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Myricetin inhibits interferon-γ-induced PD-L1 and IDO1 expression in lung cancer cells Journal article
Biochemical Pharmacology, 2022,Volume: 197
Authors:  Chen, Yu Chi;  He, Xin Ling;  Qi, Lu;  Shi, Wei;  Yuan, Luo Wei;  Huang, Mu Yang;  Xu, Yu Lian;  Chen, Xiuping;  Gu, Lei;  Zhang, Le Le;  Lu, Jin Jian
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/03/28
Indoleamine 2, 3-dioxygenase 1  Interferon-γ  Lung Cancer  Myricetin  Programmed Death Ligand-1  
Inhibition of the CDK9–cyclin T1 protein–protein interaction as a new approach against triple-negative breast cancer Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1390-1405
Authors:  Cheng, Sha Sha;  Qu, Yuan Qing;  Wu, Jia;  Yang, Guan Jun;  Liu, Hao;  Wang, Wanhe;  Huang, Qi;  Chen, Feng;  Li, Guodong;  Wong, Chun Yuen;  Wong, Vincent Kam Wai;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/04/06
Epigenetics  Kinase Inhibitor  Metal Complex  Metastasis  Protein–protein Interaction  Triple-negative Breast Cancer  
ATP11B inhibits breast cancer metastasis in a mouse model by suppressing externalization of nonapoptotic phosphatidylserine Journal article
Journal of Clinical Investigation, 2022,Volume: 132,Issue: 5
Authors:  Xu, Jun;  Su, Sek Man;  Zhang, Xin;  Chan, Un In;  Adhav, Ragini;  Shu, Xiaodong;  Liu, Jianlin;  Li, Jianjie;  Mo, Lihua;  Wang, Yuqing;  An, Tingting;  Lei, Josh Haipeng;  Miao, Kai;  Deng, Chu Xia;  Xu, Xiaoling
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Methylaervine as Potential Lead Compound Against Cervical Carcinoma: Pharmacologic Mechanism Prediction based on Network Pharmacology Journal article
Current Computer-Aided Drug Design, 2022,Volume: 18,Issue: 1,Page: 73-80
Authors:  Dan, Wenjia;  Xu, Yujie;  Gu, Hongling;  Gao, Jixiang;  Dai, Jiangkun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/03/28
ADME study  Antitumor activity  Docking  Methylaervine  Network pharmacology  Synthesis  
The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway Journal article
Phytomedicine, 2022,Volume: 94
Authors:  Liu, Zhuyun;  Wu, Xiaoping;  Dai, Kun;  Li, Renkai;  Zhang, Jinming;  Sheng, Dekuan;  Lee, Simon Ming Yuen;  Leung, George Pak Heng;  Zhou, Guo Chun;  Li, Jingjing
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2022/02/21
Andrographolide Derivative  Apoptosis  Colon Cancer  Reactive Oxygen Species  
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Zhang, Chao;  Li, Qingrui;  Qin, Guozheng;  Zhang, Yi;  Li, Chaoying;  Han, Liwen;  Wang, Rongchun;  Wang, Shudan;  Chen, Haixia;  Liu, Kechun;  He, Chengwei
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date：2021/12/09
Anti-angiogenesis  Anti-metastasis  Hepatocellular Carcinoma Cells  Nf-κb/mmp-9/vegf Pathway  Polyphyllin Vii  
Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Liu,Jie;  Yang,Shuo;  Cao,Bihui;  Zhou,Guangyu;  Zhang,Fengjuan;  Wang,Yuan;  Wang,Rixin;  Zhu,Lipeng;  Meng,Ya;  Hu,Cong;  Liang,Hui;  Lin,Xu;  Zhu,Kangshun;  Chen,Guokai;  Luo,Kathy Qian;  Di,Lijun;  Zhao,Qi
Favorite |  | TC[WOS]:11 TC[Scopus]:13 | Submit date：2021/03/04
B7-h3  Bike  Bispecific Antibody  Car t  Chimeric Antigen Receptor  Non-small Cell Lung Cancer  Pd-l1  
Development of arteannuin B sustained-release microspheres for anti-tumor therapy by integrated experimental and molecular modeling approaches Journal article
Pharmaceutics, 2021,Volume: 13,Issue: 8
Authors:  Wang, Yanqing;  Huang, Weijuan;  Wang, Nannan;  Ouyang, Defang;  Xiao, Lifeng;  Zhang, Sirui;  Ou, Xiaozheng;  He, Tingsha;  Yu, Rongmin;  Song, Liyan
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/12/08
Antitumor Activity  Arteannuin b  Microsphere  Molecular Modeling  Pharmacokinetics  Plga  Sustained Release  
Naturally occurring coumestans from plants, their biological activities and therapeutic effects on human diseases Journal article
Pharmacological Research, 2021,Volume: 169
Authors:  Tu, Yanbei;  Yang, Ying;  Li, Yanfang;  He, Chengwei
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Bone Diseases  Coumestan  Mechanisms  Natural Products  Organ Damages  Pharmacological Activity  
Preparation of novel anthraquinone-based aspirin derivatives with anti-cancer activity Journal article
European Journal of Pharmacology, 2021,Volume: 900
Authors:  Lin, Shan;  Zhang, Yue;  Wang, Zeyu;  Zhang, Shuang;  Li, Yingjie;  Fan, Yuhua;  Li, Dan;  Li, Sen;  Bai, Yuhua
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date：2021/12/08
Anthraquinone  Aspirin  Derivatives  Gastric Cancer  Synthesis