Precision Medicine  Β-glucuronidases