UM

Browse/Search Results:  1-6 of 6 Help

Selected(0)Clear Items/Page:    Sort:
Inhibiting β-Amyloid-Associated Alzheimer’s Pathogenesis In Vitro and In Vivo by a Multifunctional Dimeric Bis(12)-hupyridone Derived from Its Natural Analogue Journal article
Journal of Molecular Neuroscience, 2015,Volume: 55,Issue: 4,Page: 1014
Authors:  Shengquan Hu;  Rui Wang;  Wei Cui;  Zaijun Zhang;  Shinghung Mak;  Daping Xu;  Chunglit Choi;  Karl Wahkeung Tsim;  Paul R. Carlier;  Mingyuen Lee;  Yifan Han
Favorite |  | TC[WOS]:15 TC[Scopus]:15 | Submit date:2018/10/30
Alzheimer’s Disease  Aβ Fibrils  Bis(12)-hupyridone  Cell Viability  Memory Impairment  Thioflavin t  
Bis(12)-hupyridone, a promising multi-functional anti-Alzheimer’s dimer derived from Chinese medicine Book chapter
出自: When Things Go Wrong - Diseases and Disorders of the Human Brain:InTech, 2012
Authors:  Wei Cui;  Tony Chung-Lit Choi;  Shinghung Mak;  Hua Yu;  Shengquan Hu;  Wenming Li;  Zhong Zuo
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2019/01/25
Intestinal Transport of Bis(12)-hupyridone in Caco-2 Cells andits Improved Permeability by the Surfactant Brij-35 Journal article
Biopharmaceutics & Drug Disposition, 2011,Volume: 32,Issue: 3,Page: 140–150
Authors:  Hua Yu;  Yue Qing Hu;  Fanny C. F. Ip;  Zhong Zuo;  Yi Fan Han;  Nancy Y. Ip
Favorite |  | TC[WOS]:21 TC[Scopus]:22 | Submit date:2019/01/24
Bis(12)-hupyridone  Absorption  P-glycoprotein  Multidrug Resistance-associated Protein  Nonionic Surfactant  
Bis(12)-hupyridone, a novel multifunctional dimer, promotes neuronal differentiation more potently than its monomeric natural analog huperzine A possibly through alpha7 nAChR Journal article
BRAIN RESEARCH, 2011,Volume: 1401,Issue: 15,Page: 10-17
Authors:  Cui, Wei;  Cui, Guo-Zhen;  Li, Wenming;  Zhang, Zaijun;  Hu, Shengquan;  Mak, Shinghung;  Zhang, Huan;  Carlier, Paul R.;  Choi, Chung-lit;  Wong, Yi-Tao;  Lee, Simon Ming-Yuen;  Han, Yifan
Favorite |  | TC[WOS]:22 TC[Scopus]:23 | Submit date:2018/11/01
Bis(12)-hupyridone  Huperzine a  Neural Stem Cell  Neurodegenerative Disorder  Differentiation  Alpha 7nachr  
Development and validation of an HPLC-DAD method for bis(12)-hupyridone and its application to a pharmacokinetic study Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2009,Volume: 49,Issue: 2,Page: 410
Authors:  Yu H.;  Li W.M.;  Cheung M.C.;  Zuo Z.;  Carlier P.R.;  Gu Z.M.;  Chan K.;  Huang M.;  Wang Y.T.;  Han Y.F.
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2018/10/31
Alzheimer's Disease  Bis(12)-hupyridone  Hplc-dad  Pharmacokinetics  
The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine Journal article
Journal of Pharmaceutical and Biomedical Analysis, 2008,Volume: 46,Issue: 1,Page: 75
Authors:  Yu H.;  Li W.-M.;  Kan K.K.W.;  Ho J.M.K.;  Carlier P.R.;  Pang Y.-P.;  Gu Z.-M.;  Zhong Z.;  Chan K.;  Wang Y.-T.;  Han Y.-F.
Favorite |  | TC[WOS]:34 TC[Scopus]:43 | Submit date:2018/10/30
Ache Inhibition  Bis(12)-hupyridone  Bis(7)-tacrine  Dimer  Ionization Constant  Lipophilicity  Solubility