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Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Redox Biology, 2022,Volume: 51
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.;  Kumar Durairajan, Siva Sundara;  Song, Ju Xian;  Tong, Benjamin Chun kit;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Cheung, King Ho;  Lu, Jia Hong;  Tan, Jie Qiong;  Li, Hung Wing;  Wong, Man Shing;  Li, Min
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
3xtg-ad  5xfad  Alzheimer's Disease  Aβ-aggregate Inhibition  Aβ-targeting  Theranostic  
A synergized machine learning plus cross-species wet-lab validation approach identifies neuronal mitophagy inducers inhibiting Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 4,Page: 939-941
Authors:  Ai, Ruixue;  Zhuang, Xu Xu;  Anisimov, Alexander;  Lu, Jia Hong;  Fang, Evandro F.
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Aging  Alzheimer’s Disease  Autophagy  Machine Learning  Mitophagy  
Pharmacological modulation of autophagy for Alzheimer's disease therapy: Opportunities and obstacles Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 4,Page: 1688-1706
Authors:  Deng, Zhiqiang;  Dong, Yu;  Zhou, Xiaoting;  Lu, Jia Hong;  Yue, Zhenyu
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Alzheimer's disease  Autophagy  Autophagy modulators  Genetic modulation  LC3-associated phagocytosis  Microglial autophagy  Neuroinflammation  Neuronal autophagy  
Intelligent lesion blood–brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 4,Page: 1987-1999
Authors:  He, Xueqin;  Wang, Xiaorong;  Yang, Lianyi;  Yang, Zhihang;  Yu, Wenqi;  Wang, Yazhen;  Liu, Rui;  Chen, Meiwan;  Gao, Huile
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Alzheimer's disease  Anti-neuroinflammation  Blood‒brain barrier transcytosis  Drug combination  Nano drug delivery system  Neuroprotection  Receptor for advanced glycation end products  ROS-responsive  
Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer’s Disease Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 7
Authors:  Guan, Xinjie;  Iyaswamy, Ashok;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Su, Chengfu;  Zhu, Zhou;  Liu, Jia;  Kan, Yuxuan;  Cheung, King Ho;  Lu, Jiahong;  Tan, Jieqiong;  Li, Min
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Aggrephagy  Alzheimer’s Disease  Lipophagy  Lysophagy  Mitophagy  Nucleophagy  Pexophagy  Reticulophagy  Ribophagy  Selective Autophagy  
Multi-scale 3D convolution feature-based Broad Learning System for Alzheimer's Disease diagnosis via MRI images Journal article
Applied Soft Computing, 2022,Volume: 120
Authors:  Han, Ruizhi;  Liu, Zhulin;  Chen, C. L.Philip
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Alzheimer's Disease  Broad Learning System  Convolutional Neural Network  Image Classification  Magnetic Resonance Imaging  
Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1019-1040
Authors:  Zhang, Wei;  Xu, Chengchao;  Sun, Jichao;  Shen, Han Ming;  Wang, Jigang;  Yang, Chuanbin
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2022/04/06
Alzheimer's Disease (Ad)  Amyloid Beta (Aβ) Peptides  Autophagy  Autophagy Enhancers  Autophagy–lysosomal Pathway  Mapt/tau  Mitophagy  Neurodegenerative Diseases  
Pathological mechanisms and therapeutic strategies for Alzheimer's disease Journal article
Neural Regeneration Research, 2022,Volume: 17,Issue: 3,Page: 543-549
Authors:  Ju, Yaojun;  Tam, Kin
Favorite |  | TC[WOS]:14 TC[Scopus]:9 | Submit date:2022/03/28
Alzheimer's Disease  Drug Development  Multiple Pathologies  Pathological Pathways  
Natural Dietary Compound Xanthohumol Regulates the Gut Microbiota and Its Metabolic Profile in a Mouse Model of Alzheimer’s Disease Journal article
Molecules, 2022,Volume: 27,Issue: 4
Authors:  Liu, Wei;  He, Kaiwu;  Wu, Desheng;  Zhou, Li;  Li, Guowei;  Lin, Zequn;  Yang, Xifei;  Liu, Jianjun;  Hoi, Maggie Pui Man
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16s Rdna Sequencing  Alzheimer’s Disease  Gut Microbiota  Microbial Diversity  Xanthohumol  
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition Journal article
Phytomedicine, 2022,Volume: 96
Authors:  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Senapati, Sanjib;  Malampati, Sandeep;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Guan, Xin Jie;  Tong, Benjamin Chun Kit;  Cheung, King Ho;  Tan, Jie Qiong;  Lu, Jia Hong;  Durairajan, Siva Sundara Kumar;  Song, Ju Xian;  Li, Min
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2022/03/04
3xtg-ad Mice  Alzheimer's Disease  Hdac6  P301s-tau Mice  Phospho-tau  Protopine