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Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Wang,Anqi;  Liu,Jiayu;  Yang,Yuhan;  Chen,Zhejie;  Gao,Caifang;  Wang,Zhanguo;  Fu,Chaomei;  Zou,Liang;  Wang,Shengpeng
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Apoptosis  Breast Cancer  Necrosis  Shikonin  Ubiquitination  
Decabromodiphenyl ether induces male reproductive toxicity by activating mitochondrial apoptotic pathway through glycolipid metabolism dysbiosis Journal article
Chemosphere, 2021,Volume: 285
Authors:  Zhang, Yue;  Li, Xiangyang;  Jing, Li;  Zhou, Guiqing;  Sang, Yujian;  Gao, Leqiang;  Jiang, Shuqin;  Shi, Zhixiong;  Ge, Wei;  Sun, Zhiwei;  Zhou, Xianqing
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Apoptosis  Bde-209  Glycolipid Metabolism  Male Reproductive Toxicity  Scap/srebp-1 Pathways  
The Extracts of Angelica sinensis and Cinnamomum cassia from Oriental Medicinal Foods Regulate Inflammatory and Autophagic Pathways against Neural Injury after Ischemic Stroke Journal article
Oxidative Medicine and Cellular Longevity, 2021,Volume: 2021
Authors:  Luo, Cheng;  Chen, Qi;  Liu, Bowen;  Wang, Shengpeng;  Yu, Hualin;  Guan, Xiaowei;  Zhao, Yonghua;  Wang, Yitao
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Silica nanoparticles inducing the apoptosis via microRNA-450b-3p targeting MTCH2 in mice and spermatocyte cell Journal article
Environmental Pollution, 2021,Volume: 277
Authors:  Zhou, Guiqing;  Liu, Jianhui;  Li, Xiangyang;  Sang, Yujian;  Zhang, Yue;  Gao, Leqiang;  Wang, Ji;  Yu, Yang;  Ge, Wei;  Sun, Zhiwei;  Zhou, Xianqing
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Apoptosis Signaling Pathway  Male Reproductive Toxicity  Mirna-450b-3p  Mitochondrial Carrier Homolog 2 (Mtch2)  Silica Nanoparticles (Sinps)  
Fluorescence resonance energy transfer-based sensor zebrafish for detecting toxic agents with single-cell sensitivity Journal article
Journal of Hazardous Materials, 2021,Volume: 408
Authors:  Jia，Hao;  Luo，Kathy Qian
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Cadmium  DNA-damaging agents  FRET imaging  In vivo apoptosis detection  ZnO nanoparticles  
The dietary supplement Rhodiola crenulata extract alleviates dextran sulfate sodium-induced colitis in mice through anti-inflammation, mediating gut barrier integrity and reshaping the gut microbiome Journal article
Food and Function, 2021,Volume: 12,Issue: 7,Page: 3142-3158
Authors:  Wang, Yi;  Tao, Hongxun;  Huang, Huimin;  Xiao, Yaqin;  Wu, Xiaoxiao;  Li, Mingxing;  Shen, Jing;  Xiao, Zhangang;  Zhao, Yueshui;  Du, Fukan;  Ji, Huijiao;  Chen, Yu;  Cho, Chi Hin;  Wang, Yitao;  Wang, Shengpeng;  Wu, Xu
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A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis Journal article
Free Radical Biology and Medicine, 2021,Volume: 166,Page: 104-115
Authors:  Zhong, Bingling;  Yu, Jie;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Lu, Jin Jian;  Chen, Xiuping
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Glioblastoma  Jnk1/2  Noptosis  Nqo1  Tanshindiol b  
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity Journal article
European Journal of Medicinal Chemistry, 2021,Volume: 214
Authors:  Xu，Biao;  Wang，Zhi Peng;  Liu，Qingwang;  Yang，Xiaohong;  Li，Xuemin;  Huang，Ding;  Qiu，Yanfei;  Tam，Kin Yip;  Zhang，Shao Lin;  He，Yun
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Cancer metabolism  Proliferation  Pyruvate dehydrogenase kinase  Structure-activity relationship  
Insulin-like 3 affects zebrafish spermatogenic cells directly and via Sertoli cells Journal article
Communications Biology, 2021,Volume: 4,Issue: 1
Authors:  Crespo, Diego;  Assis, Luiz H.C.;  Zhang, Yu Ting;  Safian, Diego;  Furmanek, Tomasz;  Skaftnesmo, Kai Ove;  Norberg, Birgitta;  Ge, Wei;  Choi, Yung Ching;  den Broeder, Marjo J.;  Legler, Juliette;  Bogerd, Jan;  Schulz, Rüdiger W.
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Modeling Uremic Vasculopathy With Induced Pluripotent Stem Cell-Derived Endothelial Cells as a Drug Screening System Journal article
Frontiers in Cell and Developmental Biology, 2021,Volume: 8
Authors:  Jang,Hye Ryoun;  Cho,Hyung Joon;  Zhou,Yang;  Shao,Ning Yi;  Lee,Kyungho;  Le,Hoai Huong Thi;  Jeon,Junseok;  Lee,Jung Eun;  Huh,Wooseong;  Ong,Sang Ging;  Lee,Won Hee;  Kim,Yoon Goo
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Chronic Kidney Disease  Endothelial Cells  Induced Pluripotent Stem Cells  Uremic Toxin  Uremic Vasculopathy