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Small molecule-driven SIRT3-autophagy-mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes Journal article
British Journal of Pharmacology, 2020,Volume: 177,Issue: 20,Page: 4645-4665
Authors:  Zhang,Tian;  Fang,Zhujun;  Linghu,Ke Gang;  Liu,Jingxin;  Gan,Lishe;  Lin,Ligen
Favorite |  | TC[WOS]:21 TC[Scopus]:20 | Submit date:2021/03/01
Adipocytes  Adipose Tissue Inflammation  Autophagy  Cycloartane Triterpenoid  Il-1β, Macrophages  Macrophages  Nlrp3 Inflammasome  
HSQ14 inhibits NLRP3 inflammasome activation by preserving mitochondrial integrity and augmenting SIRT3-mediated autophagy Conference paper
Abstract of 18th Meeting of Consortium for Globalization of Chinese Medicine
Authors:  Zhang, T.;  Fang, Z.;  Wang, Y. T.;  Gan, L.;  Lin, L.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/27
SIRT3  adipocytes  autophagy  chaperon mediated autophagy  AMPK  
Cycloartane triterpenoids from Actaea vaginata with anti-inflammatory effects in LPS-stimulated RAW264.7 macrophages Journal article
PHYTOCHEMISTRY, 2019,Volume: 160,Page: 1-10
Authors:  Zhu-JunFang;  TianZhang;  Shi-XinChen;  Yan-LanWang;  Chang-XinZhou;  Jian-XiaMo;  Yong-JiangWu;  You-KaiXu;  Li-GenLin;  Li-SheGan
Favorite |  | TC[WOS]:25 TC[Scopus]:26 | Submit date:2020/03/20
Inducible No Synthase  Actaea Vaginata (Ranunculaceae)  Cycloartane Trinortriterpenoids  Reduced Density Gradient  Nf-kappa b Pathway