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Epigenetics of the Immune Component of Inflammation Journal article
Frontiers in Immunology, 2022
Authors:  Liu, Yan-Jun;  Wang, Haitao;  Zhong, Hai-Jing;  Chong, Cheong-Meng;  Yang, Guan-Jun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/12
FGFR2–BRD4 Axis Regulates Transcriptional Networks of Histone 3 Modification and Synergy Between Its Inhibitors and PD-1/PD-L1 in a TNBC Mouse Model Journal article
Frontiers in Immunology, 2022,Volume: 13
Authors:  Lei, Josh Haipeng;  Zhang, Lei;  Wang, Zhenyi;  Peltier, Raoul;  Xie, Yusheng;  Chen, Ganchao;  Lin, Shiqi;  Miao, Kai;  Deng, Chu Xia;  Sun, Hongyan
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/31
BRD4  epigenetic  FGFR2  immunotherapy  posttranslational modifications  TNBC  
An optimized BRD4 inhibitor effectively eliminates NF-κB-driven triple-negative breast cancer cells Journal article
Bioorganic Chemistry, 2021,Volume: 114
Authors:  Yang, Guan Jun;  Song, Ying Qi;  Wang, Wanhe;  Han, Quan Bin;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/12/08
Acetylated Rela  Brd4  Nf-κb  Protein-protein Interaction  Tnbc  
A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2021/03/01
Brd4  BromoDomain Domain  Cell Metastasis And Invasion  Histone Acetylation  Melanoma  Protein–protein Interaction  Virtual Screening  
Iridium (III)-based irreversible protein-protein interaction inhibitor of BRD4 as a potent anticancer agent Patent
专利类型: 发明专利Invention, 专利号: US9840526B1, 申请日期: 2017-07-27,
Authors:  Chung-Hang LEUNG;  Hai-Jing ZHONG;  Dik-Lung MA;  Hui-Min WANG
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/31
Brd4 Inhibitor  
An iridium(III)-based irreversible protein-protein interaction inhibitor of BRD4 as a potent anticancer agent Journal article
Chemical Science, 2015,Volume: 6,Issue: 10,Page: 5400
Authors:  Zhong H.-J.;  Lu L.;  Leung K.-H.;  Wong C.C.L.;  Peng C.;  Yan S.-C.;  Ma D.-L.;  Cai Z.;  David Wang H.-M.;  Leung C.-H.
Favorite |  | TC[WOS]:110 TC[Scopus]:111 | Submit date:2018/10/30
Iridium(III)-based irreversible protein-protein interaction inhibitor of BRD4 as a potent anticancer agent Patent
专利类型: 发明专利, 专利号: US9840526B1, 申请日期: 2017-07-27, 公开日期: 2017-12-12
Authors:  Chung Hang Leung;  Hai Jing Zhong;  Dik Lung Ma;  Hui Min Wang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2020/05/07