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Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer’s Disease. Oxidative Medicine and Cellular Longevit Journal article
Oxidative Medicine and Cellular Longevity, 2022,Volume: 2022,Page: 21
Authors:  Qin Li;  Limor Rubin;  Marta Silva;  Shuai Li;  Chao Yang;  Philip Lazarovici;  Zheng WH(鄭文華)
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Discovery of three new monoterpenoid indole alkaloids from the leaves of gardneria multiflora and their vasorelaxant and ache inhibitory activities Journal article
Molecules, 2021,Volume: 26,Issue: 23
Authors:  Zhang, Sheng Yuan;  Li, Zi Wei;  Xu, Jie;  Chen, Qiu Ling;  Song, Min;  Zhang, Qing Wen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/01/14
Ache Inhibitory Activity  Gardneria Multiflora  Monoterpenoid Indole Alkaloid  Vasorelaxant Activity  
An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease Journal article
ACS Chemical Neuroscience, 2020,Volume: 11,Issue: 20,Page: 3346-3357
Authors:  Ju,Yaojun;  Chakravarty,Harapriya;  Tam,Kin Yip
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/04
Alzheimer's Disease  Amyloid Beta  Cholinesterase  Dual Inhibition  
A novel isoquinolinium dual inhibitor of cholinesterases and amyloid beta aggregation mitigates neuropathological changes in a triple-transgenic mouse model of Alzheimer’s disease Journal article
ACS Chemical Neuroscience, 2020,Page: 3346-3357
Authors:  Ju, Y.;  Chakravarty, H.;  Tam, K. Y.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/27
Cholinesterase  Amyloid Beta  Dual Inhibition  Alzheimer’s Disease  
Shexiang Baoxin Pill, a Traditional Chinese Herbal Formula, Rescues the Cognitive Impairments in APP/PS1 Transgenic Mice Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Hu,Wei Hui;  Mak,Shing Hung;  Zheng,Zhong Yu;  Xia,Ying Jie;  Xu,Miranda Li;  Duan,Ran;  Dong,Tina Ting Xia;  Li,Shao Ping;  Zhan,Chang Sen;  Shang,Xiao Hui;  Tsim,Karl Wah Keung
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2021/03/01
Acetylcholinesterase  Alzheimer’s Disease  Chinese Medicine  Cognitive Enhancing Effect  Neuroprotective  Shexiang Baoxin Pill  
Pharmacological Activity, Pharmacokinetics, and Toxicity of Timosaponin AIII, a Natural Product Isolated From Anemarrhena asphodeloides Bunge: A Review Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Lin, Yan;  Zhao, Wai Rong;  Shi, Wen Ting;  Zhang, Jing;  Zhang, Kai Yu;  Ding, Qian;  Chen, Xin Lin;  Tang, Jing Yi;  Zhou, Zhong Yan
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Angiogenesis  Apoptosis  Autophagy  Inflammation  Timosaponin Aiii  
Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives Journal article
Drug Development Research, 2020,Volume: 81,Issue: 2,Page: 242-255
Authors:  Chakravarty,Harapriya;  Ju,Yaojun;  Chen,Wen Hua;  Tam,Kin Y.
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Acetylcholinesterase  Alzheimer's Disease  Amyloid Beta  Butyrylcholinesterase  Dual Target Inhibitor  Isoquinolinium  Pyridinium  
Lycodine-type alkaloids from Lycopodiastrum casuarinoides and their acetylcholinesterase inhibitory activity Journal article
Fitoterapia, 2019,Volume: 139
Authors:  Feng,Zheling;  Chen,Shixin;  Wang,Wei;  Feng,Lu;  Dong,Yanyan;  Zou,Yiping;  Ke,Changqiang;  Tang,Chunping;  Yao,Sheng;  Zhang,Haiyan;  Gan,Lishe;  Ye,Yang;  Lin,Ligen
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Ecd  Lycodine-type Alkaloids  Lycopodiaceae  Lycopodiastrum Casuarinoides  Td-dft  
Pharmacological activities of dihydrotanshinone I, a natural product from Salvia miltiorrhiza Bunge Journal article
Pharmacological Research, 2019,Volume: 145
Authors:  Chen,Xiuping;  Yu,Jie;  Zhong,Bingling;  Lu,Jiahong;  Lu,Jin Jian;  Li,Shaojing;  Lu,Yang
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Danshen  Cancer  Anti-inflammation  Cardiovascular Protection  Human Antigen r  Hypoxia-inducible Factor  
Hippocampal Proteomic Alteration in Triple Transgenic Mouse Model of Alzheimer's Disease and Implication of PINK 1 Regulation in Donepezil Treatment Journal article
Journal of Proteome Research, 2019,Volume: 18,Issue: 4,Page: 1542-1552
Authors:  Zhou, Xinhua;  Xiao, Wei;  Su, Zhiyang;  Cheng, Jiehong;  Zheng, Chengyou;  Zhang, Zaijun;  Wang, Yuqiang;  Wang, Liang;  Xu, Benhong;  Li, Shupen;  Yang, Xifei;  Pui Man Hoi, Maggie
Favorite |  | TC[WOS]:17 TC[Scopus]:18 | Submit date:2022/04/15
Alzheimer's Disease (Ad)  Amyloid Beta (Aβ)  Donepezil  Pink 1  Proteomics