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Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu，Biao;  Wang，Zhi Peng;  Liu，Qingwang;  Yang，Xiaohong;  Li，Xuemin;  Huang，Ding;  Qiu，Yanfei;  Tam，Kin Yip;  Zhang，Shao Lin;  He，Yun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/03/04
Cancer metabolism  Proliferation  Pyruvate dehydrogenase kinase  Structure-activity relationship  
The emerging role of KDM5A in human cancer Journal article
Journal of Hematology and Oncology, 2021,Volume: 14,Issue: 1
Authors:  Yang,Guan Jun;  Zhu,Ming Hui;  Lu,Xin Jiang;  Liu,Yan Jun;  Lu,Jian Fei;  Leung,Chung Hang;  Ma,Dik Lung;  Chen,Jiong
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Cancer  Drug Resistance  Histone Methylation  Jumonji c Domain  Kdm5a  Targeted Therapy  
In situ pepsin-assisted needle assembly of magnetic-graphitic-nanocapsules for enhanced gastric retention and mucus penetration Journal article
Nano Today, 2021,Volume: 36
Authors:  Cai，Xinqi;  Xu，Yiting;  Zhao，Lina;  Xu，Jiamei;  Li，Shengkai;  Wen，Chaoqi;  Xia，Xin;  Dong，Qian;  Hu，Xiaoxiao;  Wang，Xiaofeng;  Chen，Long;  Chen，Zhuo;  Tan，Weihong
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date：2021/03/09
Gastric retention  Harsh gastric environment  Magnetic-graphitic-nanocapsule needle  Mucus penetration  Pepsin-assisted assembly  
Recent developments of human monocarboxylate transporter (hMCT) inhibitors as anticancer agents Journal article
Drug Discovery Today, 2021
Authors:  Wu，Puhua;  Zhou，Yan;  Guo，Yizhen;  Zhang，Shao Lin;  Tam，Kin Yip
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date：2021/03/04
Natural Products in Cancer Therapy: Past, Present and Future Journal article
Natural Products and Bioprospecting, 2021
Authors:  Huang,Min;  Lu,Jin Jian;  Ding,Jian
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date：2021/03/02
Antibody–drug Conjugates  Cancer Therapy  Combination Therapy  Drug Discovery  Natural Products  
Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Signal Transduction and Targeted Therapy, 2020,Volume: 5,Issue: 1
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min;  Li,Zheng Qiu;  Qi,Qi;  Lu,Jin Jian;  Fan,Chun Lin;  Chen,Min Feng;  Qi,Ming;  Li,Xiao Bo;  Hong,Jian;  Zhang,Dong Mei;  Ye,Wen Cai
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Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening Journal article
Advanced Science, 2020,Volume: 7,Issue: 23
Authors:  Shao,Fangyuan;  Lyu,Xueying;  Miao,Kai;  Xie,Lisi;  Wang,Haitao;  Xiao,Hao;  Li,Jie;  Chen,Qiang;  Ding,Renbo;  Chen,Ping;  Xing,Fuqiang;  Zhang,Xu;  Luo,Guang Hui;  Zhu,Wenli;  Cheng,Gregory;  Lon,Ng Wai;  Martin,Scott E.;  Wang,Guanyu;  Chen,Guokai;  Dai,Yunlu;  Deng,Chu Xia
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Broad Drug Resistance  Caspase 3 Activation  Patient-derived Organoid  Proteolysis  Rnai Screening  
Regulation of CD47 expression in cancer cells Journal article
Translational Oncology, 2020,Volume: 13,Issue: 12
Authors:  Huang,Can Yu;  Ye,Zi Han;  Huang,Mu Yang;  Lu,Jin Jian
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Cd47  Cytokine  Microrna  Oncogene  Qpctl  
Multifunctional composite nanoparticles based on hyaluronic acid-paclitaxel conjugates for enhanced cancer therapy Journal article
International Journal of Pharmaceutics, 2020,Volume: 589
Authors:  Luo,Kaipei;  Yin,Shaoping;  Zhang,Ruixia;  Yu,Hua;  Wang,Guangji;  Li,Juan
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Enhanced Anticancer Efficacy  Enzyme-sensitive  Hyaluronic Acid  Polymeric Conjugates  Tumor Targeting  
NIR II-excited and ph-responsive ultrasmall nanoplatform for deep optical tissue and drug delivery penetration and effective cancer chemophototherapy Journal article
Molecular Pharmaceutics, 2020,Volume: 17,Issue: 10,Page: 3720-3729
Authors:  Zhao,Qi;  Zhu,Lipeng;  Gao,Duyang;  Xie,Lisi;  Dai,Yunlu
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date：2021/03/04
Chemophototherapy  Drug Delivery Penetration  Optical Tissue Penetration  Photothermal Imaging  Ultrasmall Cus Nanoparticles