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Dihydrotanshinone i Attenuates Plaque Vulnerability in Apolipoprotein E-Deficient Mice: Role of Receptor-Interacting Protein 3 Journal article
Antioxidants and Redox Signaling, 2021,Volume: 34,Issue: 5,Page: 351-363
Authors:  Zhao,Wenwen;  Li,Chunxia;  Zhang,Hao;  Zhou,Qihui;  Chen,Xuehong;  Han,Yantao;  Chen,Xiuping
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ApoE-/-mice  RIP3  TLR4 dimerization  vulnerable  
Regulation of the NLRP3 inflammasome with natural products against chemical-induced liver injury Journal article
Pharmacological Research, 2021,Volume: 164
Authors:  Zou,Jian;  Wang,Sheng Peng;  Wang,Yi Tao;  Wan,Jian Bo
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Acute liver failure  Chemical-induced liver injury  Inflammation  Natural products  NLRP3 inflammasome  
Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells Journal article
Stem Cell Reports, 2020,Volume: 15,Issue: 6,Page: 1362-1376
Authors:  Ren,Zhili;  Zhong,Hui;  Song,Chengcheng;  Deng,Chunhao;  Hsieh,Hsun Ting;  Liu,Weiwei;  Chen,Guokai
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Akt  Caspase  Cell Survival  Gsk3  Human Embryonic Stem Cells  Insulin  Mitochondrial Respiration  
Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening Journal article
Advanced Science, 2020,Volume: 7,Issue: 23
Authors:  Shao,Fangyuan;  Lyu,Xueying;  Miao,Kai;  Xie,Lisi;  Wang,Haitao;  Xiao,Hao;  Li,Jie;  Chen,Qiang;  Ding,Renbo;  Chen,Ping;  Xing,Fuqiang;  Zhang,Xu;  Luo,Guang Hui;  Zhu,Wenli;  Cheng,Gregory;  Lon,Ng Wai;  Martin,Scott E.;  Wang,Guanyu;  Chen,Guokai;  Dai,Yunlu;  Deng,Chu Xia
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Broad Drug Resistance  Caspase 3 Activation  Patient-derived Organoid  Proteolysis  Rnai Screening  
Inactivation of endothelial ADAM17 reduces retinal ischemia-reperfusion induced neuronal and vascular damage Journal article
International Journal of Molecular Sciences, 2020,Volume: 21,Issue: 15,Page: 1-18
Authors:  Gutsaeva,Diana R.;  Shalaby,Lamiaa;  Powell,Folami L.;  Thounaojam,Menaka C.;  Abouhish,Hossameldin;  Wetzstein,Sara A.;  Jadeja,Ravirajsinh N.;  Kwok,Hang Fai;  Martin,Pamela M.;  Bartoli,Manuela
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ADAM17  Neuronal and vascular degeneration  Retinal ischemia-reperfusion  Vascular permeability  
Pristimerin-induced uveal melanoma cell death via inhibiting PI3K/Akt/FoxO3a signalling pathway Journal article
Journal of Cellular and Molecular Medicine, 2020,Volume: 24,Issue: 11,Page: 6208-6219
Authors:  Yan,Fengxia;  Liao,Rifang;  Silva,Marta;  Li,Shuai;  Jiang,Yizhou;  Peng,Tangming;  Lazarovici,Philip;  Zheng,Wenhua
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cell death  FoxO3a  nuclear accumulation  Pristimerin  uveal melanoma  
Engineered Sensor Zebrafish for Fast Detection and Real-Time Tracking of Apoptosis at Single-Cell Resolution in Live Animals Journal article
ACS Sensors, 2020,Volume: 5,Issue: 3,Page: 823-830
Authors:  Jia,Hao;  Song,Yanlong;  Huang,Bin;  Ge,Wei;  Luo,Kathy Qian
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apoptosis  caspase-3  FRET  in vivo imaging  real-time  skin development  zebrafish  
Dietary compound glycyrrhetinic acid suppresses tumor angiogenesis and growth by modulating antiangiogenic and proapoptotic pathways in vitro and in vivo Journal article
Journal of Nutritional Biochemistry, 2020,Volume: 77
Authors:  Li,Jingjing;  Tang,Fan;  Li,Renkai;  Chen,Zhejie;  Lee,Simon Ming Yuen;  Fu,Chaomei;  Zhang,Jinming;  Leung,George Pak Heng
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Antiangiogenesis  Apoptosis  Dietary compound  Glycyrrhetinic acid  Ovarian cancer  
Hyaluronic acid-coated pH sensitive poly (β-amino ester) nanoparticles for co-delivery of embelin and TRAIL plasmid for triple negative breast cancer treatment Journal article
International Journal of Pharmaceutics, 2020,Volume: 573
Authors:  Xu,Yingqi;  Liu,Dingxin;  Hu,Jie;  Ding,Peirong;  Chen,Meiwan
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Co-delivery  Embelin  Hyaluronic acid  pH-sensitive  Plasmid  
Artemisinin improved neuronal functions in Alzheimer's disease animal model 3xtg mice and neuronal cells via stimulating the ERK/CREB signaling pathway Journal article
Aging and Disease, 2020,Volume: 11,Issue: 4,Page: 801-819
Authors:  Zhao,Xia;  Li,Shuai;  Gaur,Uma;  Zheng,Wenhua
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3×Tg mice  Alzheimer's disease  Amyloid beta  Artemisinin  Cognitive behavior  SH-SY5Ycells