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Thyroid hormone enhances stem cell maintenance and promotes lineage-specific differentiation in human embryonic stem cells Journal article
Stem Cell Research and Therapy, 2022,Volume: 13,Issue: 1
Authors:  Deng, Chunhao;  Zhang, Zhaoying;  Xu, Faxiang;  Xu, Jiaqi;  Ren, Zhili;  Godoy-Parejo, Carlos;  Xiao, Xia;  Liu, Weiwei;  Zhou, Zhou;  Chen, Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/13
Cell culture  hPSCs  Pluripotency  Thyroid Hormone  Triiodothyronine (T3)  Trophoblast  
Acetyltanshinone IIA reduces the synthesis of cell cycle-related proteins by degrading p70S6K and subsequently inhibits drug-resistant lung cancer cell growth Journal article
Pharmacological Research, 2022,Volume: 179
Authors:  Huang, Bin;  Hao, Meng;  Li, Chuwen;  Luo, Kathy Qian
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Acetyltanshinone IIA  Afatinib (PubChem CID: 10184653)  Aurora kinase A  Drug-resistant lung cancer  EGFR  Erlotinib (PubChem CID: 176870)  LY294002 (PubChem CID: 3973)  MLN8237 (PubChem CID: 24771867)  Osimertinib (PubChem CID: 71496458)  P70S6K  PF-4708671 (PubChem CID: 51371303)  Rapamycin (PubChem CID: 5284616)  Tanshinone IIA (PubChem CID: 164676)  
PD-1 N58-Glycosylation-Dependent Binding of Monoclonal Antibody Cemiplimab for Immune Checkpoint Therapy Journal article
Frontiers in Immunology, 2022,Volume: 13
Authors:  Lu, Dan;  Xu, Zepeng;  Zhang, Ding;  Jiang, Min;  Liu, Kefang;  He, Juanhua;  Ma, Dongli;  Ma, Xiaopeng;  Tan, Shuguang;  Gao, George F.;  Chai, Yan
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/04/06
Antibody  Cemiplimab  Immune Checkpoint Therapy (Ict)  N58 Glycosylation  Pd-1  
ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy Journal article
Acta Biomaterialia, 2022,Volume: 140,Page: 492-505
Authors:  Yang, Suleixin;  Wong, Ka Hong;  Hua, Peng;  He, Chengwei;  Yu, Hua;  Shao, Dan;  Shi, Zhi;  Chen, Meiwan
Favorite |  | TC[WOS]:0 TC[Scopus]:2 | Submit date：2022/03/28
Ferroptosis  Fluorinated Polyethyleneimine Vector  Gpx4  Mthfd2  
Cell-derived artificial nanovesicle as a drug delivery system for malignant melanoma treatment Journal article
Biomedicine and Pharmacotherapy, 2022,Volume: 147
Authors:  Lin, Ying Yi;  Chen, Chung Yi;  Ma, Dik Lung;  Leung, Chung Hang;  Chang, Chu Yu;  Wang, Hui Min David
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Curcumin  Immune  Melanoma  Metastasis  Nanovesicle  
Orchestrated Yolk–Shell Nanohybrids Regulate Macrophage Polarization and Dendritic Cell Maturation for Oncotherapy with Augmented Antitumor Immunity Journal article
Advanced Materials, 2022,Volume: 34,Issue: 9
Authors:  Zhao, Xiaoyi;  Guo, Kangli;  Zhang, Kai;  Duan, Shun;  Chen, Meiwan;  Zhao, Nana;  Xu, Fu Jian
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Antitumor Immunity  Chemodynamic Therapy  Immunomodulatory Effect  Tumor Microenvironment  Yolk–shell Structure  
c-MYC-mediated TRIB3/P62+ aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2 Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1240-1253
Authors:  Su, Min Xia;  Xu, Yu Lian;  Jiang, Xiao Ming;  Huang, Mu Yang;  Zhang, Le Le;  Yuan, Luo Wei;  Xu, Xiao Huang;  Zhu, Qi;  Gao, Jian Li;  Lu, Jia Hong;  Chen, Xiuping;  Huang, Ming Qing;  Wang, Yitao;  Lu, Jin Jian
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/04/06
Aggresomes  C-myc  Everolimus  Ginsenoside Rh2  Lung Cancer  P62  Paraptosis  Trib3  
Pathological mechanisms and therapeutic strategies for Alzheimer's disease Journal article
Neural Regeneration Research, 2022,Volume: 17,Issue: 3,Page: 543-549
Authors:  Ju, Yaojun;  Tam, Kin
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Alzheimer's Disease  Drug Development  Multiple Pathologies  Pathological Pathways  
Engineering Radiosensitizer-Based Metal-Phenolic Networks Potentiate STING Pathway Activation for Advanced Radiotherapy Journal article
Advanced Materials, 2022,Volume: 34,Issue: 10
Authors:  Yan, Jie;  Wang, Guohao;  Xie, Lisi;  Tian, Hao;  Li, Jie;  Li, Bei;  Sang, Wei;  Li, Wenxi;  Zhang, Zhan;  Dai, Yunlu
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Lanthanide-doped Radiosensitizers  Manganese  Metal–phenolic Networks  Radiosensitization Effects  Stimulator Of Interferon Genes Pathways  
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 3,Page: 624-642
Authors:  Tong, Benjamin Chun Kit;  Wu, Aston Jiaxi;  Huang, Alexis Shiying;  Dong, Rui;  Malampati, Sandeep;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Zhu, Zhou;  Su, Chengfu;  Liu, Jia;  Song, Juxian;  Lu, Jia Hong;  Tan, Jieqiong;  Pan, Weidong;  Li, Min;  Cheung, King Ho
Favorite |  | TC[WOS]:4 TC[Scopus]:7 | Submit date：2022/05/17
Alzheimer Disease  Autophagy-lysosomal Pathway  Calcium Ion  Presenilin-1  Two Pore Segment Channel 2