UM

Browse/Search Results:  1-10 of 80 Help

Selected(0)Clear Items/Page:    Sort:
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Redox Biology, 2022,Volume: 51
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.;  Kumar Durairajan, Siva Sundara;  Song, Ju Xian;  Tong, Benjamin Chun kit;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Cheung, King Ho;  Lu, Jia Hong;  Tan, Jie Qiong;  Li, Hung Wing;  Wong, Man Shing;  Li, Min
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
3xtg-ad  5xfad  Alzheimer's Disease  Aβ-aggregate Inhibition  Aβ-targeting  Theranostic  
Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1019-1040
Authors:  Zhang, Wei;  Xu, Chengchao;  Sun, Jichao;  Shen, Han Ming;  Wang, Jigang;  Yang, Chuanbin
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2022/04/06
Alzheimer's Disease (Ad)  Amyloid Beta (Aβ) Peptides  Autophagy  Autophagy Enhancers  Autophagy–lysosomal Pathway  Mapt/tau  Mitophagy  Neurodegenerative Diseases  
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 3,Page: 624-642
Authors:  Tong, Benjamin Chun Kit;  Wu, Aston Jiaxi;  Huang, Alexis Shiying;  Dong, Rui;  Malampati, Sandeep;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Zhu, Zhou;  Su, Chengfu;  Liu, Jia;  Song, Juxian;  Lu, Jia Hong;  Tan, Jieqiong;  Pan, Weidong;  Li, Min;  Cheung, King Ho
Favorite |  | TC[WOS]:5 TC[Scopus]:7 | Submit date:2022/05/17
Alzheimer Disease  Autophagy-lysosomal Pathway  Calcium Ion  Presenilin-1  Two Pore Segment Channel 2  
Pathological mechanisms and therapeutic strategies for Alzheimer's disease Journal article
Neural Regeneration Research, 2022,Volume: 17,Issue: 3,Page: 543-549
Authors:  Ju, Yaojun;  Tam, Kin
Favorite |  | TC[WOS]:14 TC[Scopus]:9 | Submit date:2022/03/28
Alzheimer's Disease  Drug Development  Multiple Pathologies  Pathological Pathways  
Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 3
Authors:  Yue, Qian;  Zhou, Xinhua;  Zhang, Zaijun;  Hoi, Maggie Pui Man
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/03/04
Astrocytes  Blood–brain Barrier  Endothelial Cells  Murine Amyloid-beta  Tight Junctions  Vegfr2 Signaling Pathway  
Putative Factors Interfering Cell Cycle Re-Entry in Alzheimer's Disease: An Omics Study with Differential Expression Meta-Analytics and Co-Expression Profiling Journal article
Journal of Alzheimer's Disease, 2022,Volume: 85,Issue: 3,Page: 1373-1398
Authors:  Yuen, Sze Chung;  Lee, Simon Ming Yuen;  Leung, Siu Wai
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2022/05/17
Alzheimer's Disease  Cell Cycle Re-entry  Co-expression Analysis  Meta-analysis  Pagerank Algorithm  
Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow Journal article
Nature Biomedical Engineering, 2022,Volume: 6,Issue: 1,Page: 76-93
Authors:  Xie, Chenglong;  Zhuang, Xu Xu;  Niu, Zhangming;  Ai, Ruixue;  Lautrup, Sofie;  Zheng, Shuangjia;  Jiang, Yinghui;  Han, Ruiyu;  Gupta, Tanima Sen;  Cao, Shuqin;  Lagartos-Donate, Maria Jose;  Cai, Cui Zan;  Xie, Li Ming;  Caponio, Domenica;  Wang, Wen Wen;  Schmauck-Medina, Tomas;  Zhang, Jianying;  Wang, He ling;  Lou, Guofeng;  Xiao, Xianglu;  Zheng, Wenhua;  Palikaras, Konstantinos;  Yang, Guang;  Caldwell, Kim A.;  Caldwell, Guy A.;  Shen, Han Ming;  Nilsen, Hilde;  Lu, Jia Hong;  Fang, Evandro F.
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2022/02/21
Oxyphylla A ameliorates cognitive deficits and alleviates neuropathology via the Akt-GSK3β and Nrf2-Keap1-HO-1 pathways in vitro and in vivo murine models of Alzheimer's disease Journal article
Journal of Advanced Research, 2021,Volume: 34,Page: 1-12
Authors:  Bian, Yaqi;  Chen, Yan;  Wang, Xiufen;  Cui, Guozhen;  Ung, Carolina Oi Lam;  Lu, Jia Hong;  Cong, Weihong;  Tang, Benqin;  Lee, Simon Ming Yuen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
Alzheimer's disease  Amyloid beta proteins  Oxidative stress  oxyphylla A  SAMP8  
Icariin ameliorate Alzheimer's disease by influencing SIRT1 and inhibiting Aβ cascade pathogenesis Journal article
Journal of Chemical Neuroanatomy, 2021,Volume: 117
Authors:  Chuang, Yaochen;  Van, Iatkio;  Zhao, Yonghua;  Xu, Youhua
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
Alzheimer's Disease  Amyloid-β Cascade  Icariin  Sirtuin1  Traditional Chinese Medicine  
Human amyloid beta and α-synuclein co-expression in neurons impair behavior and recapitulate features for Lewy body dementia in Caenorhabditis elegans Journal article
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2021,Volume: 1867,Issue: 10
Authors:  Huang, Xiaobing;  Wang, Changliang;  Chen, Liang;  Zhang, Tianjiao;  Leung, Ka Lai;  Wong, Garry
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/12/08
Amyloid β  Lewy Body Dementia  Lipid Metabolism  Lysosome Function  Α-synuclein