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Recent Progress in the Discovery and Design of Antimicrobial Peptides Using Traditional Machine Learning and Deep Learning Journal article
Antibiotics, 2022,Volume: 11,Issue: 10
Authors:  Yan, Jielu;  Cai, Jianxiu;  Zhang, Bob;  Wang, Yapeng;  Wong, Derek F.;  Siu, Shirley W.I.
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2022/11/07
Antimicrobial Peptide  Classification  Deep Learning  Machine Learning  Medicine  Regression  Therapeutic Peptide  
α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation Journal article
Phytomedicine, 2022,Volume: 101
Authors:  Chen, Jia Yue;  Zhu, Qi;  Cai, Cui Zan;  Luo, Hai Bin;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/31
Alpha-synuclein (Α-syn)  Parkinson's Disease  Phosphodiesterase 4 Inhibitor  Protein Kinase a (Pka)  Ubiquitin-proteasome System (Ups)  
In Vitro & In Vivo studies on Identifying and Designing Temporin-1CEh from the Skin Secretion of Rana chensinensis as the Optimized Antibacterial Prototype Drug Journal article
Pharmaceutics, 2022,Page: 604---
Authors:  Ye, Z.;  Zhou , Z.;  Xi, X.;  Zai , Y.;  Zhou, M.;  Chen , X.;  Ma, C.;  Chen, T.;  Wang , L.;  Kwok, H. F.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/06/14
antimicrobial activity  temporin  branched peptide  Galleria mellonella larva model  
In Vitro & In Vivo Studies on Identifying and Designing Temporin-1CEh from the Skin Secretion of Rana chensinensis as the Optimised Antibacterial Prototype Drug Journal article
Pharmaceutics, 2022,Volume: 14,Issue: 3
Authors:  Ye, Zhuming;  Zhou, Xiaowei;  Xi, Xinping;  Zai, Yu;  Zhou, Mei;  Chen, Xiaoling;  Ma, Chengbang;  Chen, Tianbao;  Wang, Lei;  Kwok, Hang Fai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/03/28
Antimicrobial Activity  Branched Peptide  Galleria Mellonella Larva Model  Temporin  
Qingwei San treats oral ulcer subjected to stomach heat syndrome in db/db mice by targeting TLR4/MyD88/NF-κB pathway Journal article
Chinese Medicine, 2022,Volume: 17,Issue: 1,Page: 1
Authors:  Shi, Lu;  An, Yongcheng;  Cheng, Long;  Li, Yiyang;  Li, Huimin;  Wang, Chen;  Lv, Yinglan;  Duan, Yuhui;  Dai, Hongyu;  He, Changhao;  Zhang, Huilin;  Huang, Yan;  Fu, Wanxin;  Wang, Shengpeng;  Zhao, Baosheng;  Wang, Yitao;  Zhao, Yonghua
Adobe PDF | Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date：2022/05/13
Diabetes Mellitus  Oral Ulcer  Qingwei San  Stomach Heat Syndrome  Tlr4/myd88/nf-κb  
Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow Journal article
Nature Biomedical Engineering, 2022,Volume: 6,Issue: 1,Page: 76-93
Authors:  Xie, Chenglong;  Zhuang, Xu Xu;  Zheng WH(鄭文華);  Shen, Han Ming;  Lu, Jia Hong;  Fang, Evandro F
Adobe PDF | Favorite |  | TC[WOS]:39 TC[Scopus]:44 | Submit date：2022/12/12
BING, a novel antimicrobial peptide isolated from Japanese medaka plasma, targets bacterial envelope stress response by suppressing cpxR expression Journal article
Scientific Reports, 2021,Volume: 11,Issue: 1
Authors:  Dong, Miao;  Kwok, Shu Hin;  Humble, Joseph L.;  Liang, Yimin;  Tang, Sze Wing;  Tang, Kin Hung;  Tse, Man Kit;  Lei, Josh Haipeng;  Ramalingam, Rajkumar;  Koohi-Moghadam, Mohamad;  Au, Doris Wai Ting;  Sun, Hongyan;  Lam, Yun Wah
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date：2021/12/09
Aggregation and its influence on the bioactivities of a novel antimicrobial peptide, temporin-pf, and its analogues Journal article
International Journal of Molecular Sciences, 2021,Volume: 22,Issue: 9
Authors:  Zai, Yu;  Xi, Xinping;  Ye, Zhuming;  Ma, Chengbang;  Zhou, Mei;  Chen, Xiaoling;  Siu, Shirley W.I.;  Chen, Tianbao;  Wang, Lei;  Kwok, Hang Fai
Favorite |  | TC[WOS]:9 TC[Scopus]:10 | Submit date：2021/12/07
Antimicrobial Activity  Md Simulation  Peptide Aggregation  Temporin  
Wasp Venom Biochemical Components and Their Potential in Biological Applications and Nanotechnological Interventions Journal article
Toxins, 2021,Volume: 13,Issue: 3
Authors:  Abd El-Wahed, Aida;  Yosri, Nermeen;  Sakr, Hanem H.;  Du, Ming;  Algethami, Ahmed F.M.;  Zhao, Chao;  Abdelazeem, Ahmed H.;  Tahir, Haroon Elrasheid;  Masry, Saad H.D.;  Abdel-Daim, Mohamed M.;  Musharraf, Syed Ghulam;  El-Garawani, Islam;  Kai, Guoyin;  Al Naggar, Yahya;  Khalifa, Shaden A.M.;  El-Seedi, Hesham R.
Favorite |  | TC[WOS]:20 TC[Scopus]:22 | Submit date：2021/12/07
Allergy  Bioactive Compounds  Biomedical Properties  Nanotechnology Applications  Wasp’s Venom  
Celastrol niosome hydrogel has anti-inflammatory effect on skin keratinocytes and circulation without systemic drug exposure in psoriasis mice Journal article
International Journal of Nanomedicine, 2021,Volume: 16,Page: 6171-6182
Authors:  Qiu, Fen;  Xi, Long;  Chen, Shengshuang;  Zhao, Yonghua;  Wang, Zhenping;  Zheng, Ying
Adobe PDF | Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date：2022/05/13
Celastrol Niosome  Keratinocytes  Pharmacokinetics  Psoriasis  Topical Delivery