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Isolation of Glycoside Compounds from Pulsatilla Chinensis and Their Bioactivities Thesis
Master of Philosophy, Macau: University of Macau, 2022
Authors:  Yuxin ZHAO, Chengwei HE
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Pulsatilla Chinensis  Cimicifuga Dahurica  Triterpenoid  Apoptosis  Anti-inflammation  
A multi-omics analysis for prediction of neurocognitive disorders risk among the elderly in Macao. Clinical and Translational Medicine Journal article
Clinical and Translational Medicine, 2022,Volume: 12,Page: e909
Authors:  Yan Han;  Xingping Quan;  Yaochen Chuang;  Qiaoxing Liang;  Yang Li;  Zhen Yuan;  Ying Bian;  Lai Wei;  JiWang;  Yonghua Zhao
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Exosomes  Gut Microbiota  Multi-omics  Neurocognitive Disorders  
Artemisinin Attenuates Amyloid-Induced Brain Inflammation and Memory Impairments by Modulating TLR4/NF-κB Signaling Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 11
Authors:  Zhao, Xia;  Huang, Xiaosu;  Yang, Chao;  Jiang, Yizhou;  Zhou, Wenshu;  Zheng, Wenhua
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Alzheimer’s Disease  Artemisinin  Cognitive Disorder  Microglia  Neuroinflammation  
Recent advances in the biosynthesis, structure–activity relationships, formulations, pharmacology, and clinical trials of fisetin Journal article
eFood, 2022,Volume: 3,Issue: e3
Authors:  Ruting ZHONG;  Mohamed A. Farag;  Meiwan Che;  Chengwei He;  Jianbo Xiao
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Bioactivities  Fisetin  Molecular Mechanism  Pharmacokinetics  Structure–activity Relationship  
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Redox Biology, 2022,Volume: 51
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.;  Kumar Durairajan, Siva Sundara;  Song, Ju Xian;  Tong, Benjamin Chun kit;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Cheung, King Ho;  Lu, Jia Hong;  Tan, Jie Qiong;  Li, Hung Wing;  Wong, Man Shing;  Li, Min
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3xtg-ad  5xfad  Alzheimer's Disease  Aβ-aggregate Inhibition  Aβ-targeting  Theranostic  
Pathological mechanisms and therapeutic strategies for Alzheimer's disease Journal article
Neural Regeneration Research, 2022,Volume: 17,Issue: 3,Page: 543-549
Authors:  Ju, Yaojun;  Tam, Kin
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Alzheimer's Disease  Drug Development  Multiple Pathologies  Pathological Pathways  
Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1019-1040
Authors:  Zhang, Wei;  Xu, Chengchao;  Sun, Jichao;  Shen, Han Ming;  Wang, Jigang;  Yang, Chuanbin
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Alzheimer's Disease (Ad)  Amyloid Beta (Aβ) Peptides  Autophagy  Autophagy Enhancers  Autophagy–lysosomal Pathway  Mapt/tau  Mitophagy  Neurodegenerative Diseases  
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 3,Page: 624-642
Authors:  Tong, Benjamin Chun Kit;  Wu, Aston Jiaxi;  Huang, Alexis Shiying;  Dong, Rui;  Malampati, Sandeep;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Zhu, Zhou;  Su, Chengfu;  Liu, Jia;  Song, Juxian;  Lu, Jia Hong;  Tan, Jieqiong;  Pan, Weidong;  Li, Min;  Cheung, King Ho
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Alzheimer Disease  Autophagy-lysosomal Pathway  Calcium Ion  Presenilin-1  Two Pore Segment Channel 2  
Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 3
Authors:  Yue, Qian;  Zhou, Xinhua;  Zhang, Zaijun;  Hoi, Maggie Pui Man
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Astrocytes  Blood–brain Barrier  Endothelial Cells  Murine Amyloid-beta  Tight Junctions  Vegfr2 Signaling Pathway  
Putative Factors Interfering Cell Cycle Re-Entry in Alzheimer's Disease: An Omics Study with Differential Expression Meta-Analytics and Co-Expression Profiling Journal article
Journal of Alzheimer's Disease, 2022,Volume: 85,Issue: 3,Page: 1373-1398
Authors:  Yuen, Sze Chung;  Lee, Simon Ming Yuen;  Leung, Siu Wai
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Alzheimer's Disease  Cell Cycle Re-entry  Co-expression Analysis  Meta-analysis  Pagerank Algorithm