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NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:6 TC[Scopus]:5 | Submit date:2020/09/16
Framing Ethical Concerns and Attitudes towards Human Gene Patents in the Chinese Press Journal article
Asian Bioethics Review, 2020,Volume: 12,Issue: 3,Page: 307-323
Authors:  Li Du;  Sijie Lin;  Kalina Kamenova
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2020/12/04
Chinese Newspapers  Content Analysis  Human Gene Patents  Patentability  
Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells Journal article
Acta Pharmaceutica Sinica B, 2020,Volume: 10,Issue: 4,Page: 615-627
Authors:  Zhang,Baoyuan;  Lyu,Junfang;  Yang,Eun Ju;  Liu,Yifan;  Wu,Changjie;  Pardeshi,Lakhansing;  Tan,Kaeling;  Chen,Qiang;  Xu,Xiaoling;  Deng,Chu Xia;  Shim,Joong Sup
Favorite |  | TC[WOS]:9 TC[Scopus]:11 | Submit date:2020/09/16
Brca1  Breast Cancer  Dna Damage  Hdac  Histone Deacetylase  Reactive Oxygen Species  Synthetic Lethality  
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:12 TC[Scopus]:12 | Submit date:2020/09/16
Atm-ampk-drp1  Brca1  Inflammasomes  Mitochondrial Dynamics  Mitophagy  
Organism dual RNA-seq reveals the importance of BarA/UvrY in Vibrio parahaemolyticus virulence Journal article
FASEB Journal, 2020,Volume: 34,Issue: 6,Page: 7561-7577
Authors:  Zhang W.;  Xie R.;  Zhang X.D.;  Lee L.T.O.;  Zhang H.;  Yang M.;  Peng B.;  Zheng J.
Adobe PDF | Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2021/03/03
Bara  C. Elegans  Organism Dual Rna-seq  Uvry  V. Parahaemolyticus  Virulence Factor  
Classification of VUS and unclassified variants in BRCA1 BRCT repeats by molecular dynamics simulation Journal article
Computational and Structural Biotechnology Journal, 2020,Volume: 18,Page: 723-736
Authors:  Sinha,Siddharth;  Wang,San Ming
Favorite |  | TC[WOS]:7 TC[Scopus]:9 | Submit date:2021/03/02
BRCA1  BRCT  Molecular dynamics simulation  PCA  Unclassified variants  VUS  
Prevalence of BRCA1 / BRCA2 pathogenic variation in Chinese Han population Journal article
Journal of Medical Genetics, 2020
Authors:  Dong,Hui;  Chandratre,Khyati;  Qin,Yue;  Zhang,Jing;  Tian,Xiaoqing;  Rong,Ce;  Wang,Ning;  Guo,Maoni;  Zhao,Guoping;  Wang,San Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:3 | Submit date:2021/03/02
cancer: breast  genetics  molecular genetics  oncology  prevention  
Germline variation in BRCA1/2 is highly ethnic-specific: Evidence from over 30,000 Chinese hereditary breast and ovarian cancer patients Journal article
International Journal of Cancer, 2019,Volume: 145,Issue: 4,Page: 962-973
Authors:  Bhaskaran,Shanmuga Priya;  Chandratre,Khyati;  Gupta,Hemant;  Zhang,Li;  Wang,Xiaoyu;  Cui,Jian;  Kim,Yeong C.;  Sinha,Siddharth;  Jiang,Luhan;  Lu,Boya;  Wu,Xiaobing;  Qin,Zixin;  Huang,Teng;  Wang,San Ming
Favorite |  | TC[WOS]:18 TC[Scopus]:19 | Submit date:2021/03/02
BRCA1  BRCA2  breast cancer  Chinese  ethnic-specific  mutation  population  
Common genetic variants contribute to incomplete penetrance: evidence from cancer-free BRCA1 mutation carriers Journal article
European Journal of Cancer, 2019,Volume: 107,Page: 68-78
Authors:  Downs,Bradley;  Sherman,Simon;  Cui,Jian;  Kim,Yeong C.;  Snyder,Carrie;  Christensen,Maria;  Luo,Jiangtao;  Lynch,Henry;  Wang,San Ming
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/02
BRCA1  Breast cancer  Cancer resistance  Exome  Variation  
BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1-MCM2 signaling during pregnancy Journal article
Human molecular genetics, 2018
Authors:  Xiaoling Xu;  Eric Chen;  Lihua Mo;  Lei Zhang;  Fangyuan Shao;  Kai Miao;  Jianlin Liu;  Sek Man Su;  Monica Valecha;  Un In Chan;  Hongping Zheng;  Mark Chen;  Weiping Chen;  Qiang Chen;  Haiqing Fu;  Mirit I. Aladjem;  Yanzhen He;  Chu-Xia Deng
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2018/12/17