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α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation
Journal article
Phytomedicine, 2022,Volume: 101
Authors:
Chen, Jia Yue
;
Zhu, Qi
;
Cai, Cui Zan
;
Luo, Hai Bin
;
Lu, Jia Hong
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
|
Submit date:2022/05/31
Alpha-synuclein (Α-syn)
Parkinson's Disease
Phosphodiesterase 4 Inhibitor
Protein Kinase a (Pka)
Ubiquitin-proteasome System (Ups)
Andrographolide derivative as antagonist of vitamin D receptor to induce lipidation of microtubule associate protein 1 light chain 3 (LC3)
Journal article
Bioorganic and Medicinal Chemistry, 2021,Volume: 51
Authors:
Ding, Mo Yu
;
Peng, Yuran
;
Li, Feng
;
Li, Zheng Qing
;
Wang, Decai
;
Zhou, Guo Chun
;
Wang, Ying
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
|
Submit date:2021/12/08
Andrographolide Derivative
Lipidation
Microtubule Associated Protein 1 Light Chain 3
Parkinsonism
Vitamin d Receptor
Human amyloid beta and α-synuclein co-expression in neurons impair behavior and recapitulate features for Lewy body dementia in Caenorhabditis elegans
Journal article
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2021,Volume: 1867,Issue: 10
Authors:
Huang, Xiaobing
;
Wang, Changliang
;
Chen, Liang
;
Zhang, Tianjiao
;
Leung, Ka Lai
;
Wong, Garry
Favorite
|
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TC[WOS]:
1
TC[Scopus]:
2
|
Submit date:2021/12/08
Amyloid β
Lewy Body Dementia
Lipid Metabolism
Lysosome Function
Α-synuclein
Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models
Journal article
Phytomedicine, 2021,Volume: 87
Authors:
Zhu, Qi
;
Zhuang, Xu xu
;
Chen, Jia yue
;
Yuan, Ning ning
;
Chen, Yan
;
Cai, Cui zan
;
Tan, Jie qiong
;
Su, Huan xing
;
Lu, Jia hong
Favorite
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TC[WOS]:
3
TC[Scopus]:
4
|
Submit date:2021/12/08
Camp/pka Pathway
Lycorine
Parkinson's Disease
Ubiquitin-proteasome System
Α-synuclein
Natural alkaloid compounds as inhibitors for alpha-synuclein seeded fibril formation and toxicity
Journal article
Molecules, 2021,Volume: 26,Issue: 12
Authors:
Ghanem, Simona S.
;
Fayed, Hend S.
;
Zhu, Qi
;
Lu, Jia Hong
;
Vaikath, Nishant N.
;
Ponraj, Janarthanan
;
Mansour, Said
;
El-Agnaf, Omar M.A.
Favorite
|
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TC[WOS]:
3
TC[Scopus]:
3
|
Submit date:2021/12/08
Parkinson’s Disease
Seeded Fibril Formation
Α-synuclein
Corynoxine Protects Dopaminergic Neurons Through Inducing Autophagy and Diminishing Neuroinflammation in Rotenone-Induced Animal Models of Parkinson’s Disease
Journal article
Frontiers in Pharmacology, 2021,Volume: 12
Authors:
Chen, Leilei
;
Huang, Yujv
;
Yu, Xing
;
Lu, Jiahong
;
Jia, Wenting
;
Song, Juxian
;
Liu, Liangfeng
;
Wang, Youcui
;
Huang, Yingyu
;
Xie, Junxia
;
Li, Min
Favorite
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TC[WOS]:
7
TC[Scopus]:
10
|
Submit date:2021/12/07
Autophagy
Corynoxine
Neuroinflammation
Parkinson’s Disease
Rotenone
Α-synuclein
Dysregulation of MicroRNAs and PIWI-Interacting RNAs in a Caenorhabditis elegans Parkinson’s Disease Model Overexpressing Human α-Synuclein and Influence of tdp-1
Journal article
Frontiers in Neuroscience, 2021,Volume: 15
Authors:
Shen, Linjing
;
Wang, Changliang
;
Chen, Liang
;
Wong, Garry
Favorite
|
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TC[WOS]:
4
TC[Scopus]:
4
|
Submit date:2021/12/07
Caenorhabditis Elegans
Microrna
Neurodegenerative Disease
Piwi-interacting Rna
Synucleinopathies
Targeted graphene oxide for drug delivery as a therapeutic nanoplatform against Parkinson's disease
Journal article
Biomaterials Science, 2021,Volume: 9,Issue: 5,Page: 1705-1715
Authors:
Xiong, Sha
;
Luo, Jingshan
;
Wang, Qun
;
Li, Zhongjun
;
Li, Juntong
;
Liu, Qiao
;
Gao, Liqian
;
Fang, Shuhuan
;
Li, Yunyong
;
Pan, Huafeng
;
Wang, Hong
;
Zhang, Yongbin
;
Wang, Qi
;
Chen, Xiaojia
;
Chen, Tongkai
Favorite
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TC[WOS]:
11
TC[Scopus]:
10
|
Submit date:2021/12/07
Essential role for autophagy protein VMP1 in maintaining neuronal homeostasis and preventing axonal degeneration
Journal article
Cell Death and Disease, 2021,Volume: 12,Issue: 1
Authors:
Wang,Panpan
;
Chen,Xi
;
Wang,Yuanyuan
;
Jia,Congcong
;
Liu,Xinyao
;
Wang,Ying
;
Wu,Haifeng
;
Cai,Huaibin
;
Shen,Han Ming
;
Le,Weidong
;
Wang,Panpan
;
Chen,Xi
;
Wang,Yuanyuan
;
Jia,Congcong
;
Liu,Xinyao
;
Wang,Ying
;
Wu,Haifeng
;
Cai,Huaibin
;
Shen,Han Ming
;
Le,Weidong
Favorite
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TC[WOS]:
4
TC[Scopus]:
4
|
Submit date:2021/03/02
TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans
Journal article
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2020,Volume: 1866,Issue: 10
Authors:
Shen,Linjing
;
Wang,Changliang
;
Chen,Liang
;
Leung,Ka Lai
;
Lo,Esther
;
Lakso,Merja
;
Wong,Garry
Favorite
|
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TC[WOS]:
7
TC[Scopus]:
5
|
Submit date:2021/03/02
C. Elegans
Lewy Body Dementia
Neurodegeneration
Parkinson's Disease
Tdp-1/tdp-43
Tdp-43
Α-synuclein