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Canthin-6-one (CO) from Picrasma quassioides (D.Don) Benn. ameliorates lipopolysaccharide (LPS)-induced astrocyte activation and associated brain endothelial disruption Journal article
Phytomedicine, 2022,Volume: 101
Authors:  Yue, Qian;  Xu, Yunshao;  Lin, Ligen;  Hoi, Maggie Pui Man
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/31
Astrocyte  Blood-brain Barrier (Bbb)  Brain Endothelial Cell  Canthin-6-one (Co)  Endothelial Integrity  Neuroinflammation  
A Neuropeptide Y/F-like Polypeptide Derived from the Transcriptome of Turbinaria peltata Suppresses LPS-Induced Astrocytic Inflammation Journal article
Journal of Natural Products, 2022,Volume: 85,Issue: 6,Page: 1569-1580
Authors:  Chen, Qian;  Liang, Zirong;  Yue, Qian;  Wang, Xiufen;  Siu, Shirley Weng In;  Pui-Man Hoi, Maggie;  Lee, Simon Ming Yuen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/02
Current Progress on Neuroprotection Induced by Artemisia, Ginseng, Astragalus, and Ginkgo Traditional Chinese Medicines for the Therapy of Alzheimer’s Disease. Oxidative Medicine and Cellular Longevit Journal article
Oxidative Medicine and Cellular Longevity, 2022,Volume: 2022,Page: 21
Authors:  Qin Li;  Limor Rubin;  Marta Silva;  Shuai Li;  Chao Yang;  Philip Lazarovici;  Zheng WH(鄭文華)
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Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Redox Biology, 2022,Volume: 51
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.;  Kumar Durairajan, Siva Sundara;  Song, Ju Xian;  Tong, Benjamin Chun kit;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Cheung, King Ho;  Lu, Jia Hong;  Tan, Jie Qiong;  Li, Hung Wing;  Wong, Man Shing;  Li, Min
Favorite |  | TC[WOS]:7 TC[Scopus]:10 | Submit date:2022/05/13
3xtg-ad  5xfad  Alzheimer's Disease  Aβ-aggregate Inhibition  Aβ-targeting  Theranostic  
The secretome of microglia induced by IL-4 of IFN-γ differently regulate proliferation, differentiation and survival of adult neural stem/progenitor cell by targeting the PI3K-Akt pathway Journal article
Cytotechnology, 2022
Authors:  Jiang, Xue;  Yi, Saini;  Liu, Qin;  Zhang, Jinqiang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
Interferon-gamma, Interleukin-4, Neural Stem/progenitor Cell  Microglia  Neurogenesis  Pi3k/akt Pathway  
Murine Beta-Amyloid (1–42) Oligomers Disrupt Endothelial Barrier Integrity and VEGFR Signaling via Activating Astrocytes to Release Deleterious Soluble Factors Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 3
Authors:  Yue, Qian;  Zhou, Xinhua;  Zhang, Zaijun;  Hoi, Maggie Pui Man
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/03/04
Astrocytes  Blood–brain Barrier  Endothelial Cells  Murine Amyloid-beta  Tight Junctions  Vegfr2 Signaling Pathway  
Artemisinin Attenuates Amyloid-Induced Brain Inflammation and Memory Impairments by Modulating TLR4/NF-κB Signaling Journal article
International Journal of Molecular Sciences, 2022,Volume: 2022,Issue: 23,Page: 6354
Authors:  Xia Zhao;  Xiaosu Huang;  Chao Yang;  Yizhou Jiang;  Wenshu Zhou;  Zheng WH(鄭文華)
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Alzheimer’s Disease  Artemisinin  Neuroinflammation  Microglia  Cognitive Disorder  
Crocin protects mouse astrocyte C8-D1A cytotoxicity induced by LPS via regulation of NF-ĸB signaling pathway Conference paper
Medicinal and Food Plant Research & Natural Products and Biodiversity Resources
Authors:  Liang, Z.;  Qian, E.;  Hoi, P. M.
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crocin  astrocyte  neurodegenerative disease  
Tetramethylpyrazine nitrone (TBN), derivative from traditional Chinese medicine Chuan Xiong exerted a protective effect on neurovascular unit against mural amyloid-beta1-42 oligomers Conference paper
Medicinal and Food Plant Research & Natural Products and Biodiversity Resources
Authors:  Qian, E.;  Hoi, P. M.
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TCM  neurovascular unit  amyloid beta  
Engineered exosomes: Desirable target-tracking characteristics for cerebrovascular and neurodegenerative disease therapies Journal article
Theranostics, 2021,Volume: 11,Issue: 18,Page: 8926-8944
Authors:  Xu, Meng;  Feng, Tao;  Liu, Bowen;  Qiu, Fen;  Xu, Youhua;  Zhao, Yonghua;  Zheng, Ying
Adobe PDF | Favorite |  | TC[WOS]:16 TC[Scopus]:18 | Submit date:2022/05/13
Administration Routes  Brain Targeting  Cerebrovascular Disease  Engineered Exosomes  Neurological Disorders  Tracking