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Targeting glucose metabolism to develop anticancer treatments and therapeutic patents Journal article
Expert Opinion on Therapeutic Patents, 2022,Volume: 32,Issue: 4,Page: 441-453
Authors:  Zhou, Yan;  Guo, Yizhen;  Tam, Kin Yip
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2022/05/17
Cancer Glucose Metabolism  Cancer Treatment Patent  Glycolytic Inhibitor  Hexokinase 2 (Hk2)  Lactate Dehydrogenase a (Ldha)  Pyruvate Dehydrogenase Kinase (Pdk)  Warburg Effect  
A review on the emerging roles of pyruvate kinase M2 in anti-leukemia therapy Journal article
International Journal of Biological Macromolecules, 2021,Volume: 193,Page: 1499-1506
Authors:  Yang, Guan Jun;  Wu, Jia;  Leung, Chung Hang;  Ma, Dik Lung;  Chen, Jiong
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2022/01/14
Leukemia  Modulators  Pyruvate Kinase M2  
Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Liu,Jie;  Yang,Shuo;  Cao,Bihui;  Zhou,Guangyu;  Zhang,Fengjuan;  Wang,Yuan;  Wang,Rixin;  Zhu,Lipeng;  Meng,Ya;  Hu,Cong;  Liang,Hui;  Lin,Xu;  Zhu,Kangshun;  Chen,Guokai;  Luo,Kathy Qian;  Di,Lijun;  Zhao,Qi
Favorite |  | TC[WOS]:15 TC[Scopus]:16 | Submit date:2021/03/04
B7-h3  Bike  Bispecific Antibody  Car t  Chimeric Antigen Receptor  Non-small Cell Lung Cancer  Pd-l1  
Nuclear hkii–p-p53 (Ser15) interaction is a prognostic biomarker for chemoresponsiveness and glycolytic regulation in epithelial ovarian cancer Journal article
Cancers, 2021,Volume: 13,Issue: 14
Authors:  Han, Chae Young;  Patten, David A.;  Kim, Se Ik;  Lim, Jung Jin;  Chan, David W.;  Siu, Michelle K.Y.;  Han, Youngjin;  Carmona, Euridice;  Parks, Robin J.;  Lee, Cheol;  Di, Li Jun;  Lu, Zhen;  Chan, Karen K.L.;  Ku, Ja Lok;  Macdonald, Elizabeth A.;  Vanderhyden, Barbara C.;  Mes-Masson, Anne Marie;  Ngan, Hextan Y.S.;  Cheung, Annie N.Y.;  Song, Yong Sang;  Bast, Robert C.;  Harper, Mary Ellen;  Tsang, Benjamin K.
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/12/08
Cancer Metabolism  Chemoresistance  Epithelial Ovarian Cancer  Hexokinase Ii  P-p53 (Ser15)  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
ACS Combinatorial Science, 2018,Volume: 20,Issue: 11,Page: 660-671
Authors:  Zhang W.;  Hu X.;  Chakravarty H.;  Yang Z.;  Tam K.Y.
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2018/12/18
cancer  high-throughput screening  pyruvate dehydrogenase kinase 1  small molecule inhibitors  Warburg effect  
Identification of Novel Pyruvate Dehydrogenase Kinase 1 (PDK1) Inhibitors by Kinase Activity-Based High-Throughput Screening for Anticancer Therapeutics Journal article
ACS Combinatoral Science, 2018,Page: 660-671
Authors:  Zhang, W.;  Hu, X.;  Chakravarty, H.;  Yang, Z.;  Tam, K. Y.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/28
Cancer  Warburg effect  high-throughput screening  pyruvate dehydrogenase kinase 1  small molecule inhibitors  
Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
JOURNAL OF PROTEOME RESEARCH, 2018,Volume: 17,Issue: 9,Page: 3012-3021
Authors:  Zhang, Wen;  Hu, Xiaohui;  Zhou, Wei;  Tam, Kin Yip
Favorite |  | TC[WOS]:12 TC[Scopus]:10 | Submit date:2018/10/30
Aerobic Glycolysis  Azd7545  Dichloroacetate  Lc-ms/ms  Pyruvate Dehydrogenase Kinases  Cancer Metabolism  
Liquid Chromatography–Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors Journal article
Journal of Proteome Research, 2018,Page: 1-10
Authors:  Zhang, W.;  Hu, X.;  Zhou, W.;  Tam, K. Y.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/28
aerobic glycolysis  AZD7545  cancer metabolism  dichloroacetate  LC−MS/MS  pyruvate dehydrogenase kinases  
High-Intensity Interval Training in Normobaric Hypoxia Improves Cardiorespiratory Fitness in Overweight Chinese Young Women Journal article
Frontiers in Physiology, 2017,Volume: 8,Page: Article 175
Authors:  Kong,Zhaowei;  Shi,Qingde;  Nie,Jinlei;  Tong,Tomas K.;  Song,Lili;  Yi,Longyan;  Hu,Yang
Adobe PDF | Favorite |  | TC[WOS]:18 TC[Scopus]:19 | Submit date:2018/10/30
Normobaric Hypoxia  High-intensity Interval Training  Maximal Oxygen Uptake  Blood Lipids  Leptin  Body Composition  
Short sprints (30 s) attenuate post-prandial blood glucose in young healthy males Journal article
Primary Care Diabetes, 2015,Volume: 9,Issue: 6,Page: 446-450
Authors:  Chan-Dewar,Fang;  Kong,Zhaowei;  Shi,Qingde;  Nie,Jinlei
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2020/11/06
Diabetes  Glycemic Control  Intensity Exercise  Sprint Interval  Wingate Test