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Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repression Journal article
Oncogene, 2021,Volume: 40,Issue: 5,Page: 937-950
Authors:  Shi,Changxiang;  Yang,Eun Ju;  Liu,Yifan;  Mou,Pui Kei;  Ren,Guowen;  Shim,Joong Sup
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation Journal article
Theranostics, 2021,Volume: 11,Issue: 4,Page: 1672-1689
Authors:  Li,Licen;  Bao,Jiaolin;  Wang,Haitao;  Lei,Josh Haipeng;  Peng,Cheng;  Zeng,Jianming;  Hao,Wenhui;  Zhang,Xu;  Xu,Xiaoling;  Yu,Chundong;  Deng,Chu Xia;  Chen,Qiang
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/02
Aib1  Ecm  Hedgehog  Mafb  Pdac  
Combined effects of berberine and evodiamine on colorectal cancer cells and cardiomyocytes in vitro Journal article
European Journal of Pharmacology, 2020,Volume: 875
Authors:  Guan, Xiaoyong;  Zheng, Xiaoting;  Vong, Chi Teng;  Zhao, Jinyao;  Xiao, Jianbo;  Wang, Yitao;  Zhong, Zhangfeng
Favorite |  | TC[WOS]:13 TC[Scopus]:11 | Submit date:2021/09/13
Berberine  Cardiomyocyte  Colorectal Cancer  Evodiamine  Synergism  
Dietary compound glycyrrhetinic acid suppresses tumor angiogenesis and growth by modulating antiangiogenic and proapoptotic pathways in vitro and in vivo Journal article
Journal of Nutritional Biochemistry, 2020,Volume: 77
Authors:  Li,Jingjing;  Tang,Fan;  Li,Renkai;  Chen,Zhejie;  Lee,Simon Ming Yuen;  Fu,Chaomei;  Zhang,Jinming;  Leung,George Pak Heng
Favorite |  | TC[WOS]:6 TC[Scopus]:7 | Submit date:2021/03/01
Antiangiogenesis  Apoptosis  Dietary Compound  Glycyrrhetinic Acid  Ovarian Cancer  
Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Liu,Hui;  Liao,Wanqin;  Fan,Lixia;  Zheng,Zhaoguang;  Liu,Dahai;  Zhang,Qing Wen;  Yang,Anping;  Liu,Fang
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/02
Apoptosis  Liver Cancer  Migration  Ophiorrhiza Pumila  Proliferation  
Apoptosis effect of Aegiceras corniculatum on human colorectal cancer via activation of FoxO signaling pathway Journal article
Food and Chemical Toxicology, 2019,Volume: 134
Authors:  Luo, Hua;  Hao, Erwei;  Tan, Dechao;  Wei, Wei;  Xie, Jinling;  Feng, Xiaohui;  Du, Zhengcai;  Huang, Chunying;  Bai, Gang;  Hou, Yuanyuan;  Cheng, Chuanjing;  Yi, Xiangxi;  Wang, Yitao;  Hou, Xiaotao;  Deng, Jiagang
Favorite |  | TC[WOS]:6 TC[Scopus]:5 | Submit date:2021/09/13
Aegiceras Corniculatum  Apoptosis  Cell Cycle  Colorectal Cancer  Forkhead Box  
Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells Journal article
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019,Volume: 71,Issue: 3,Page: 306-315
Authors:  Angela Verma;  Yau-Min Lam;  Yun-Chung Leung;  Xiaohui Hu;  Xin Chen;  Edwin Cheung;  Kin Yip Tam
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2020/05/21
Bacillus Caldovelox Arginase  Breast Cancer  Dichloroacetate  Drug Combination  Pegyated Human Arginase  
Astragalus Polysaccharide RAP Selectively Attenuates Paclitaxel-Induced Cytotoxicity Toward RAW 264.7 Cells by Reversing Cell Cycle Arrest and Apoptosis Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 9
Authors:  Bao, WR;  Li, ZP;  Zhang, QW;  Li, LF;  Liu, HB;  Ma, DL;  Leung, CH;  Lu, AP;  Bian, Z;  Han, QB
Favorite |  | TC[WOS]:9 TC[Scopus]:9 | Submit date:2020/03/24
Cell Cycle  Astragalus Polysaccharide  Cytotoxicity  Protective Effect  Apoptosis  
CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer Journal article
SCIENTIFIC REPORTS, 2019,Volume: 9
Authors:  Houliang Deng;  Xiaowen Guan;  Longcai Gong;  Jianming Zeng;  Hongjie Zhang;  Mike Y. Chen;  Gang Li
Favorite |  | TC[WOS]:13 TC[Scopus]:15 | Submit date:2020/06/22
Structure-Based Discovery of a Selective KDM5A Inhibitor that Exhibits Anti-Cancer Activity via Inducing Cell Cycle Arrest and Senescence in Breast Cancer Cell Lines Journal article
CANCERS, 2019,Volume: 11,Issue: 1
Authors:  Yang, GJ;  Ko, CN;  Zhong, HJ;  Leung, CH;  Ma, DL
Favorite |  | TC[WOS]:17 TC[Scopus]:16 | Submit date:2020/03/24
Cell Cycle Arrest  Kdm5a  Jumonji Domain  Histone Demethylation  Protein-protein Interaction  Virtual Screening  Breast Cancer  Cell Senescence