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A multi-omics analysis for prediction of neurocognitive disorders risk among the elderly in Macao. Clinical and Translational Medicine Journal article
Clinical and Translational Medicine, 2022,Volume: 12,Page: e909
Authors:  Yan Han;  Xingping Quan;  Yaochen Chuang;  Qiaoxing Liang;  Yang Li;  Zhen Yuan;  Ying Bian;  Lai Wei;  JiWang;  Yonghua Zhao
Adobe PDF | Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/07/29
Exosomes  Gut Microbiota  Multi-omics  Neurocognitive Disorders  
Artemisinin Attenuates Amyloid-Induced Brain Inflammation and Memory Impairments by Modulating TLR4/NF-κB Signaling Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 11
Authors:  Zhao, Xia;  Huang, Xiaosu;  Yang, Chao;  Jiang, Yizhou;  Zhou, Wenshu;  Zheng, Wenhua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/02
Alzheimer’s Disease  Artemisinin  Cognitive Disorder  Microglia  Neuroinflammation  
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Redox Biology, 2022,Volume: 51
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.;  Kumar Durairajan, Siva Sundara;  Song, Ju Xian;  Tong, Benjamin Chun kit;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Cheung, King Ho;  Lu, Jia Hong;  Tan, Jie Qiong;  Li, Hung Wing;  Wong, Man Shing;  Li, Min
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2022/05/13
3xtg-ad  5xfad  Alzheimer's Disease  Aβ-aggregate Inhibition  Aβ-targeting  Theranostic  
A synergized machine learning plus cross-species wet-lab validation approach identifies neuronal mitophagy inducers inhibiting Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 4,Page: 939-941
Authors:  Ai, Ruixue;  Zhuang, Xu Xu;  Anisimov, Alexander;  Lu, Jia Hong;  Fang, Evandro F.
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Aging  Alzheimer’s Disease  Autophagy  Machine Learning  Mitophagy  
Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 4,Page: 1688-1706
Authors:  Deng, Zhiqiang;  Dong, Yu;  Zhou, Xiaoting;  Lu, Jia Hong;  Yue, Zhenyu
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Alzheimer's disease  Autophagy  Autophagy modulators  Genetic modulation  LC3-associated phagocytosis  Microglial autophagy  Neuroinflammation  Neuronal autophagy  
Intelligent lesion blood–brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 4,Page: 1987-1999
Authors:  He, Xueqin;  Wang, Xiaorong;  Yang, Lianyi;  Yang, Zhihang;  Yu, Wenqi;  Wang, Yazhen;  Liu, Rui;  Chen, Meiwan;  Gao, Huile
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Alzheimer's disease  Anti-neuroinflammation  Blood‒brain barrier transcytosis  Drug combination  Nano drug delivery system  Neuroprotection  Receptor for advanced glycation end products  ROS-responsive  
Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer’s Disease Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 7
Authors:  Guan, Xinjie;  Iyaswamy, Ashok;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Su, Chengfu;  Zhu, Zhou;  Liu, Jia;  Kan, Yuxuan;  Cheung, King Ho;  Lu, Jiahong;  Tan, Jieqiong;  Li, Min
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Aggrephagy  Alzheimer’s Disease  Lipophagy  Lysophagy  Mitophagy  Nucleophagy  Pexophagy  Reticulophagy  Ribophagy  Selective Autophagy  
Multi-scale 3D convolution feature-based Broad Learning System for Alzheimer's Disease diagnosis via MRI images Journal article
Applied Soft Computing, 2022,Volume: 120
Authors:  Han, Ruizhi;  Liu, Zhulin;  Chen, C. L.Philip
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Alzheimer's Disease  Broad Learning System  Convolutional Neural Network  Image Classification  Magnetic Resonance Imaging  
Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1019-1040
Authors:  Zhang, Wei;  Xu, Chengchao;  Sun, Jichao;  Shen, Han Ming;  Wang, Jigang;  Yang, Chuanbin
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Alzheimer's Disease (Ad)  Amyloid Beta (Aβ) Peptides  Autophagy  Autophagy Enhancers  Autophagy–lysosomal Pathway  Mapt/tau  Mitophagy  Neurodegenerative Diseases  
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 3,Page: 624-642
Authors:  Tong, Benjamin Chun Kit;  Wu, Aston Jiaxi;  Huang, Alexis Shiying;  Dong, Rui;  Malampati, Sandeep;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Zhu, Zhou;  Su, Chengfu;  Liu, Jia;  Song, Juxian;  Lu, Jia Hong;  Tan, Jieqiong;  Pan, Weidong;  Li, Min;  Cheung, King Ho
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2022/05/17
Alzheimer Disease  Autophagy-lysosomal Pathway  Calcium Ion  Presenilin-1  Two Pore Segment Channel 2