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A multi-omics analysis for prediction of neurocognitive disorders risk among the elderly in Macao. Clinical and Translational Medicine
Journal article
Clinical and Translational Medicine, 2022,Volume: 12,Page: e909
Authors:
Yan Han
;
Xingping Quan
;
Yaochen Chuang
;
Qiaoxing Liang
;
Yang Li
;
Zhen Yuan
;
Ying Bian
;
Lai Wei
;
JiWang
;
Yonghua Zhao
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Submit date:2022/07/29
Exosomes
Gut Microbiota
Multi-omics
Neurocognitive Disorders
Artemisinin Attenuates Amyloid-Induced Brain Inflammation and Memory Impairments by Modulating TLR4/NF-κB Signaling
Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 11
Authors:
Zhao, Xia
;
Huang, Xiaosu
;
Yang, Chao
;
Jiang, Yizhou
;
Zhou, Wenshu
;
Zheng, Wenhua
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Submit date:2022/08/02
Alzheimer’s Disease
Artemisinin
Cognitive Disorder
Microglia
Neuroinflammation
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models
Journal article
Redox Biology, 2022,Volume: 51
Authors:
Iyaswamy, Ashok
;
Wang, Xueli
;
Krishnamoorthi, Senthilkumar
;
Kaliamoorthy, Venkatapathy
;
Sreenivasmurthy, Sravan G.
;
Kumar Durairajan, Siva Sundara
;
Song, Ju Xian
;
Tong, Benjamin Chun kit
;
Zhu, Zhou
;
Su, Cheng Fu
;
Liu, Jia
;
Cheung, King Ho
;
Lu, Jia Hong
;
Tan, Jie Qiong
;
Li, Hung Wing
;
Wong, Man Shing
;
Li, Min
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TC[WOS]:
1
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Submit date:2022/05/13
3xtg-ad
5xfad
Alzheimer's Disease
Aβ-aggregate Inhibition
Aβ-targeting
Theranostic
A synergized machine learning plus cross-species wet-lab validation approach identifies neuronal mitophagy inducers inhibiting Alzheimer disease
Journal article
Autophagy, 2022,Volume: 18,Issue: 4,Page: 939-941
Authors:
Ai, Ruixue
;
Zhuang, Xu Xu
;
Anisimov, Alexander
;
Lu, Jia Hong
;
Fang, Evandro F.
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Submit date:2022/05/17
Aging
Alzheimer’s Disease
Autophagy
Machine Learning
Mitophagy
Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles
Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 4,Page: 1688-1706
Authors:
Deng, Zhiqiang
;
Dong, Yu
;
Zhou, Xiaoting
;
Lu, Jia Hong
;
Yue, Zhenyu
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Submit date:2022/05/13
Alzheimer's disease
Autophagy
Autophagy modulators
Genetic modulation
LC3-associated phagocytosis
Microglial autophagy
Neuroinflammation
Neuronal autophagy
Intelligent lesion blood–brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection
Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 4,Page: 1987-1999
Authors:
He, Xueqin
;
Wang, Xiaorong
;
Yang, Lianyi
;
Yang, Zhihang
;
Yu, Wenqi
;
Wang, Yazhen
;
Liu, Rui
;
Chen, Meiwan
;
Gao, Huile
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TC[WOS]:
5
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5
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Submit date:2022/05/13
Alzheimer's disease
Anti-neuroinflammation
Blood‒brain barrier transcytosis
Drug combination
Nano drug delivery system
Neuroprotection
Receptor for advanced glycation end products
ROS-responsive
Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer’s Disease
Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 7
Authors:
Guan, Xinjie
;
Iyaswamy, Ashok
;
Sreenivasmurthy, Sravan Gopalkrishnashetty
;
Su, Chengfu
;
Zhu, Zhou
;
Liu, Jia
;
Kan, Yuxuan
;
Cheung, King Ho
;
Lu, Jiahong
;
Tan, Jieqiong
;
Li, Min
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Submit date:2022/05/04
Aggrephagy
Alzheimer’s Disease
Lipophagy
Lysophagy
Mitophagy
Nucleophagy
Pexophagy
Reticulophagy
Ribophagy
Selective Autophagy
Multi-scale 3D convolution feature-based Broad Learning System for Alzheimer's Disease diagnosis via MRI images
Journal article
Applied Soft Computing, 2022,Volume: 120
Authors:
Han, Ruizhi
;
Liu, Zhulin
;
Chen, C. L.Philip
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TC[WOS]:
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Submit date:2022/05/13
Alzheimer's Disease
Broad Learning System
Convolutional Neural Network
Image Classification
Magnetic Resonance Imaging
Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential
Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1019-1040
Authors:
Zhang, Wei
;
Xu, Chengchao
;
Sun, Jichao
;
Shen, Han Ming
;
Wang, Jigang
;
Yang, Chuanbin
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TC[WOS]:
2
TC[Scopus]:
5
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Submit date:2022/04/06
Alzheimer's Disease (Ad)
Amyloid Beta (Aβ) Peptides
Autophagy
Autophagy Enhancers
Autophagy–lysosomal Pathway
Mapt/tau
Mitophagy
Neurodegenerative Diseases
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease
Journal article
Autophagy, 2022,Volume: 18,Issue: 3,Page: 624-642
Authors:
Tong, Benjamin Chun Kit
;
Wu, Aston Jiaxi
;
Huang, Alexis Shiying
;
Dong, Rui
;
Malampati, Sandeep
;
Iyaswamy, Ashok
;
Krishnamoorthi, Senthilkumar
;
Sreenivasmurthy, Sravan Gopalkrishnashetty
;
Zhu, Zhou
;
Su, Chengfu
;
Liu, Jia
;
Song, Juxian
;
Lu, Jia Hong
;
Tan, Jieqiong
;
Pan, Weidong
;
Li, Min
;
Cheung, King Ho
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TC[WOS]:
7
TC[Scopus]:
8
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Submit date:2022/05/17
Alzheimer Disease
Autophagy-lysosomal Pathway
Calcium Ion
Presenilin-1
Two Pore Segment Channel 2